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Light-sheet fluorescence microscopy (LSFM) is used to capture volume images of biological specimens. It offers high contrast deep inside densely fluorescence labelled samples, fast acquisition speed and minimal harmful effects on the…

Image and Video Processing · Electrical Eng. & Systems 2024-04-05 Niklas Rottmayer , Claudia Redenbach , Florian Fahrbach

Lensless digital holographic microscopy (LDHM) offers very large field-of-view label-free imaging crucial, e.g., in high-throughput particle tracking and biomedical examination of cells and tissues. Compact layouts promote point-of-case and…

Optics · Physics 2023-10-24 Piotr Arcab , Mikolaj Rogalski , Maciej Trusiak

We continue our work on developing techniques for studying turbulence with spectroscopic data. We show that Doppler-broadened absorption spectral lines, in particularly, saturated absorption lines, can be used within the framework of the…

Astrophysics · Physics 2009-11-13 A. Lazarian , D. Pogosyan

Reflective ptychography is a promising lensless imaging technique with a wide field of view, offering significant potential for applications in semiconductor manufacturing and detection. However, many semiconductor materials are coated with…

Optics · Physics 2025-01-03 Yun Gao , Qijun You , Peixiang Lu , Wei Cao

In this paper, we propose a low-noise, bandwidth tunable microwave photonics filter (MPF) based on stimulated Brillouin scattering (SBS) losses. By suppressing the out-of-band signal with two broadened symmetric SBS losses, pass bandwidth…

Applied Physics · Physics 2017-09-22 Cheng Feng , Stefan Preussler , Thomas Schneider

Stimulated Raman scattering (SRS) microscopy is a powerful label-free imaging technique that probes the vibrational response of chemicals with high specificity and sensitivity. High-power, quantum-enhanced SRS microscopes have been recently…

Narrow linewidth stabilized lasers are central to precision applications that operate across the visible to short-wave infrared wavelengths, including optical clocks, quantum sensing and computing, ultra-low noise microwave generation, and…

We describe the apparatus of a fluorescence optical microscope with both single-photon and two-photon non-diffracting light sheets excitation for large volume imaging. With special design to accommodate two different wavelength ranges…

Instrumentation and Detectors · Physics 2018-04-04 Sze Cheung Lau , Hoi Chun Chiu , Luwei Zhao , Teng Zhao , M. M. T. Loy , Shengwang Du

Brillouin Microscopy is a novel label-free optical technique that enables the measurement of a material's mechanical properties at the sub-micron scale in a non-invasive and non-contact way; in the last few years, its applications in the…

This paper presents a regularized sampling method for multiband signals, that makes it possible to approach the Landau limit, while keeping the sensitivity to noise at a low level. The method is based on band-limited windowing, followed by…

Information Theory · Computer Science 2015-05-18 J. Selva

A single-pixel digital holography system with phase-encoded illumination using a digital micromirror device (DMD) as a spatial light modulator (SLM) is presented. The enhanced switching rate of DMDs, far exceeding the stringent frame-rate…

Background: Photoacoustic Microscopy (PAM) integrates optical and acoustic imaging, offering enhanced penetration depth for detecting optical-absorbing components in tissues. Nonetheless, challenges arise in scanning large areas with high…

Medical Physics · Physics 2023-12-15 Irem Loc , Mehmet Burcin Unlu

Brillouin spectroscopy is commonly used to study the acoustic properties of materials. Here we explored its feasibility in studying the photoinduced isomerization of azobenzene. The isomerization of azobenzene changes the solution elastic…

Brillouin imaging suffers from intrinsically low signal-to-noise ratios (SNR). Such low SNRs can render common data analysis protocols unreliable, especially for SNRs below $\sim10$. In this work we exploit two denoising algorithms, namely…

Signal Processing · Electrical Eng. & Systems 2020-01-24 YuChen Xiang , Matthew R. Foreman , Peter Török

Exposure to laser light alters cell culture examination via optical microscopic imaging techniques, also based on label-free coherent digital holography. To mitigate this detrimental feature, researchers tend to use a broader spectrum and…

We explore the multiphase structure of the circumgalactic medium (CGM) probed by synthetic spectra through a cosmological zoom-in galaxy formation simulation. We employ a Bayesian method for modelling a combination of absorption lines to…

Astrophysics of Galaxies · Physics 2018-07-11 Cameron Liang , Andrey Kravtsov , Oscar Agertz

Lensless imaging is an elegant approach to high-resolution microscopy, which is rapidly gaining popularity in applications where imaging optics are problematic. However, current lensless imaging methods require objects to be placed within a…

Sonography techniques use multiple transducer elements for tissue visualization. Signals detected at each element are sampled prior to digital beamforming. The sampling rates required to perform high resolution digital beamforming are…

Information Theory · Computer Science 2013-07-25 Tanya Chernyakova , Yonina C. Eldar

High-speed multiplex imaging of fluorescent probes is limited by a combination of spectral resolution, sensitivity, high cost and low light throughput of detectors, and filters. In this work, we present a hyperspectral detection system…

Multi-beam ptychography (MBP) offers a scalable solution to improve the throughput of state-of-the-art ptychography by increasing the number of coherent beams that illuminate the sample simultaneously. However, increasing the number of…

Optics · Physics 2025-10-29 Runqing Yang , Pablo Villanueva-Perez , Maik Kahnt
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