English
Related papers

Related papers: TorchGWAS : GPU-accelerated GWAS for thousands of …

200 papers

Dynamically typed languages such as JavaScript and Python have emerged as the most popular programming languages in use. Important benefits can accrue from including type annotations in dynamically typed programs. This approach to gradual…

Programming Languages · Computer Science 2021-11-16 Fangke Ye , Jisheng Zhao , Vivek Sarkar

Analyzing non-compilable C/C++ submodules without a resolved build environment remains a critical bottleneck for industrial software evolution. Traditional static analysis tools often fail in these scenarios due to their reliance on…

Software Engineering · Computer Science 2026-02-20 Jaid Monwar Chowdhury , Ahmad Farhan Shahriar Chowdhury , Humayra Binte Monwar , Mahmuda Naznin

Large-scale observational health databases are increasingly popular for conducting comparative effectiveness and safety studies of medical products. However, increasing number of patients poses computational challenges when fitting survival…

Computation · Statistics 2023-10-26 Jianxiao Yang , Martijn J. Schuemie , Xiang Ji , Marc A. Suchard

Approximate Nearest Neighbor Search (ANNS) has become fundamental to modern deep learning applications, having gained particular prominence through its integration into recent generative models that work with increasingly complex datasets…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-03-28 Yuntao Gui , Peiqi Yin , Xiao Yan , Chaorui Zhang , Weixi Zhang , James Cheng

Software faults are commonly occurred due to interactions between one or more input parameters in complex software systems. Software test design techniques can be implemented to ensure the quality of the developed software. Exhaustive…

Software Engineering · Computer Science 2021-08-03 Khin Maung Htay , Rozmie Razif Othman , Amiza Amir , Hasneeza Liza Zakaria , Nuraminah Ramli

Graph partitioning, a well studied problem of parallel computing has many applications in diversified fields such as distributed computing, social network analysis, data mining and many other domains. In this paper, we introduce FGPGA, an…

Neural and Evolutionary Computing · Computer Science 2014-11-18 Md. Lisul Islam , Novia Nurain , Swakkhar Shatabda , M Sohel Rahman

We present GNNAutoScale (GAS), a framework for scaling arbitrary message-passing GNNs to large graphs. GAS prunes entire sub-trees of the computation graph by utilizing historical embeddings from prior training iterations, leading to…

Machine Learning · Computer Science 2021-06-11 Matthias Fey , Jan E. Lenssen , Frank Weichert , Jure Leskovec

Large-scale molecular dynamics simulations with high accuracy have been increasingly popular for their capability to bridge the gap between atomistic modeling and mesoscale phenomena. Both machine learning potentials and enhanced sampling…

Computational Physics · Physics 2026-03-24 Haoting Zhang , Qiuhan Jia , Zhennan Zhang , Yijie Zhu , Zhongwei Zhang , Junjie Wang , Jiuyang Shi , Zheyong Fan , Jian Sun

Graph Random Walks (GRWs) offer efficient approximations of key graph properties and have been widely adopted in many applications. However, GRW workloads are notoriously difficult to accelerate due to their strong data dependencies,…

Hardware Architecture · Computer Science 2026-01-19 Hongshi Tan , Yao Chen , Xinyu Chen , Qizhen Zhang , Cheng Chen , Weng-Fai Wong , Bingsheng He

FPGA-based hardware accelerators for convolutional neural networks (CNNs) have obtained great attentions due to their higher energy efficiency than GPUs. However, it is challenging for FPGA-based solutions to achieve a higher throughput…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-06-09 Yixing Li , Zichuan Liu , Kai Xu , Hao Yu , Fengbo Ren

In this work we propose an accelerated stochastic learning system for very large-scale applications. Acceleration is achieved by mapping the training algorithm onto massively parallel processors: we demonstrate a parallel, asynchronous GPU…

Machine Learning · Computer Science 2017-02-24 Thomas Parnell , Celestine Dünner , Kubilay Atasu , Manolis Sifalakis , Haris Pozidis

The development of large language models (LLMs) has been instrumental in advancing state-of-the-art natural language processing applications. Training LLMs with billions of parameters and trillions of tokens require sophisticated…

Advances in DNA sequencing technology have stimulated the development of algorithms and tools for processing very large collections of short strings (reads). Short-read alignment and assembly are among the most well-studied problems. Many…

Genomics · Quantitative Biology 2014-01-30 Chi-Man Liu , Ruibang Luo , Tak-Wah Lam

While it is well-known and acknowledged that the performance of graph algorithms is heavily dependent on the input data, there has been surprisingly little research to quantify and predict the impact the graph structure has on performance.…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-08-04 Merijn Verstraaten , Ana Lucia Varbanescu , Cees de Laat

Large scale studies of group differences in healthy controls and patients and screenings for early stage disease prevention programs require processing and analysis of extensive multisubject datasets. Complexity of the task increases even…

Computer Vision and Pattern Recognition · Computer Science 2017-11-02 Alex Fedorov , Eswar Damaraju , Vince Calhoun , Sergey Plis

Polygenic risk scores (PRSs) aggregate genetic effect estimates to predict disease susceptibility, yet clinical deployment often exposes raw genotype data to third-party compute infrastructure. Prior homomorphic-encryption approaches, still…

Genomics · Quantitative Biology 2026-05-22 Kimon Antonios Provatas , Christos Galanopoulos , Ilias Georgakopoulos-Soares

In recent years, Approximate Nearest Neighbor Search (ANNS) has played a pivotal role in modern search and recommendation systems, especially in emerging LLM applications like Retrieval-Augmented Generation. There is a growing exploration…

Information Retrieval · Computer Science 2024-11-07 Yiping Sun , Yang Shi , Jiaolong Du

Genome-wide association studies (GWAS) have been widely used to examine the association between single nucleotide polymorphisms (SNPs) and complex traits, where both the sample size n and the number of SNPs p can be very large. Recently,…

Methodology · Statistics 2019-03-05 Bingxin Zhao , Hongtu Zhu

Efficiently finding subgraph embeddings in large graphs is crucial for many application areas like biology and social network analysis. Set intersections are the predominant and most challenging aspect of current join-based subgraph query…

Databases · Computer Science 2024-02-28 Jonas Dann , Tobias Götz , Daniel Ritter , Jana Giceva , Holger Fröning

Reliable evaluation of anomaly detection methods in multivariate time series remains an open challenge, largely due to the limitations of existing benchmark datasets. Current resources often lack fine-grained anomaly annotations, do not…

Artificial Intelligence · Computer Science 2026-04-17 Pierre Lotte , André Péninou , Olivier Teste