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One of the major issues in the theoretical modeling of epidemic spreading is the development of methods to control the transmission of an infectious agent. Human behavior plays a fundamental role in the spreading dynamics and can be used to…

In many scenarios, the observational data needed for causal inferences are spread over two data files. In particular, we consider scenarios where one file includes covariates and the treatment measured on one set of individuals, and a…

Methodology · Statistics 2020-09-22 Sharmistha Guha , Jerome P. Reiter , Andrea Mercatanti

Infectious diseases outbreaks are often characterized by a spatial component induced by hosts' distribution, mobility, and interactions. Spatial models that incorporate hosts' movements are being used to describe these processes, to…

Physics and Society · Physics 2012-07-20 Chiara Poletto , Michele Tizzoni , Vittoria Colizza

Early, reliable detection of disease outbreaks is a critical problem today. This paper reports an investigation of the use of causal Bayesian networks to model spatio-temporal patterns of a non-contagious disease (respiratory anthrax…

Applications · Statistics 2012-07-19 Gregory F. Cooper , Denver Dash , John Levander , Weng-Keen Wong , William Hogan , Michael Wagner

Stochastic state-transition models of infectious disease transmission can be used to deduce relevant drivers of transmission when fitted to data using statistically principled methods. Fitting this individual-level data requires inference…

Methodology · Statistics 2026-02-12 James Neill , Lloyd A. C. Chapman , Chris Jewell

If model identifiability is not confirmed, inferences from infectious disease transmission models may not be reliable, so they might lead to misleading recommendations. Structural identifiability analysis characterizes whether it is…

Quantitative Methods · Quantitative Biology 2022-06-09 Emmanuelle A. Dankwa , Andrew F. Brouwer , Christl A. Donnelly

The dynamics of contact networks and epidemics of infectious diseases often occur on comparable time scales. Ignoring one of these time scales may provide an incomplete understanding of the population dynamics of the infection process. We…

Populations and Evolution · Quantitative Biology 2021-02-09 Luis E C Rocha , Naoki Masuda

This paper proposes a hierarchical Bayesian multitask learning model that is applicable to the general multi-task binary classification learning problem where the model assumes a shared sparsity structure across different tasks. We derive a…

We present an epidemiological model for vector-borne diseases that includes within-host viral load and antibody dynamics using structured transport equations. By incorporating the internal dynamics into the infected and recovered host…

Analysis of PDEs · Mathematics 2026-05-26 Paulo Amorim , Maria Soledad Aronna , Debora de Oliveira Medeiros

The rapid development of high-throughput technologies has enabled the generation of data from biological or disease processes that span multiple layers, like genomic, proteomic or metabolomic data, and further pertain to multiple sources,…

Machine Learning · Statistics 2022-01-25 Subhabrata Majumdar , George Michailidis

We propose a high dimensional Bayesian inference framework for learning heterogeneous dynamics of a COVID-19 model, with a specific application to the dynamics and severity of COVID-19 inside and outside long-term care (LTC) facilities. We…

Methodology · Statistics 2021-08-04 Peng Chen , Keyi Wu , Omar Ghattas

Understanding age-group dynamics of infectious diseases is a fundamental issue for both scientific study and policymaking. Age-structure epidemic models were developed in order to study and improve our understanding of these dynamics. By…

Populations and Evolution · Quantitative Biology 2019-11-22 Rami Yaari , Amit Huppert , Itai Dattner

Forecasting transmission of infectious diseases, especially for vector-borne diseases, poses unique challenges for researchers. Behaviors of and interactions between viruses, vectors, hosts, and the environment each play a part in…

Applications · Statistics 2020-06-02 Stephen A Lauer , Alexandria C Brown , Nicholas G Reich

Extrinsic environmental factors influence the distribution and population dynamics of many organisms, including insects that are of concern for human health and agriculture. This is particularly true for vector-borne infectious diseases,…

Quantitative Methods · Quantitative Biology 2015-03-31 Leah R. Johnson , Tal Ben-Horin , Kevin D. Lafferty , Amy McNally , Erin Mordecai , Krijn P. Paaijmans , Samraat Pawar , Sadie J. Ryan

Epidemic spreading of infectious diseases is ubiquitous and has often considerable impact on public health and economic wealth. The large variability in spatio-temporal patterns of epidemics prohibits simple interventions and demands for a…

Populations and Evolution · Quantitative Biology 2010-11-25 Christel Kamp

The contact structure between hosts has a critical influence on disease spread. However, most networkbased models used in epidemiology tend to ignore heterogeneity in the weighting of contacts. This assumption is known to be at odds with…

Populations and Evolution · Quantitative Biology 2012-09-03 Christel Kamp , Mathieu Moslonka-Lefebvre , Samuel Alizon

Within epidemiological modeling, the majority of analyses assume a single epidemic process for generating ground-truth data. However, this assumed data generation process can be unrealistic, since data sources for epidemics are often…

Artificial Intelligence · Computer Science 2021-06-22 Anna L. Trella , Peniel N. Argaw , Michelle M. Li , James A. Hay

Human mobility is a key factor in spatial disease dynamics and related phenomena. In computational models host mobility is typically modelled by diffusion in space or on metapolulation networks. Alternatively, an effective force of…

Physics and Society · Physics 2012-03-07 Vitaly Belik , Theo Geisel , Dirk Brockmann

Among the realistic ingredients to be considered in the computational modeling of infectious diseases, human mobility represents a crucial challenge both on the theoretical side and in view of the limited availability of empirical data. In…

Physics and Society · Physics 2010-02-04 Duygu Balcan , Vittoria Colizza , Bruno Goncalves , Hao Hu , Jose J. Ramasco , Alessandro Vespignani

Estimation of epidemiological and population parameters from molecular sequence data has become central to the understanding of infectious disease dynamics. Various models have been proposed to infer details of the dynamics that describe…

Populations and Evolution · Quantitative Biology 2014-12-25 Alex Popinga , Tim Vaughan , Tanja Stadler , Alexei Drummond
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