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Related papers: Injecting Structured Biomedical Knowledge into Lan…

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Drug repurposing plays a critical role in accelerating treatment discovery, especially for complex and rare diseases. Biomedical knowledge graphs (KGs), which encode rich clinical associations, have been widely adopted to support this task.…

Computation and Language · Computer Science 2025-10-15 Chengrui Xiang , Tengfei Ma , Xiangzheng Fu , Yiping Liu , Bosheng Song , Xiangxiang Zeng

Pre-trained language models have attracted increasing attention in the biomedical domain, inspired by their great success in the general natural language domain. Among the two main branches of pre-trained language models in the general…

Computation and Language · Computer Science 2023-04-04 Renqian Luo , Liai Sun , Yingce Xia , Tao Qin , Sheng Zhang , Hoifung Poon , Tie-Yan Liu

Objective: Biomedical Knowledge Graphs play a pivotal role in various biomedical research domains. Concurrently, term clustering emerges as a crucial step in constructing these knowledge graphs, aiming to identify synonymous terms. Due to a…

Computation and Language · Computer Science 2023-12-14 Huaiyuan Ying , Zhengyun Zhao , Yang Zhao , Sihang Zeng , Sheng Yu

The way we analyse clinical texts has undergone major changes over the last years. The introduction of language models such as BERT led to adaptations for the (bio)medical domain like PubMedBERT and ClinicalBERT. These models rely on large…

Computation and Language · Computer Science 2023-09-15 Tom van Sonsbeek , Xiantong Zhen , Marcel Worring

Pre-training large-scale neural language models on raw texts has made a significant contribution to improving transfer learning in natural language processing (NLP). With the introduction of transformer-based language models, such as…

Computation and Language · Computer Science 2024-05-08 Shoya Wada , Toshihiro Takeda , Shiro Manabe , Shozo Konishi , Jun Kamohara , Yasushi Matsumura

In this work, we aim at equipping pre-trained language models with structured knowledge. We present two self-supervised tasks learning over raw text with the guidance from knowledge graphs. Building upon entity-level masked language models,…

Computation and Language · Computer Science 2020-04-30 Tao Shen , Yi Mao , Pengcheng He , Guodong Long , Adam Trischler , Weizhu Chen

Large language models (LLMs) encode knowledge in parametric weights, making it costly to update or extend without retraining. Retrieval-augmented generation (RAG) mitigates this limitation by appending retrieved text to the input, but…

Computation and Language · Computer Science 2026-04-24 Bin Ju , Shenfeng Weng , Danying Zhou , Rongkai Xu , Kunkai Su

We present a refined approach to biomedical question-answering (QA) services by integrating large language models (LLMs) with Multi-BERT configurations. By enhancing the ability to process and prioritize vast amounts of complex biomedical…

Computation and Language · Computer Science 2024-10-18 Cheng Qian , Xianglong Shi , Shanshan Yao , Yichen Liu , Fengming Zhou , Zishu Zhang , Junaid Akram , Ali Braytee , Ali Anaissi

The question-answering system for Life science research, which is characterized by the rapid pace of discovery, evolving insights, and complex interactions among knowledge entities, presents unique challenges in maintaining a comprehensive…

Computation and Language · Computer Science 2024-08-15 Chengrui Wang , Qingqing Long , Meng Xiao , Xunxin Cai , Chengjun Wu , Zhen Meng , Xuezhi Wang , Yuanchun Zhou

Retrieval-Augmented Generation (RAG) has emerged as a prominent method for incorporating domain knowledge into Large Language Models (LLMs). While RAG enhances response relevance by incorporating retrieved domain knowledge in the context,…

Computation and Language · Computer Science 2025-03-28 Kushagra Bhushan , Yatin Nandwani , Dinesh Khandelwal , Sonam Gupta , Gaurav Pandey , Dinesh Raghu , Sachindra Joshi

Knowledge graphs are powerful tools for representing and organising complex biomedical data. Several knowledge graph embedding algorithms have been proposed to learn from and complete knowledge graphs. However, a recent study demonstrates…

Question answering is a natural language understanding task that involves reasoning over both explicit context, and unstated relevant domain knowledge. Despite the high cost of training, large language models (LLMs) -- the backbone of most…

Computation and Language · Computer Science 2025-04-24 Laura Cabello , Carmen Martin-Turrero , Uchenna Akujuobi , Anders Søgaard , Carlos Bobed

Large language models (LLMs) often require vast amounts of text to effectively acquire new knowledge. While continuing pre-training on large corpora or employing retrieval-augmented generation (RAG) has proven successful, updating an LLM…

Computation and Language · Computer Science 2025-08-11 Hugo Abonizio , Thales Almeida , Roberto Lotufo , Rodrigo Nogueira

With the growing amount of text in health data, there have been rapid advances in large pre-trained models that can be applied to a wide variety of biomedical tasks with minimal task-specific modifications. Emphasizing the cost of these…

Large language models (LLMs) are increasingly recognized as valuable tools across the medical environment, supporting clinical, research, and administrative workflows. However, strict privacy and network security regulations in hospital…

Computation and Language · Computer Science 2026-01-09 Seokhwan Ko , Donghyeon Lee , Jaewoo Chun , Hyungsoo Han , Junghwan Cho

Linking biomedical entities is an essential aspect in biomedical natural language processing tasks, such as text mining and question answering. However, a difficulty of linking the biomedical entities using current large language models…

Computation and Language · Computer Science 2023-08-29 Xi Yan , Cedric Möller , Ricardo Usbeck

The introduction of Large Language Models (LLMs), and the vast volume of publicly available medical data, amplified the application of NLP to the medical domain. However, LLMs are pretrained on data that are not explicitly relevant to the…

Computation and Language · Computer Science 2023-12-12 Chris Solomou

Most biomedical pretrained language models are monolingual and cannot handle the growing cross-lingual requirements. The scarcity of non-English domain corpora, not to mention parallel data, poses a significant hurdle in training…

Computation and Language · Computer Science 2023-11-21 Lei Geng , Xu Yan , Ziqiang Cao , Juntao Li , Wenjie Li , Sujian Li , Xinjie Zhou , Yang Yang , Jun Zhang

Large language models (LLMs) have recently become the leading source of answers for users' questions online. Despite their ability to offer eloquent answers, their accuracy and reliability can pose a significant challenge. This is…

Computation and Language · Computer Science 2024-07-09 Bojana Bašaragin , Adela Ljajić , Darija Medvecki , Lorenzo Cassano , Miloš Košprdić , Nikola Milošević

This paper introduces a pioneering methodology, termed StructTuning, to efficiently transform foundation Large Language Models (LLMs) into domain specialists. It significantly reduces the training corpus needs to a mere 5% while achieving…

Computation and Language · Computer Science 2025-02-18 Kai Liu , Ze Chen , Zhihang Fu , Wei Zhang , Rongxin Jiang , Fan Zhou , Yaowu Chen , Yue Wu , Jieping Ye