Related papers: Inferring High-Level Events from Timestamped Data:…
This report describes a minimalistic set of methods engineered to anchor clinical events onto a temporal space. Specifically, we describe methods to extract clinical events (e.g., Problems, Treatments and Tests), temporal expressions (i.e.,…
In high-stakes systems such as healthcare, it is critical to understand the causal reasons behind unusual events, such as sudden changes in patient's health. Unveiling the causal reasons helps with quick diagnoses and precise treatment…
Motivation: Biomedical event detection is fundamental for information extraction in molecular biology and biomedical research. The detected events form the central basis for comprehensive biomedical knowledge fusion, facilitating the…
Process mining methods often analyze processes in terms of the individual end-to-end process runs. Process behavior, however, may materialize as a general state of many involved process components, which can not be captured by looking at…
With the availability of massive amounts of data from electronic health records and registry databases, incorporating time-varying patient information to improve risk prediction has attracted great attention. To exploit the growing amount…
Knowing the state of our health at every moment in time is critical for advances in health science. Using data obtained outside an episodic clinical setting is the first step towards building a continuous health estimation system. In this…
Temporal Point Processes (TPP) play an important role in predicting or forecasting events. Although these problems have been studied extensively, predicting multiple simultaneously occurring events can be challenging. For instance, more…
Understanding natural language involves recognizing how multiple event mentions structurally and temporally interact with each other. In this process, one can induce event complexes that organize multi-granular events with temporal order…
This work develops a flexible inferential framework for nonparametric causal inference in time-to-event settings, based on stochastic interventions defined through multiplicative scaling of the intensity governing an intermediate event…
The availability of a large amount of electronic health records (EHR) provides huge opportunities to improve health care service by mining these data. One important application is clinical endpoint prediction, which aims to predict whether…
Adaptive enrichment allows for pre-defined patient subgroups of interest to be investigated throughout the course of a clinical trial. Many trials which measure a long-term time-to-event endpoint often also routinely collect repeated…
Most existing time-to-event methods focus on either single-event or competing-risks settings, leaving multi-event scenarios relatively underexplored. In many healthcare applications, for example, a patient may experience multiple clinical…
Humans learn from the occurrence of events in a different place and time to predict similar trajectories of events. We define Loosely Decoupled Timeseries (LDT) phenomena as two or more events that could happen in different places and…
We propose a new class of waveform foundation models that departs from conventional sequence based representations by modeling physiological time series as realizations of latent event processes. Rather than treating signals as collections…
Modern health data science applications leverage abundant molecular and electronic health data, providing opportunities for machine learning to build statistical models to support clinical practice. Time-to-event analysis, also called…
Timed Transition Models (TTMs) are event-based descriptions for modelling, specifying, and verifying discrete real-time systems. An event can be spontaneous, fair, or timed with specified bounds. TTMs have a textual syntax, an operational…
Events across a timeline are a common data representation, seen in different temporal modalities. Individual atomic events can occur in a certain temporal ordering to compose higher level composite events. Examples of a composite event are…
With the recent availability of Electronic Health Records (EHR) and great opportunities they offer for advancing medical informatics, there has been growing interest in mining EHR for improving quality of care. Disease diagnosis due to its…
Time-to-event endpoints are central to evaluate treatment efficacy across many disease areas. Many trial protocols include interim analyses within group-sequential designs that control type I error via spending functions or boundary…
Complex systems display emergent phenomena that vary significantly across spatial and temporal scales. These variations originate from fine-grained system processes, yet arriving at macroscopic dynamics from micro-level data -- particularly…