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Angle closure glaucoma (ACG) is a more aggressive disease than open-angle glaucoma, where the abnormal anatomical structures of the anterior chamber angle (ACA) may cause an elevated intraocular pressure and gradually lead to glaucomatous…
Purpose: (1) To assess the performance of geometric deep learning (PointNet) in diagnosing glaucoma from a single optical coherence tomography (OCT) 3D scan of the optic nerve head (ONH); (2) To compare its performance to that obtained with…
Glaucoma causes an irreversible damage to retinal nerve fibers which results in vision loss, if undetected in early stage. Therefore, diagnosis of glaucoma in its early stage may prevent further vision loss. In this paper, we propose a…
This study proposes a Transformer-based longitudinal modeling method to address challenges in clinical risk classification with heterogeneous Electronic Health Record (EHR) data, including irregular temporal patterns, large modality…
Glaucoma is a common eye disease that leads to irreversible blindness unless timely detected. Hence, glaucoma detection at an early stage is of utmost importance for a better treatment plan and ultimately saving the vision. The recent…
In this manuscript, we automate the procedure of grading of diabetic retinopathy and macular edema from fundus images using an ensemble of convolutional neural networks. The availability of limited amount of labeled data to perform…
Medical images are generally labeled by multiple experts before the final ground-truth labels are determined. Consensus or disagreement among experts regarding individual images reflects the gradeability and difficulty levels of the image.…
Late diagnosis and high costs are key factors that negatively impact the care of cancer patients worldwide. Although the availability of biological markers for the diagnosis of cancer type is increasing, costs and reliability of tests…
This study investigates the detection and classification of depressive and non-depressive states using deep learning approaches. Depression is a prevalent mental health disorder that substantially affects quality of life, and early…
In this paper, we have proposed a new glaucoma classification approach that employs a wavelet neural network (WNN) on optimally enhanced retinal images features. To avoid tedious and error prone manual analysis of retinal images by…
Diagnosing glaucoma progression is critical for limiting irreversible vision loss. A common method for assessing glaucoma progression uses a longitudinal series of visual fields (VF) acquired at regular intervals. VF data are characterized…
With the advancement of deep learning techniques, an increasing number of methods have been proposed for optic disc and cup (OD/OC) segmentation from the fundus images. Clinically, OD/OC segmentation is often annotated by multiple clinical…
The Convolutional Neural Network (CNN) has shown impressive performance in image classification because of its strong learning capabilities. However, it demands a substantial and balanced dataset for effective training. Otherwise, networks…
GAMMA Challenge is organized to encourage the AI models to screen the glaucoma from a combination of 2D fundus image and 3D optical coherence tomography volume, like the ophthalmologists.
Multiple sclerosis (MS) affects the central nervous system with a wide range of symptoms. MS can, for example, cause pain, changes in mood and fatigue, and may impair a person's movement, speech and visual functions. Diagnosis of MS…
Importance: The prevalence of severe mental illnesses (SMIs) in the United States is approximately 3% of the whole population. The ability to conduct risk screening of SMIs at large scale could inform early prevention and treatment.…
Despite extensive safety assessments of drugs prior to their introduction to the market, certain adverse drug reactions (ADRs) remain undetected. The primary objective of pharmacovigilance is to identify these ADRs (i.e., signals). In…
Glaucoma is a complex group of eye diseases marked by optic nerve damage, commonly linked to elevated intraocular pressure and biomarkers like retinal nerve fiber layer thickness. Understanding how these biomarkers interact is crucial for…
Abnormalities in retinal fundus images may indicate certain pathologies such as diabetic retinopathy, hypertension, stroke, glaucoma, retinal macular edema, venous occlusion, and atherosclerosis, making the study and analysis of retinal…
The optimal treatment strategy of newly diagnosed glioma is strongly influenced by tumour malignancy. Manual non-invasive grading based on MRI is not always accurate and biopsies to verify diagnosis negatively impact overall survival. In…