Related papers: Score-Based Matching with Target Guidance for Cryo…
We present a novel approach for extracting 3D atomic-level information from transmission electron microscopy (TEM) images affected by significant noise. The approach is based on formulating depth estimation as a semantic segmentation…
In contrast to non-medical image denoising, where enhancing image clarity is the primary goal, medical image denoising warrants preservation of crucial features without introduction of new artifacts. However, many denoising methods that…
In this paper, we introduce a novel unsupervised video denoising deep learning approach that can help to mitigate data scarcity issues and shows robustness against different noise patterns, enhancing its broad applicability. Our method…
Cryo Focused Ion-Beam Scanning Electron Microscopy (cryo FIB-SEM) enables three-dimensional and nanoscale imaging of biological specimens via a slice and view mechanism. The FIB-SEM experiments are, however, limited by a slow (typically,…
High-Resolution Transmission Electron Microscopy (HRTEM) enables atomic-scale observation of nucleation dynamics, which boosts the studies of advanced solid materials. Nonetheless, due to the millisecond-scale rapid change of nucleation, it…
Cryo-electron tomography (cryo-ET) enables structural characterization of biomolecules under near-native conditions. Existing approaches for interpreting the resulting three-dimensional volumes are computationally expensive and have…
A wide variety of image denoising methods are available now. However, the performance of a denoising algorithm often depends on individual input noisy images as well as its parameter setting. In this paper, we present a no-reference image…
Patient scans from MRI often suffer from noise, which hampers the diagnostic capability of such images. As a method to mitigate such artifact, denoising is largely studied both within the medical imaging community and beyond the community…
Cryo-EM reconstruction algorithms seek to determine a molecule's 3D density map from a series of noisy, unlabeled 2D projection images captured with an electron microscope. Although reconstruction algorithms typically model the 3D volume as…
Medical imaging modalities including magnetic resonance imaging (MRI), computed tomography (CT), and ultrasound are essential for accurate diagnosis and treatment planning in modern healthcare. However, noise contamination during image…
Fully supervised deep-learning based denoisers are currently the most performing image denoising solutions. However, they require clean reference images. When the target noise is complex, e.g. composed of an unknown mixture of primary…
Cryogenic electron tomography is a technique for imaging biological samples in 3D. A microscope collects a series of 2D projections of the sample, and the goal is to reconstruct the 3D density of the sample called the tomogram.…
Cryo-electron microscopy (cryo-EM) is a widely used technique for recovering the 3-D structure of biological molecules from a large number of experimentally generated noisy 2-D tomographic projection images of the 3-D structure, taken from…
Ultrasound images are widespread in medical diagnosis for muscle-skeletal, cardiac, and obstetrical diseases, due to the efficiency and non-invasiveness of the acquisition methodology. However, ultrasound acquisition introduces noise in the…
In this paper, we propose a unified framework of denoising score-based models in the context of graduated non-convex energy minimization. We show that for sufficiently large noise variance, the associated negative log density -- the energy…
Diffusion models are typically trained using score matching, a learning objective agnostic to the underlying noising process that guides the model. This paper argues that Markov noising processes enjoy an advantage over alternatives, as the…
Electron energy-loss spectroscopy (EELS) coupled with scanning transmission electron microscopy (STEM) is a powerful technique to determine materials composition and bonding with high spatial resolution. Noise is often a limitation…
A major challenge in single particle reconstruction from cryo-electron microscopy is to establish a reliable ab-initio three-dimensional model using two-dimensional projection images with unknown orientations. Common-lines based methods…
Evaluating canine electrocardiograms (ECGs) is challenging due to noise that can obscure clinically relevant cardiac electrical activity. Common sources of interference include respiration, muscle activity, poor lead contact, and external…
Cryo-electron tomography (Cryo-ET) is a powerful tool in structural biology for 3D visualization of cells and biological systems at resolutions sufficient to identify individual proteins in situ. The measurements are collected by tilting…