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Dynamic treatment regimes (DTRs) are critical to precision medicine, optimizing long-term outcomes through personalized, real-time decision-making in evolving clinical contexts, but require careful supervision for unsafe treatment risks.…

Machine Learning · Computer Science 2025-06-10 Yishan Shen , Yuyang Ye , Hui Xiong , Yong Chen

Clinical notes are often stored in unstructured or semi-structured formats after extraction from electronic medical record (EMR) systems, which complicates their use for secondary analysis and downstream clinical applications. Reliable…

Computation and Language · Computer Science 2025-12-30 Risha Surana , Adrian Law , Sunwoo Kim , Rishab Sridhar , Angxiao Han , Peiyu Hong

We present Eir-8B, a large language model with 8 billion parameters, specifically designed to enhance the accuracy of handling medical tasks in the Thai language. This model focuses on providing clear and easy-to-understand answers for both…

Computation and Language · Computer Science 2024-09-17 Yutthakorn Thiprak , Rungtam Ngodngamthaweesuk , Songtam Ngodngamtaweesuk

Real-world clinical text-to-SQL requires reasoning over heterogeneous EHR tables, temporal windows, and patient-similarity cohorts to produce executable queries. We introduce CLINSQL, a benchmark of 633 expert-annotated tasks on MIMIC-IV…

Computation and Language · Computer Science 2026-01-16 Yifei Shen , Yilun Zhao , Justice Ou , Tinglin Huang , Arman Cohan

Recent advances in large language models (LLMs) have predominantly focused on maximizing accuracy and reasoning capabilities, often overlooking crucial computational efficiency considerations. While this approach has yielded impressive…

Machine Learning · Computer Science 2024-12-24 Marwan AbdElhameed , Pavly Halim

The ability of large language models (LLMs) to follow natural language instructions with human-level fluency suggests many opportunities in healthcare to reduce administrative burden and improve quality of care. However, evaluating LLMs on…

In the past decade, the healthcare industry has made significant advances in the digitization of patient information. However, a lack of interoperability among healthcare systems still imposes a high cost to patients, hospitals, and…

Information Retrieval · Computer Science 2019-12-03 Daniel Cotter , V. K. Cody Bumgardner

The development of Electronic Health Records summarization systems has revolutionized patient data management. Previous research advanced this field by adapting Large Language Models for clinical tasks, using diverse datasets to generate…

Computation and Language · Computer Science 2024-10-15 Ruvarashe Madzime , Clement Nyirenda

While the reasoning capabilities of Large Language Models (LLMs) excel in analytical tasks such as mathematics and code generation, their utility for abstractive summarization remains widely assumed but largely unverified. To bridge this…

Computation and Language · Computer Science 2025-12-10 Haohan Yuan , Haopeng Zhang

Monitoring the health status of patients in the Intensive Care Unit (ICU) is a critical aspect of providing superior care and treatment. The availability of large-scale electronic health records (EHR) provides machine learning models with…

Artificial Intelligence · Computer Science 2023-05-05 Jun Wu , Xuesong Ye , Chengjie Mou , Weinan Dai

The growing integration of vision-language models (VLMs) in medical applications offers promising support for diagnostic reasoning. However, current medical VLMs often face limitations in generalization, transparency, and computational…

Computer Vision and Pattern Recognition · Computer Science 2025-06-17 Tan-Hanh Pham , Chris Ngo

Clinical antimicrobial therapy requires the dynamic integration of pathogen profiles,host factors, pharmacological properties of antimicrobials,and the severity of infection. This complexity imposes fundamental limitations on the…

Artificial Intelligence · Computer Science 2025-11-27 Zhe Li , Yehan Qiu , Yujie Chen , Xiang Zhou

Research is a tertiary priority in the EHR, where the priorities are patient care and billing. Because of this, the data is not standardized or formatted in a manner easily adapted to machine learning approaches. Data may be missing for a…

Machine Learning · Computer Science 2017-07-25 Brett K. Beaulieu-Jones

As medical large language models (LLMs) become increasingly integrated into clinical workflows, concerns around alignment robustness, and safety are escalating. Prior work on model extraction has focused on classification models or…

Machine Learning · Computer Science 2025-12-11 Sohely Jahan , Ruimin Sun

Large language models (LLMs) excel in many natural language tasks, yet they struggle with complex mathemat-ical problem-solving, particularly in symbolic reasoning and maintaining consistent output. This study evalu-ates 10 LLMs with 7 to 8…

Machine Learning · Computer Science 2025-01-29 Evgenii Evstafev

Accurate survival prediction in radiotherapy (RT) is critical for optimizing treatment decisions. This study developed and validated the RT-Surv framework, which integrates general-domain, open-source large language models (LLMs) to…

BACKGROUND: Atrial fibrillation (AF), the most common arrhythmia, is linked to high morbidity and mortality. In a fast-evolving AF rhythm control treatment era, predicting AF recurrence after its onset may be crucial to achieve the optimal…

Brief hospital course (BHC) summaries are clinical documents that summarize a patient's hospital stay. While large language models (LLMs) depict remarkable capabilities in automating real-world tasks, their capabilities for healthcare…

Embedding models have become essential for retrieval-augmented generation (RAG) tasks, semantic clustering, and text re-ranking. But despite their growing use, many of these come with notable limitations. For example, Jina fails to capture…

Information Retrieval · Computer Science 2025-05-21 Anand Selvadurai , Jasheen Shaik , Girish Chandrasekar , ShriRadhaKrishnan Balamurugan , Eswara Reddy

Clinician must write a lengthy summary each time a patient is discharged from the hospital. This task is time-consuming due to the sheer number of unique clinical concepts covered in the admission. Identifying and covering salient entities…

Computation and Language · Computer Science 2024-09-30 Griffin Adams , Jason Zucker , Noémie Elhadad