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The complex and dynamic real-world clinical environment demands reliable deep learning (DL) systems. Out-of-distribution (OOD) detection plays a critical role in enhancing the reliability and generalizability of DL models when encountering…

Computer Vision and Pattern Recognition · Computer Science 2026-04-16 Jiangbei Yue , Darren Treanor , Venkataraman Subramanian , Sharib Ali

To detect distribution shifts and improve model safety, many out-of-distribution (OOD) detection methods rely on the predictive uncertainty or features of supervised models trained on in-distribution data. In this paper, we critically…

Machine Learning · Computer Science 2025-07-03 Yucen Lily Li , Daohan Lu , Polina Kirichenko , Shikai Qiu , Tim G. J. Rudner , C. Bayan Bruss , Andrew Gordon Wilson

Recent advances in deep learning have led to breakthroughs in the development of automated skin disease classification. As we observe an increasing interest in these models in the dermatology space, it is crucial to address aspects such as…

Computer Vision and Pattern Recognition · Computer Science 2021-06-03 Hannah Kim , Girmaw Abebe Tadesse , Celia Cintas , Skyler Speakman , Kush Varshney

We study the problem of Out-of-Distribution (OOD) detection, that is, detecting whether a learning algorithm's output can be trusted at inference time. While a number of tests for OOD detection have been proposed in prior work, a formal…

Machine Learning · Statistics 2023-09-19 Akshayaa Magesh , Venugopal V. Veeravalli , Anirban Roy , Susmit Jha

Out-of-distribution (OOD) detection is concerned with identifying data points that do not belong to the same distribution as the model's training data. For the safe deployment of predictive models in a real-world environment, it is critical…

Sound · Computer Science 2023-02-28 Zaharah Bukhsh , Aaqib Saeed

Pre-trained vision foundation models have transformed many computer vision tasks. Despite their strong ability to learn discriminative and generalizable features crucial for out-of-distribution (OOD) detection, their impact on this task…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Shizhen Zhao , Jiahui Liu , Xin Wen , Haoru Tan , Xiaojuan Qi

The discrepancy between in-distribution (ID) and out-of-distribution (OOD) samples can lead to \textit{distributional vulnerability} in deep neural networks, which can subsequently lead to high-confidence predictions for OOD samples. This…

Machine Learning · Computer Science 2023-10-03 Zhilin Zhao , Longbing Cao , Kun-Yu Lin

Out-of-distribution (OOD) detection is critical for ensuring the reliability of deep learning systems, particularly in safety-critical applications. Likelihood-based deep generative models have historically faced criticism for their…

Machine Learning · Computer Science 2025-07-11 Yifan Ding , Arturas Aleksandraus , Amirhossein Ahmadian , Jonas Unger , Fredrik Lindsten , Gabriel Eilertsen

Multimodal fusion, leveraging data like vision and language, is rapidly gaining traction. This enriched data representation improves performance across various tasks. Existing methods for out-of-distribution (OOD) detection, a critical area…

Computer Vision and Pattern Recognition · Computer Science 2024-08-29 Jinglun Li , Xinyu Zhou , Kaixun Jiang , Lingyi Hong , Pinxue Guo , Zhaoyu Chen , Weifeng Ge , Wenqiang Zhang

The open-world test dataset is often mixed with out-of-distribution (OOD) samples, where the deployed models will struggle to make accurate predictions. Traditional detection methods need to trade off OOD detection and in-distribution (ID)…

Machine Learning · Computer Science 2024-04-25 Xu Shen , Yili Wang , Kaixiong Zhou , Shirui Pan , Xin Wang

In image classification, a lot of development has happened in detecting out-of-distribution (OoD) data. However, most OoD detection methods are evaluated on a standard set of datasets, arbitrarily different from training data. There is no…

Computer Vision and Pattern Recognition · Computer Science 2022-09-27 Jishnu Mukhoti , Tsung-Yu Lin , Bor-Chun Chen , Ashish Shah , Philip H. S. Torr , Puneet K. Dokania , Ser-Nam Lim

Out-of-distribution (OOD) detection is an indispensable aspect of secure AI when deploying machine learning models in real-world applications. Previous paradigms either explore better scoring functions or utilize the knowledge of outliers…

Machine Learning · Computer Science 2023-06-07 Jianing Zhu , Hengzhuang Li , Jiangchao Yao , Tongliang Liu , Jianliang Xu , Bo Han

Recent object detectors have achieved impressive accuracy in identifying objects seen during training. However, real-world deployment often introduces novel and unexpected objects, referred to as out-of-distribution (OOD) objects, posing…

Machine Learning · Computer Science 2025-11-20 Quang-Huy Nguyen , Jin Peng Zhou , Zhenzhen Liu , Khanh-Huyen Bui , Kilian Q. Weinberger , Wei-Lun Chao , Dung D. Le

Recent research has shown that pre-trained vision-language models are effective at identifying out-of-distribution (OOD) samples by using negative labels as guidance. However, employing consistent negative labels across different OOD…

Computer Vision and Pattern Recognition · Computer Science 2024-10-29 Yabin Zhang , Lei Zhang

Recent advancements have explored text-to-image diffusion models for synthesizing out-of-distribution (OOD) samples, substantially enhancing the performance of OOD detection. However, existing approaches typically rely on perturbing…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Xin Gao , Jiyao Liu , Guanghao Li , Yueming Lyu , Jianxiong Gao , Weichen Yu , Ningsheng Xu , Liang Wang , Caifeng Shan , Ziwei Liu , Chenyang Si

Most existing deep learning models are trained based on the closed-world assumption, where the test data is assumed to be drawn i.i.d. from the same distribution as the training data, known as in-distribution (ID). However, when models are…

Machine Learning · Computer Science 2022-11-09 Yixin Liu , Kaize Ding , Huan Liu , Shirui Pan

Out-of-distribution (OOD) detection is important for machine learning models deployed in the wild. Recent methods use auxiliary outlier data to regularize the model for improved OOD detection. However, these approaches make a strong…

Machine Learning · Computer Science 2022-06-30 Julian Katz-Samuels , Julia Nakhleh , Robert Nowak , Yixuan Li

Deep Learning models possess two key traits that, in combination, make their use in the real world a risky prospect. One, they do not typically generalize well outside of the distribution for which they were trained, and two, they tend to…

Machine Learning · Computer Science 2021-09-29 Jonathan S. Kent , Bo Li

Out-of-distribution (OOD) detection aims to detect test samples outside the training category space, which is an essential component in building reliable machine learning systems. Existing reviews on OOD detection primarily focus on method…

Machine Learning · Computer Science 2025-08-05 Shuo Lu , Yingsheng Wang , Lijun Sheng , Lingxiao He , Aihua Zheng , Jian Liang

Detecting out-of-distribution (OOD) inputs during the inference stage is crucial for deploying neural networks in the real world. Previous methods commonly relied on the output of a network derived from the highly activated feature map. In…

Computer Vision and Pattern Recognition · Computer Science 2023-03-03 Yeonguk Yu , Sungho Shin , Seongju Lee , Changhyun Jun , Kyoobin Lee
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