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HIV transmission within serodiscordant couples remains a significant public health challenge, particularly in sub-Saharan Africa. Estimating the rate of such infection, alongside the rates of introduction of infection from outside the…

Applications · Statistics 2026-02-05 Irene García Muñoz , Ian Hall , Thomas House

Graphical models are widely used to make inferences concerning interplay in multivariate systems. In many applications, data are collected from multiple related but nonidentical units whose underlying networks may differ but are likely to…

Methodology · Statistics 2014-12-04 Chris J. Oates , Jim Korkola , Joe W. Gray , Sach Mukherjee

We develop a stochastic epidemic model progressing over dynamic networks, where infection rates are heterogeneous and may vary with individual-level covariates. The joint dynamics are modeled as a continuous-time Markov chain such that…

Methodology · Statistics 2021-12-16 Fan Bu , Allison E. Aiello , Alexander Volfovsky , Jason Xu

This paper offers a qualitative insight into the convergence of Bayesian parameter inference in a setup which mimics the modeling of the spread of a disease with associated disease measurements. Specifically, we are interested in the…

Statistics Theory · Mathematics 2022-12-08 Samuel Bronstein , Stefan Engblom , Robin Marin

Spatio-temporal extensions of familiar compartment models for disease transmission incorporating diffusive behavior, or interactions between individuals at separate locations, are explored. The models considered have the character of…

Biological Physics · Physics 2022-06-28 Joseph Rudnick , David Jasnow , Jorge Vinals

Variational inference provides approximations to the computationally intractable posterior distribution in Bayesian networks. A prominent medical application of noisy-or Bayesian network is to infer potential diseases given observed…

Machine Learning · Computer Science 2016-05-23 Yusheng Xie , Nan Du , Wei Fan , Jing Zhai , Weicheng Zhu

Infectious diseases in livestock are well-known to infect multiple hosts and persist through the combination of within- and between-host transmission pathways. Uncertainty remains about the epidemic consequences of the disease being…

Quantitative Methods · Quantitative Biology 2022-01-17 Nicolas C. Cardenas , Abagael L. Sykes , Francisco P. N. Lopes , Gustavo Machado

Mathematical disease modelling has long operated under the assumption that any one infectious disease is caused by one transmissible pathogen spreading among a population. This paradigm has been useful in simplifying the biological reality…

Populations and Evolution · Quantitative Biology 2021-06-02 Blake J. M. Williams , Guillaume St-Onge , Laurent Hébert-Dufresne

Epidemic spread in single-host systems strongly depends on the population's contact network. However, little is known regarding the spread of epidemics across networks representing populations of multiple hosts. We explored cross-species…

Populations and Evolution · Quantitative Biology 2017-12-06 Shai Pilosof , Gili Greenbaum , Boris R. Krasnov , Yuval R. Zelnik

Epidemic models often reflect characteristic features of infectious spreading processes by coupled non-linear differential equations considering different states of health (such as Susceptible, Infected, or Recovered). This compartmental…

Physics and Society · Physics 2021-12-01 Vaiva Vasiliauskaite , Nino Antulov-Fantulin , Dirk Helbing

A deterministic pathogen transmission model based on high-fidelity physics has been developed. The model combines computational fluid dynamics and computational crowd dynamics in order to be able to provide accurate tracing of viral matter…

Numerical Analysis · Mathematics 2022-10-26 Rainald Löhner , Harbir Antil , Juan Marcelo Gimenez , Sergio Idelsohn , Eugenio Oñate

The role of direct cell-to-cell spread in viral infections - where virions spread between host and susceptible cells without needing to be secreted into the extracellular environment - has come to be understood as essential to the dynamics…

Quantitative Methods · Quantitative Biology 2024-05-21 Thomas Williams , James M. McCaw , James Osborne

A widely-used model for determining the long-term health impacts of public health interventions, often called a "multistate lifetable", requires estimates of incidence, case fatality, and sometimes also remission rates, for multiple…

Applications · Statistics 2023-03-23 Christopher Jackson , Belen Zapata-Diomedi , James Woodcock

A class of stochastic vector-borne infectious disease models is derived and studied. The class type is determined by a general nonlinear incidence rate of the disease. The disease spreads in a highly random environment with variability from…

Populations and Evolution · Quantitative Biology 2020-05-05 Divine Wanduku

Human mobility, contact patterns, and their interplay are key aspects of our social behavior that shape the spread of infectious diseases across different regions. In the light of new evidence and data sets about these two elements,…

Physics and Society · Physics 2021-07-26 Wesley Cota , David Soriano-Paños , Alex Arenas , Silvio C. Ferreira , Jesús Gómez-Gardeñes

We study the problem of estimating the origin of an epidemic outbreak -- given a contact network and a snapshot of epidemic spread at a certain time, determine the infection source. Finding the source is important in different contexts of…

Physics and Society · Physics 2014-11-20 Andrey Y. Lokhov , Marc Mézard , Hiroki Ohta , Lenka Zdeborová

In the presence of modeling errors, the mainstream Bayesian methods seldom give a realistic account of uncertainties as they commonly underestimate the inherent variability of parameters. This problem is not due to any misconception in the…

Applications · Statistics 2020-05-19 Omid Sedehi , Costas Papadimitriou , Lambros S. Katafygiotis

There is a rich history of models for the interaction of a biological contagion like influenza with the spread of related information such as an influenza vaccination campaign. Recent work on the spread of interacting contagions on networks…

Physics and Society · Physics 2020-09-02 Laurent Hébert-Dufresne , Dina Mistry , Benjamin M. Althouse

Multiple imputation has become one of the standard methods in drawing inferences in many incomplete data applications. Applications of multiple imputation in relatively more complex settings, such as high-dimensional clustered data, require…

Methodology · Statistics 2025-04-08 Qiushuang Li , Recai Yucel

The transmission dynamics of some infectious diseases is related to the contact structure between individuals in a network. We used five algorithms to generate contact networks with different topological structure but with the same…

Populations and Evolution · Quantitative Biology 2013-08-28 Raul Ossada , José H. H. Grisi-Filho , Fernando Ferreira , Marcos Amaku
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