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Clinical event sequences consist of hundreds of clinical events that represent records of patient care in time. Developing accurate predictive models of such sequences is of a great importance for supporting a variety of models for…

Machine Learning · Computer Science 2023-08-23 Jeong Min Lee , Milos Hauskrecht

Electronic Health Records (EHRs) contain rich temporal dynamics that conventional encoding approaches fail to adequately capture. While Large Language Models (LLMs) show promise for EHR modeling, they struggle to reason about sequential…

Artificial Intelligence · Computer Science 2025-10-01 Zekai Chen , Arda Pekis , Kevin Brown

Finding interdependency relations between (possibly multivariate) time series provides valuable knowledge about the processes that generate the signals. Information theory sets a natural framework for non-parametric measures of several…

Information Theory · Computer Science 2016-02-09 German Gomez-Herrero , Wei Wu , Kalle Rutanen , Miguel C. Soriano , Gordon Pipa , Raul Vicente

Electronic Healthcare Records contain large volumes of unstructured data, including extensive free text. Yet this source of detailed information often remains under-used because of a lack of methodologies to extract interpretable content in…

Computation and Language · Computer Science 2018-07-10 M. Tarik Altuncu , Erik Mayer , Sophia N. Yaliraki , Mauricio Barahona

Temporal event data are collected across a broad range of domains, and a variety of visual analytics techniques have been developed to empower analysts working with this form of data. These techniques generally display aggregate statistics…

Human-Computer Interaction · Computer Science 2019-11-13 David Gotz , Jonathan Zhang , Wenyuan Wang , Joshua Shrestha , David Borland

Longitudinal health agents must reason across multi-source trajectories that combine continuous device streams, sparse clinical exams, and episodic life events - yet evaluating them is hard: real-world data cannot be released at scale, and…

Artificial Intelligence · Computer Science 2026-04-06 Chao Li , Cailiang Liu , Ang Gao , Kexin Deng , Shu Zhang , Langping Xu , Xiaotong Shi , Xionghao Ding , Jian Pei , Xun Jiang

Functional data is a powerful tool for capturing and analyzing complex patterns and relationships in a variety of fields, allowing for more precise modeling, visualization, and decision-making. For example, in healthcare, functional data…

Methodology · Statistics 2023-04-26 Xiyuan Gao , Jiayi Wang , Guanyu Hu , Jianguo Sun

By adequate employing of complex event processing (CEP), valuable information can be extracted from the underlying complex system and used in controlling and decision situations. An example application area is management of IT systems for…

Software Engineering · Computer Science 2012-08-02 Istvan David

This study proposes a Transformer-based longitudinal modeling method to address challenges in clinical risk classification with heterogeneous Electronic Health Record (EHR) data, including irregular temporal patterns, large modality…

Machine Learning · Computer Science 2025-11-07 Anzhuo Xie , Wei-Chen Chang

This paper presents LLM4ES, a novel framework that exploits large pre-trained language models (LLMs) to derive user embeddings from event sequences. Event sequences are transformed into a textual representation, which is subsequently used…

Information Retrieval · Computer Science 2025-12-18 Aleksei Shestov , Omar Zoloev , Maksim Makarenko , Mikhail Orlov , Egor Fadeev , Ivan Kireev , Andrey Savchenko

Temporal point processes (TPPs) are crucial for analyzing events over time and are widely used in fields such as finance, healthcare, and social systems. These processes are particularly valuable for understanding how events unfold over…

Artificial Intelligence · Computer Science 2026-01-06 Lili Chen , Wensheng Gan , Shuang Liang , Philip S. Yu

Generative models can produce synthetic patient records for analytical tasks when real data is unavailable or limited. However, current methods struggle with adhering to domain-specific knowledge and removing invalid data. We present…

Machine Learning · Computer Science 2023-12-22 Brandon Theodorou , Shrusti Jain , Cao Xiao , Jimeng Sun

Ensemble modeling has been widely used to solve complex problems as it helps to improve overall performance and generalization. In this paper, we propose a novel TemporalAugmenter approach based on ensemble modeling for augmenting the…

Machine Learning · Computer Science 2024-01-17 Nelly Elsayed , Constantinos L. Zekios , Navid Asadizanjani , Zag ElSayed

Data-driven models have demonstrated state-of-the-art performance in inferring the temporal ordering of events in text. However, these models often overlook explicit temporal signals, such as dates and time windows. Rule-based methods can…

Computation and Language · Computer Science 2019-06-21 Tanya Goyal , Greg Durrett

The widespread adoption of electronic health records (EHRs) enables the acquisition of heterogeneous clinical data, spanning lab tests, vital signs, medications, and procedures, which offer transformative potential for artificial…

Signal Processing · Electrical Eng. & Systems 2026-03-17 Mingcheng Zhu , Yu Liu , Zhiyao Luo , Tingting Zhu

Extracting and visualizing informative insights from temporal event sequences becomes increasingly difficult when data volume and variety increase. Besides dealing with high event type cardinality and many distinct sequences, it can be…

Human-Computer Interaction · Computer Science 2017-10-18 Andreas Mathisen , Kaj Grønbæk

Causal phenomena associated with rare events occur across a wide range of engineering problems, such as risk-sensitive safety analysis, accident analysis and prevention, and extreme value theory. However, current methods for causal…

Machine Learning · Statistics 2023-07-19 Chih-Yuan Chiu , Kshitij Kulkarni , Shankar Sastry

Digital monitoring studies collect real-time high frequency data via mobile sensors in the subjects' natural environment. This data can be used to model the impact of changes in physiology on recurrent event outcomes such as smoking, drug…

Methodology · Statistics 2022-04-15 Walter Dempsey

The complexity and heterogeneity of data in many real-world applications pose significant challenges for traditional machine learning and signal processing techniques. For instance, in medicine, effective analysis of diverse physiological…

Machine Learning · Computer Science 2024-08-16 Nimeesha Chan , Felix Parker , William Bennett , Tianyi Wu , Mung Yao Jia , James Fackler , Kimia Ghobadi

In applications such as biomedical studies, epidemiology, and social sciences, recurrent events often co-occur with longitudinal measurements and a terminal event, such as death. Therefore, jointly modeling longitudinal measurements,…

Machine Learning · Statistics 2024-04-08 Zhiyue Zhang , Yao Zhao , Yanxun Xu