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Contextual word embedding models, such as BioBERT and Bio_ClinicalBERT, have achieved state-of-the-art results in biomedical natural language processing tasks by focusing their pre-training process on domain-specific corpora. However, such…

Computation and Language · Computer Science 2021-06-04 George Michalopoulos , Yuanxin Wang , Hussam Kaka , Helen Chen , Alexander Wong

Recent advances in natural language processing (NLP) owe their success to pre-training language models on large amounts of unstructured data. Still, there is an increasing effort to combine the unstructured nature of LMs with structured…

Computation and Language · Computer Science 2023-12-22 Juraj Vladika , Alexander Fichtl , Florian Matthes

Pre-trained transformer language models (LMs) have in recent years become the dominant paradigm in applied NLP. These models have achieved state-of-the-art performance on tasks such as information extraction, question answering, sentiment…

Computation and Language · Computer Science 2025-04-14 Aidan Mannion , Thierry Chevalier , Didier Schwab , Lorraine Geouriot

Large language models (LLMs) are rapidly transforming various domains, including biomedicine and healthcare, and demonstrate remarkable potential from scientific research to new drug discovery. Graph-based retrieval-augmented generation…

Quantitative Methods · Quantitative Biology 2025-11-14 Guofeng Meng , Li Shen , Qiuyan Zhong , Wei Wang , Haizhou Zhang , Xiaozhen Wang

In Natural Language Processing (NLP), Machine Reading Comprehension (MRC) is the task of answering a question based on a given context. To handle questions in the medical domain, modern language models such as BioBERT, SciBERT and even…

Computation and Language · Computer Science 2024-12-16 Saptarshi Sengupta , Connor Heaton , Suhan Cui , Soumalya Sarkar , Prasenjit Mitra

Pretrained language models have shown success in many natural language processing tasks. Many works explore incorporating knowledge into language models. In the biomedical domain, experts have taken decades of effort on building large-scale…

Computation and Language · Computer Science 2021-04-22 Zheng Yuan , Yijia Liu , Chuanqi Tan , Songfang Huang , Fei Huang

Pretraining large neural language models, such as BERT, has led to impressive gains on many natural language processing (NLP) tasks. However, most pretraining efforts focus on general domain corpora, such as newswire and Web. A prevailing…

Computation and Language · Computer Science 2021-09-20 Yu Gu , Robert Tinn , Hao Cheng , Michael Lucas , Naoto Usuyama , Xiaodong Liu , Tristan Naumann , Jianfeng Gao , Hoifung Poon

Large language models (LLMs) are transforming the way information is retrieved with vast amounts of knowledge being summarized and presented via natural language conversations. Yet, LLMs are prone to highlight the most frequently seen…

Computation and Language · Computer Science 2024-02-20 Julien Delile , Srayanta Mukherjee , Anton Van Pamel , Leonid Zhukov

In this study, we investigate the potential of Large Language Models to complement biomedical knowledge graphs in the training of semantic models for the biomedical and clinical domains. Drawing on the wealth of the UMLS knowledge graph and…

Computation and Language · Computer Science 2023-11-28 François Remy , Kris Demuynck , Thomas Demeester

Large Language Models (LLMs) have achieved exceptional capabilities in open generation across various domains, yet they encounter difficulties with tasks that require intensive knowledge. To address these challenges, methods for integrating…

Computation and Language · Computer Science 2024-12-17 Fali Wang , Runxue Bao , Suhang Wang , Wenchao Yu , Yanchi Liu , Wei Cheng , Haifeng Chen

In recent years, there has been substantial progress in using pretrained Language Models (LMs) on a range of tasks aimed at improving the understanding of biomedical texts. Nonetheless, existing biomedical LLMs show limited comprehension of…

Computation and Language · Computer Science 2025-09-10 Andrey Sakhovskiy , Elena Tutubalina

Recently, biomedical version of embeddings obtained from language models such as BioELMo have shown state-of-the-art results for the textual inference task in the medical domain. In this paper, we explore how to incorporate structured…

Computation and Language · Computer Science 2021-09-07 Soumya Sharma , Bishal Santra , Abhik Jana , T. Y. S. S. Santosh , Niloy Ganguly , Pawan Goyal

Large Language Models (LLMs) demonstrate remarkable versatility in various NLP tasks but encounter distinct challenges in biomedical due to the complexities of language and data scarcity. This paper investigates LLMs application in the…

Computation and Language · Computer Science 2024-07-12 Masoud Monajatipoor , Jiaxin Yang , Joel Stremmel , Melika Emami , Fazlolah Mohaghegh , Mozhdeh Rouhsedaghat , Kai-Wei Chang

Knowledge Graphs (KGs) are essential for the functionality of GraphRAGs, a form of Retrieval-Augmented Generative Systems (RAGs) that excel in tasks requiring structured reasoning and semantic understanding. However, creating KGs for…

Computation and Language · Computer Science 2024-12-11 Ahan Bhatt , Nandan Vaghela , Kush Dudhia

Language model (LM) pretraining can learn various knowledge from text corpora, helping downstream tasks. However, existing methods such as BERT model a single document, and do not capture dependencies or knowledge that span across…

Computation and Language · Computer Science 2022-03-31 Michihiro Yasunaga , Jure Leskovec , Percy Liang

Contextualized word embeddings derived from pre-trained language models (LMs) show significant improvements on downstream NLP tasks. Pre-training on domain-specific corpora, such as biomedical articles, further improves their performance.…

Computation and Language · Computer Science 2019-04-05 Qiao Jin , Bhuwan Dhingra , William W. Cohen , Xinghua Lu

Off-the-shelf biomedical embeddings obtained from the recently released various pre-trained language models (such as BERT, XLNET) have demonstrated state-of-the-art results (in terms of accuracy) for the various natural language…

Computation and Language · Computer Science 2020-12-22 Ishani Mondal

Large Language Models (LLMs) are being adopted at an unprecedented rate, yet still face challenges in knowledge-intensive domains like biomedicine. Solutions such as pre-training and domain-specific fine-tuning add substantial computational…

The overwhelming amount of biomedical scientific texts calls for the development of effective language models able to tackle a wide range of biomedical natural language processing (NLP) tasks. The most recent dominant approaches are…

Computation and Language · Computer Science 2021-04-21 Giacomo Miolo , Giulio Mantoan , Carlotta Orsenigo

Pretrained language models have served as important backbones for natural language processing. Recently, in-domain pretraining has been shown to benefit various domain-specific downstream tasks. In the biomedical domain, natural language…

Computation and Language · Computer Science 2022-04-25 Hongyi Yuan , Zheng Yuan , Ruyi Gan , Jiaxing Zhang , Yutao Xie , Sheng Yu
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