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Segment Anything Model (SAM) is a foundation model for semantic segmentation and shows excellent generalization capability with the prompts. In this empirical study, we investigate the robustness and zero-shot generalizability of the SAM in…

Image and Video Processing · Electrical Eng. & Systems 2023-05-01 An Wang , Mobarakol Islam , Mengya Xu , Yang Zhang , Hongliang Ren

Foundation models such as Segment Anything Model 3 (SAM3) enable flexible text-guided medical image segmentation, yet their predictions remain highly sensitive to prompt formulation. Even semantically equivalent descriptions can yield…

Computer Vision and Pattern Recognition · Computer Science 2026-03-09 Yonghuang Wu , Zhenyang Liang , Wenwen Zeng , Xuan Xie , Jinhua Yu

Foundation models have taken over natural language processing and image generation domains due to the flexibility of prompting. With the recent introduction of the Segment Anything Model (SAM), this prompt-driven paradigm has entered image…

Image and Video Processing · Electrical Eng. & Systems 2023-04-13 Saikat Roy , Tassilo Wald , Gregor Koehler , Maximilian R. Rokuss , Nico Disch , Julius Holzschuh , David Zimmerer , Klaus H. Maier-Hein

The Segment Anything Model (SAM) can achieve satisfactory segmentation performance under high-quality box prompts. However, SAM's robustness is compromised by the decline in box quality, limiting its practicality in clinical reality. In…

Computer Vision and Pattern Recognition · Computer Science 2024-08-01 Yuhao Huang , Xin Yang , Han Zhou , Yan Cao , Haoran Dou , Fajin Dong , Dong Ni

The Segment Anything Model (SAM) and CLIP are remarkable vision foundation models (VFMs). SAM, a prompt driven segmentation model, excels in segmentation tasks across diverse domains, while CLIP is renowned for its zero shot recognition…

Computer Vision and Pattern Recognition · Computer Science 2024-05-01 Sidra Aleem , Fangyijie Wang , Mayug Maniparambil , Eric Arazo , Julia Dietlmeier , Guenole Silvestre , Kathleen Curran , Noel E. O'Connor , Suzanne Little

Segment Anything Model (SAM), a prompt-driven foundation model for natural image segmentation, has demonstrated impressive zero-shot performance. However, SAM does not work when directly applied to medical image segmentation, since SAM…

Computer Vision and Pattern Recognition · Computer Science 2025-03-25 Bin Xie , Hao Tang , Bin Duan , Dawen Cai , Yan Yan , Gady Agam

Recently, Segment Anything Model (SAM) has demonstrated strong generalizability in various instance segmentation tasks. However, its performance is severely dependent on the quality of manual prompts. In addition, the RGB images that…

Computer Vision and Pattern Recognition · Computer Science 2026-02-09 Yihan Shang , Wei Wang , Chao Huang , Xinghui Dong

Segment Anything Model (SAM) has demonstrated impressive zero-shot performance and brought a range of unexplored capabilities to natural image segmentation tasks. However, as a very important branch of image segmentation, the performance of…

Computer Vision and Pattern Recognition · Computer Science 2025-02-04 Bin Xie , Hao Tang , Dawen Cai , Yan Yan , Gady Agam

The Segment Anything Model (SAM) serves as a fundamental model for semantic segmentation and demonstrates remarkable generalization capabilities across a wide range of downstream scenarios. In this empirical study, we examine SAM's…

Image and Video Processing · Electrical Eng. & Systems 2023-08-15 An Wang , Mobarakol Islam , Mengya Xu , Yang Zhang , Hongliang Ren

The segment anything model (SAM) was released as a foundation model for image segmentation. The promptable segmentation model was trained by over 1 billion masks on 11M licensed and privacy-respecting images. The model supports zero-shot…

Parotid gland lesion segmentation is essential for the treatment of parotid gland diseases. However, due to the variable size and complex lesion boundaries, accurate parotid gland lesion segmentation remains challenging. Recently, the…

Computer Vision and Pattern Recognition · Computer Science 2025-08-14 Zhongyuan Wu , Chuan-Xian Ren , Yu Wang , Xiaohua Ban , Jianning Xiao , Xiaohui Duan

Leveraging the extensive training data from SA-1B, the Segment Anything Model (SAM) demonstrates remarkable generalization and zero-shot capabilities. However, as a category-agnostic instance segmentation method, SAM heavily relies on prior…

Computer Vision and Pattern Recognition · Computer Science 2023-11-30 Keyan Chen , Chenyang Liu , Hao Chen , Haotian Zhang , Wenyuan Li , Zhengxia Zou , Zhenwei Shi

In digital pathology, precise nuclei segmentation is pivotal yet challenged by the diversity of tissue types, staining protocols, and imaging conditions. Recently, the segment anything model (SAM) revealed overwhelming performance in…

Image and Video Processing · Electrical Eng. & Systems 2024-02-27 Zhen Chen , Qing Xu , Xinyu Liu , Yixuan Yuan

Recent advancements in large foundation models have shown promising potential in the medical industry due to their flexible prompting capability. One such model, the Segment Anything Model (SAM), a prompt-driven segmentation model, has…

Computer Vision and Pattern Recognition · Computer Science 2023-08-16 Qi Wu , Yuyao Zhang , Marawan Elbatel

The Segment Anything Model (SAM) has revolutionized interactive segmentation through spatial prompting. While existing work primarily focuses on automating prompts in various settings, real-world annotation workflows involve iterative…

Computer Vision and Pattern Recognition · Computer Science 2026-03-12 Prithwijit Chowdhury , Mohit Prabhushankar , Ghassan AlRegib

Although new vision foundation models such as Segment Anything Model 2 (SAM2) have significantly enhanced zero-shot image segmentation capabilities, reliance on human-provided prompts poses significant challenges in adapting SAM2 to medical…

Computer Vision and Pattern Recognition · Computer Science 2025-06-25 Yang Xing , Jiong Wu , Yuheng Bu , Kuang Gong

Segmentation is a fundamental task in computer vision, with prompt-driven methods gaining prominence due to their flexibility. The Segment Anything Model (SAM) excels at point-prompted segmentation, while text-based models, often leveraging…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Suzhe Xu , Jialin Peng , Chengyuan Zhang

Localizing object parts precisely is essential for tasks such as object recognition and robotic manipulation. Recent part segmentation methods require extensive training data and labor-intensive annotations. Segment-Anything Model (SAM) has…

Computer Vision and Pattern Recognition · Computer Science 2025-01-14 S. B. van Rooij , G. J. Burghouts

Large foundation models, known for their strong zero-shot generalization, have excelled in visual and language applications. However, applying them to medical image segmentation, a domain with diverse imaging types and target labels,…

Image and Video Processing · Electrical Eng. & Systems 2024-04-18 Junde Wu , Jiayuan Zhu , Yueming Jin , Min Xu

The Segment Anything Model (SAM) has demonstrated strong performance in image segmentation of natural scene images. However, its effectiveness diminishes markedly when applied to specific scientific domains, such as Scanning Probe…

Computer Vision and Pattern Recognition · Computer Science 2024-10-17 Yao Shen , Ziwei Wei , Chunmeng Liu , Shuming Wei , Qi Zhao , Kaiyang Zeng , Guangyao Li