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Predicting future clinical outcomes from electronic health records (EHR) remains challenging due to the complexity and heterogeneity of patient data. LLMs have shown strong potential for such predictive tasks, yet existing approaches mainly…

Computation and Language · Computer Science 2026-05-05 Yushi Cao , Yiming Chen , Hongchao Jiang , Hung-yi Lee , Robby T. Tan

Instruction tuning has become essential for adapting large language models (LLMs) to follow domain-specific prompts. Yet, in specialized fields such as medicine, the scarcity of high-quality French instruction data limits effective…

Computation and Language · Computer Science 2026-03-10 Ikram Belmadani , Oumaima El Khettari , Pacôme Constant dit Beaufils , Benoit Favre , Richard Dufour

Summarizing consumer health questions (CHQs) can ease communication in healthcare, but unfaithful summaries that misrepresent medical details pose serious risks. We propose a framework that combines TextRank-based sentence extraction and…

Computation and Language · Computer Science 2025-11-17 Ajwad Abrar , Nafisa Tabassum Oeshy , Prianka Maheru , Farzana Tabassum , Tareque Mohmud Chowdhury

Large Language Models (LLMs) have demonstrated significant potential in transforming clinical applications. In this study, we investigate the efficacy of four techniques in adapting LLMs for clinical use-cases: continuous pretraining,…

Irregular sampling and high missingness are intrinsic challenges in modeling time series derived from electronic health records (EHRs),where clinical variables are measured at uneven intervals depending on workflow and intervention timing.…

Machine Learning · Computer Science 2025-09-29 Jeong Eul Kwon , Joo Heung Yoon , Hyo Kyung Lee

There is an increasing interest in developing artificial intelligence (AI) systems to process and interpret electronic health records (EHRs). Natural language processing (NLP) powered by pretrained language models is the key technology for…

Background: Clinical documentation represents a significant burden for healthcare providers, with physicians spending up to 2 hours daily on administrative tasks. Recent advances in large language models (LLMs) offer promising solutions,…

Computation and Language · Computer Science 2025-07-08 Johnson Thomas , Ayush Mudgal , Wendao Liu , Nisten Tahiraj , Zeeshaan Mohammed , Dhruv Diddi

Clinical reports are often fragmented across healthcare institutions because privacy regulations and data silos limit direct information sharing. When patients seek care at a different hospital, they often carry paper or scanned reports…

Computation and Language · Computer Science 2026-05-12 Yu Wang , Yingyun Li , Ying Qin , Haiyang Qian

While there has been recent progress in abstractive summarization as applied to different domains including news articles, scientific articles, and blog posts, the application of these techniques to clinical text summarization has been…

Computation and Language · Computer Science 2022-04-05 Amanuel Alambo , Tanvi Banerjee , Krishnaprasad Thirunarayan , Mia Cajita

Background: Data collected in controlled settings typically results in high-quality datasets. However, in real-world applications, the quality of data collection is often compromised. It is well established that the quality of a dataset…

Computation and Language · Computer Science 2025-02-14 Tabinda Sarwar , Antonio Jose Jimeno Yepes , Lawrence Cavedon

White matter hyperintensities (WMH) and ischaemic stroke lesions (ISL) are imaging features associated with cerebral small vessel disease (SVD) that are visible on brain magnetic resonance imaging (MRI) scans. The development and validation…

Computer Vision and Pattern Recognition · Computer Science 2026-01-29 Jesse Phitidis , Alison Q. Smithard , William N. Whiteley , Joanna M. Wardlaw , Miguel O. Bernabeu , Maria Valdés Hernández

Recent advances in Large Language Models (LLMs) have led to remarkable progresses in medical consultation. However, existing medical LLMs overlook the essential role of Electronic Health Records (EHR) and focus primarily on diagnosis…

Artificial Intelligence · Computer Science 2025-06-26 Weijieying Ren , Tianxiang Zhao , Lei Wang , Tianchun Wang , Vasant Honavar

Large language models (LLMs) excel at clinical information extraction but their computational demands limit practical deployment. Knowledge distillation--the process of transferring knowledge from larger to smaller models--offers a…

Computation and Language · Computer Science 2025-01-03 Karthik S. Vedula , Annika Gupta , Akshay Swaminathan , Ivan Lopez , Suhana Bedi , Nigam H. Shah

While large language models show promise in medical applications, achieving expert-level clinical reasoning remains challenging due to the need for both accurate answers and transparent reasoning processes. To address this challenge, we…

Machine Learning · Computer Science 2025-09-22 Chi Liu , Derek Li , Yan Shu , Robin Chen , Derek Duan , Teng Fang , Bryan Dai

Machine learning (ML) promises better clinical decision-making, yet opaque model behavior limits the adoption in healthcare. We propose two novel regularization techniques for ensuring the interpretability of ML models trained on real-world…

Machine Learning · Computer Science 2026-03-24 Salma Rachidi , Aso Bozorgpanah , Eric Fey , Alexander Jung

Large language models (LLMs) show promise for supporting clinicians in diagnostic communication by generating explanations and guidance for patients. Yet their ability to produce outputs that are both understandable and empathetic remains…

Computation and Language · Computer Science 2025-11-04 Jianzhou Yao , Shunchang Liu , Guillaume Drui , Rikard Pettersson , Alessandro Blasimme , Sara Kijewski

With the growing imbalance between limited medical resources and escalating demands, AI-based clinical tasks have become paramount. As a sub-domain, medication recommendation aims to amalgamate longitudinal patient history with medical…

Artificial Intelligence · Computer Science 2023-11-28 Xiang Li , Shunpan Liang , Yulei Hou , Tengfei Ma

Although Large language Model (LLM)-powered information extraction (IE) systems have shown impressive capabilities, current fine-tuning paradigms face two major limitations: high training costs and difficulties in aligning with LLM…

Computation and Language · Computer Science 2025-12-16 Yushen Fang , Jianjun Li , Mingqian Ding , Chang Liu , Xinchi Zou , Wenqi Yang

Foundation models hold promise for transforming AI in healthcare by providing modular components that are easily adaptable to downstream healthcare tasks, making AI development more scalable and cost-effective. Structured EHR foundation…

Security of software supply chains is necessary to ensure that software updates do not contain maliciously injected code or introduce vulnerabilities that may compromise the integrity of critical infrastructure. Verifying the integrity of…

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