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Purpose: To develop a deep learning approach to digitally-stain optical coherence tomography (OCT) images of the optic nerve head (ONH). Methods: A horizontal B-scan was acquired through the center of the ONH using OCT (Spectralis) for 1…

Multimodal electronic health record (EHR) data is useful for disease risk prediction based on medical domain knowledge. However, general medical knowledge must be adapted to specific healthcare settings and patient populations to achieve…

Glaucoma is a top cause of irreversible blindness globally, making early detection and longitudinal follow-up pivotal to preventing permanent vision loss. Current screening and progression assessment, however, rely on single tests or…

Schizophrenia (SZ) is a serious mental disorder that could seriously affect the patient's quality of life. In recent years, detection of SZ based on deep learning (DL) using electroencephalogram (EEG) has received increasing attention. In…

Electronic health records (EHR's) are only a first step in capturing and utilizing health-related data - the problem is turning that data into useful information. Models produced via data mining and predictive analysis profile inherited…

The development of automatic tools for early glaucoma diagnosis with color fundus photographs can significantly reduce the impact of this disease. However, current state-of-the-art solutions are not robust to real-world scenarios, providing…

The Gleason score is the most important prognostic marker for prostate cancer patients but suffers from significant inter-observer variability. We developed a fully automated deep learning system to grade prostate biopsies. The system was…

Digitization of histology images and the advent of new computational methods, like deep learning, have helped the automatic grading of colorectal adenocarcinoma cancer (CRA). Present automated CRA grading methods, however, usually use tiny…

The next generation of High Energy Physics (HEP) experiments requires a GRID approach to a distributed computing system and the associated data management: the key concept is the Virtual Organisation (VO), a group of distributed users with…

Hypoglycemia is common and potentially dangerous among those treated for diabetes. Electronic health records (EHRs) are important resources for hypoglycemia surveillance. In this study, we report the development and evaluation of deep…

Automatic evaluation of the retinal fundus image is emerging as one of the most important tools for early detection and treatment of progressive eye diseases like Glaucoma. Glaucoma results to a progressive degeneration of vision and is…

Differences in image quality, lighting conditions, and patient demographics pose challenges to automated glaucoma detection from color fundus photography. Brighteye, a method based on Vision Transformer, is proposed for glaucoma detection…

Objective: (1) To assess whether ONH biomechanics improves prediction of three progressive visual field loss patterns in glaucoma; (2) to use explainable AI to identify strain-sensitive ONH regions contributing to these predictions.…

Acute lymphoblastic leukemia (ALL) is the most malignant form of leukemia and the most common cancer in adults and children. Traditionally, leukemia is diagnosed by analyzing blood and bone marrow smears under a microscope, with additional…

Diabetic retinopathy (DR), a microvascular complication of diabetes and a leading cause of preventable blindness, is projected to affect more than 130 million individuals worldwide by 2030. Early identification is essential to reduce…

Glaucoma is an irreversible ocular disease and is the second leading cause of visual disability worldwide. Slow vision loss and the asymptomatic nature of the disease make its diagnosis challenging. Early detection is crucial for preventing…

Glaucoma causes irreversible vision loss due to damage to the optic nerve, and there is no cure for glaucoma.OCT imaging modality is an essential technique for assessing glaucomatous damage since it aids in quantifying fundus structures. To…

Early detection of melanoma, a potentially lethal type of skin cancer with high prevalence worldwide, improves patient prognosis. In retrospective studies, artificial intelligence (AI) has proven to be helpful for enhancing melanoma…

Electronic health records (EHRs) provide a powerful basis for predicting the onset of health outcomes. Yet EHRs primarily capture in-clinic events and miss aspects of daily behavior and lifestyle containing rich health information. Consumer…

With the advancements in medical artificial intelligence (AI), fundus image classifiers are increasingly being applied to assist in ophthalmic diagnosis. While existing classification models have achieved high accuracy on specific fundus…