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Reinforcement Learning (RL) applied in healthcare can lead to unsafe medical decisions and treatment, such as excessive dosages or abrupt changes, often due to agents overlooking common-sense constraints. Consequently, Constrained…

Machine Learning · Computer Science 2024-10-15 Nan Fang , Guiliang Liu , Wei Gong

Patient-reported outcomes (PROs) directly collected from cancer patients being treated with radiation therapy play a vital role in assisting clinicians in counseling patients regarding likely toxicities. Precise prediction and evaluation of…

Machine Learning · Computer Science 2024-11-19 Yang Yan , Zhong Chen , Cai Xu , Xinglei Shen , Jay Shiao , John Einck , Ronald C Chen , Hao Gao

Recurrent exacerbations remain a common yet preventable outcome for many children with asthma. Machine learning (ML) algorithms using electronic medical records (EMR) could allow accurate identification of children at risk for exacerbations…

Monitoring awkward postures is a proactive prevention for Musculoskeletal Disorders (MSDs)in construction. Machine Learning (ML) models have shown promising results for posture recognition from Wearable Sensors. However, further…

Computer Vision and Pattern Recognition · Computer Science 2020-08-05 Junqi Zhao , Esther Obonyo

Background and Objective: Non-invasively predicting the risk of cancer metastasis before surgery plays an essential role in determining optimal treatment methods for cancer patients (including who can benefit from neoadjuvant chemotherapy).…

Randomized controlled trials (RCTs) are the gold standard for assessing drug safety and efficacy. However, RCTs have some drawbacks which have led to the use of single-arm studies to make certain internal drug development and regulatory…

Adversarial machine learning (AML) studies the adversarial phenomenon of machine learning, which may make inconsistent or unexpected predictions with humans. Some paradigms have been recently developed to explore this adversarial phenomenon…

Machine Learning · Computer Science 2024-01-05 Baoyuan Wu , Zihao Zhu , Li Liu , Qingshan Liu , Zhaofeng He , Siwei Lyu

The estimation of individual treatment effects (ITE) focuses on predicting the outcome changes that result from a change in treatment. A fundamental challenge in observational data is that while we need to infer outcome differences under…

Machine Learning · Computer Science 2025-12-23 Zichuan Lin , Xiaokai Huang , Jiate Liu , Yuxuan Han , Jia Chen , Xiapeng Wu , Deheng Ye

New discoveries in chemistry and materials science, with increasingly expanding volume of requisite knowledge and experimental workload, provide unique opportunities for machine learning (ML) to take critical roles in accelerating research…

Debiased machine learning (DML) offers an attractive way to estimate treatment effects in observational settings, where identification of causal parameters requires a conditional independence or unconfoundedness assumption, since it allows…

Econometrics · Economics 2022-06-16 Victor Quintas-Martinez

In this paper, we explore the possibility to apply machine learning to make diagnostic predictions using discomfort drawings. A discomfort drawing is an intuitive way for patients to express discomfort and pain related symptoms. These…

Machine Learning · Computer Science 2016-09-14 Cheng Zhang , Hedvig Kjellstrom , Carl Henrik Ek , Bo C. Bertilson

Causal machine learning (ML) offers flexible, data-driven methods for predicting treatment outcomes including efficacy and toxicity, thereby supporting the assessment and safety of drugs. A key benefit of causal ML is that it allows for…

Objective: To improve prediction of Chronic Kidney Disease (CKD) progression to End Stage Renal Disease (ESRD) using machine learning (ML) and deep learning (DL) models applied to an integrated clinical and claims dataset of varying…

Quantitative Methods · Quantitative Biology 2025-05-06 Yubo Li , Rema Padman

Machine learning is used in medicine to support physicians in examination, diagnosis, and predicting outcomes. One of the most dynamic area is the usage of patient generated health data from intensive care units. The goal of this paper is…

We combine two recently proposed nonparametric difference-in-differences methods, extending them to enable the examination of treatment effect heterogeneity in the staggered adoption setting using machine learning. The proposed method,…

Econometrics · Economics 2023-10-19 Julia Hatamyar , Noemi Kreif , Rudi Rocha , Martin Huber

Appropriate antithrombotic therapy for patients with atrial fibrillation (AF) requires assessment of ischemic stroke and bleeding risks. However, risk stratification schemas such as CHA2DS2-VASc and HAS-BLED have modest predictive capacity…

As machine learning (ML)-based decision support tools proliferate in clinical practice, understanding how clinicians integrate personalized ML predictions alongside randomized controlled trial (RCT) evidence is critical. We designed a…

Human-Computer Interaction · Computer Science 2026-05-19 Zeshan Hussain , Barbara D. Lam , Fernando A. Acosta-Perez , Irbaz Bin Riaz , Maia Jacobs , Andrew J. Yee , David Sontag

Machine Learning (ML) has emerged as a promising approach in healthcare, outperforming traditional statistical techniques. However, to establish ML as a reliable tool in clinical practice, adherence to best practices regarding data…

Image and Video Processing · Electrical Eng. & Systems 2023-09-15 Rosanna Turrisi , Alessandro Verri , Annalisa Barla

We investigate a bias-corrected machine learning (ML) strategy for estimating traces of the inverse Dirac operator, $\text{Tr}\, M^{-n}$ ($n=1,2,3,4$), motivated by the need for higher-order cumulants of the chiral condensate near the…

High Energy Physics - Lattice · Physics 2026-02-26 Benjamin J. Choi , Hiroshi Ohno , Akio Tomiya

Instrumental variable (IV) methods are widely used to adjust for the bias in estimating treatment effects caused by unmeasured confounders in observational studies. In this manuscript, we provide empirical and theoretical evidence that the…

Methodology · Statistics 2015-03-04 Ashkan Ertefaie , Dylan Small , James H. Flory , Sean Hennessy