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Objective: To allow efficient learning using the Recurrent Inference Machine (RIM) for image reconstruction whereas not being strictly dependent on the training data distribution so that unseen modalities and pathologies are still…

Image and Video Processing · Electrical Eng. & Systems 2020-12-15 Dimitrios Karkalousos , Kai Lønning , Hanneke E. Hulst , Serge O. Dumoulin , Jan-Jakob Sonke , Frans M. Vos , Matthan W. A. Caan

Foundation models refer to architectures trained on vast datasets using autoregressive pre-training from natural language processing to capture intricate patterns and motifs. They were originally developed to transfer such learned knowledge…

Machine Learning · Computer Science 2025-10-28 Nicholas I-Hsien Kuo , Blanca Gallego , Louisa Jorm

Modern large language models (LLMs) are often evaluated and deployed under a one-shot, greedy inference protocol, especially in professional settings that require deterministic behavior. This regime can systematically under-estimate a fixed…

Artificial Intelligence · Computer Science 2026-02-13 Xinhai Sun

Objective: Endophenotypes such as brain age and fluid intelligence are important biomarkers of disease status. However, brain imaging studies to identify these biomarkers often encounter limited numbers of subjects and high dimensional…

Quantitative Methods · Quantitative Biology 2022-12-29 Anton Orlichenko , Gang Qu , Gemeng Zhang , Binish Patel , Tony W. Wilson , Julia M. Stephen , Vince D. Calhoun , Yu-Ping Wang

We propose a novel framework for retinal feature point alignment, designed for learning cross-modality features to enhance matching and registration across multi-modality retinal images. Our model draws on the success of previous…

Image and Video Processing · Electrical Eng. & Systems 2024-07-29 Jiacheng Wang , Hao Li , Dewei Hu , Rui Xu , Xing Yao , Yuankai K. Tao , Ipek Oguz

Deterministic inference is increasingly critical for large language model (LLM) applications such as LLM-as-a-judge evaluation, multi-agent systems, and Reinforcement Learning (RL). However, existing LLM serving frameworks exhibit…

Machine Learning · Computer Science 2025-11-25 Ziyang Zhang , Xinheng Ding , Jiayi Yuan , Rixin Liu , Huizi Mao , Jiarong Xing , Zirui Liu

State-of-the-art neural networks are vulnerable to adversarial examples; they can easily misclassify inputs that are imperceptibly different than their training and test data. In this work, we establish that the use of cross-entropy loss…

Machine Learning · Computer Science 2019-01-25 Kamil Nar , Orhan Ocal , S. Shankar Sastry , Kannan Ramchandran

Diabetic retinopathy (DR) is a leading cause of blindness worldwide, necessitating early detection to prevent vision loss. Current automated DR detection systems often struggle with poor-quality images, lack interpretability, and…

Image and Video Processing · Electrical Eng. & Systems 2025-09-03 Idowu Paul Okuwobi , Jingyuan Liu , Jifeng Wan , Jiaojiao Jiang

Spatiotemporal predictive learning aims to generate future frames by learning from historical frames. In this paper, we investigate existing methods and present a general framework of spatiotemporal predictive learning, in which the spatial…

Computer Vision and Pattern Recognition · Computer Science 2023-04-13 Cheng Tan , Zhangyang Gao , Lirong Wu , Yongjie Xu , Jun Xia , Siyuan Li , Stan Z. Li

Human-in-the-loop validation is essential in safety-critical clinical AI, yet the transition between initial model inference and expert correction is rarely analyzed as a structured signal. We introduce a diagnostic alignment framework in…

Artificial Intelligence · Computer Science 2026-02-27 Dimitrios P. Panagoulias , Evangelia-Aikaterini Tsichrintzi , Georgios Savvidis , Evridiki Tsoureli-Nikita

This paper presents a comparative analysis of deep learning strategies for detecting hypertensive retinopathy from fundus images, a central task in the HRDC challenge~\cite{qian2025hrdc}. We investigate three distinct approaches: a custom…

Computer Vision and Pattern Recognition · Computer Science 2025-06-17 Yanqiao Zhu

Encouraged by the success of deep learning in a variety of domains, we investigate the suitability and effectiveness of Recurrent Neural Networks (RNNs) in a domain where deep learning has not yet been used; namely detecting confusion from…

Computer Vision and Pattern Recognition · Computer Science 2019-06-27 Shane D. Sims , Vanessa Putnam , Cristina Conati

Deep energy-based models are powerful, but pose challenges for learning and inference (Belanger and McCallum, 2016). Tu and Gimpel (2018) developed an efficient framework for energy-based models by training "inference networks" to…

Computation and Language · Computer Science 2020-10-13 Lifu Tu , Richard Yuanzhe Pang , Kevin Gimpel

Fr\'echet Inception Distance (FID), computed with an ImageNet pretrained Inception-v3 network, is widely used as a state-of-the-art evaluation metric for generative models. It assumes that feature vectors from Inception-v3 follow a…

Computer Vision and Pattern Recognition · Computer Science 2026-02-23 Yuli Wu , Fucheng Liu , Rüveyda Yilmaz , Henning Konermann , Peter Walter , Johannes Stegmaier

Deep learning models have gained increasing adoption in medical image analysis. However, these models often produce overconfident predictions, which can compromise clinical accuracy and reliability. Bridging the gap between high-performance…

Image and Video Processing · Electrical Eng. & Systems 2026-03-24 Jutika Borah , Hidam Kumarjit Singh

Current Reinforcement Fine-tuning (RFT) paradigms for Large Language Models (LLMs) suffer from sample inefficiency due to the redundant exposure of identical queries under uniform data sampling. While previous work has explored curriculum…

Machine Learning · Computer Science 2025-09-30 Qinsi Wang , Jinghan Ke , Hancheng Ye , Yueqian Lin , Yuzhe Fu , Jianyi Zhang , Kurt Keutzer , Chenfeng Xu , Yiran Chen

Supervised Fine-Tuning (SFT) is the standard paradigm for domain adaptation, yet it frequently incurs the cost of catastrophic forgetting. In sharp contrast, on-policy Reinforcement Learning (RL) effectively preserves general capabilities.…

Machine Learning · Computer Science 2026-01-06 Muxi Diao , Lele Yang , Wuxuan Gong , Yutong Zhang , Zhonghao Yan , Yufei Han , Kongming Liang , Weiran Xu , Zhanyu Ma

Glaucoma is one of the major eye diseases that leads to progressive optic nerve fiber damage and irreversible blindness, afflicting millions of individuals. Glaucoma forecast is a good solution to early screening and intervention of…

Computer Vision and Pattern Recognition · Computer Science 2024-02-22 Xikai Yang , Jian Wu , Xi Wang , Yuchen Yuan , Ning Li Wang , Pheng-Ann Heng

Modeling large-scale time series has gained significant attention in recent years. However, its direct application in finance remains challenging due to substantial differences in data characteristics across domains. Specifically, financial…

Artificial Intelligence · Computer Science 2025-10-22 Yuanjian Xu , Anxian Liu , Jianing Hao , Zhenzhuo Li , Shichang Meng , Guang Zhang

Recent progress in generative modeling has enabled high-quality visual synthesis with diffusion-based frameworks, supporting controllable sampling and large-scale training. Inference-time guidance methods such as classifier-free and…

Computer Vision and Pattern Recognition · Computer Science 2026-02-02 Wenqiang Zu , Shenghao Xie , Bo Lei , Lei Ma