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Diagnosing knee joint osteoarthritis (KOA), a major cause of disability worldwide, is challenging due to subtle radiographic indicators and the varied progression of the disease. Using deep learning for KOA diagnosis requires broad,…

Image and Video Processing · Electrical Eng. & Systems 2024-09-26 Fabi Prezja , Leevi Annala , Sampsa Kiiskinen , Timo Ojala

Introduction: Bone health disorders like osteoarthritis and osteoporosis pose major global health challenges, often leading to delayed diagnoses due to limited diagnostic tools. This study presents an AI-powered system that analyzes knee…

Musculoskeletal disorders represent a significant global health burden and are a leading cause of disability worldwide. While MRI is essential for accurate diagnosis, its interpretation remains exceptionally challenging. Radiologists must…

Computer Vision and Pattern Recognition · Computer Science 2026-02-25 Tian Lan , Lei Xu , Zimu Yuan , Shanggui Liu , Jiajun Liu , Jiaxin Liu , Weilai Xiang , Hongyu Yang , Dong Jiang , Jianxin Yin , Dingyu Wang

Existing artificial intelligence (AI) models for diagnosing knee osteoarthritis (OA) have faced criticism for their lack of transparency and interpretability, despite achieving medical-expert-like performance. This opacity makes them…

Machine Learning · Computer Science 2023-08-21 Yun Xin Teoh , Alice Othmani , Siew Li Goh , Juliana Usman , Khin Wee Lai

Alzheimer's disease (AD) diagnosis requires integrating neuroimaging with heterogeneous clinical evidence and reasoning under established criteria, yet most multimodal models remain opaque and weakly guideline-aligned. We present…

Computer Vision and Pattern Recognition · Computer Science 2026-03-26 Qiuhui Chen , Yushan Deng , Xuancheng Yao , Yi Hong

Knee osteoarthritis (KOA) is a disease that impairs knee function and causes pain. A radiologist reviews knee X-ray images and grades the severity level of the impairments according to the Kellgren and Lawrence grading scheme; a five-point…

Image and Video Processing · Electrical Eng. & Systems 2019-08-26 Jaynal Abedin , Joseph Antony , Kevin McGuinness , Kieran Moran , Noel E O'Connor , Dietrich Rebholz-Schuhmann , John Newell

Knee osteoporosis weakens the bone tissue in the knee joint, increasing fracture risk. Early detection through X-ray images enables timely intervention and improved patient outcomes. While some researchers have focused on diagnosing knee…

Image and Video Processing · Electrical Eng. & Systems 2024-12-13 Ayesha Siddiqua , Rakibul Hasan , Anichur Rahman , Abu Saleh Musa Miah

Knee osteoarthritis is a degenerative joint disease that induces chronic pain and disability. Bone morphological analysis is a promising tool to understand the mechanical aspect of this disorder. This study proposes a 2D bone morphological…

Image and Video Processing · Electrical Eng. & Systems 2024-03-14 Yun Xin Teoh , Alice Othmani , Siew Li Goh , Juliana Usman , Khin Wee Lai

Conventional inclusion criteria used in osteoarthritis clinical trials are not very effective in selecting patients who would benefit from a therapy being tested. Typically majority of selected patients show no or limited disease…

The aim of this study was to investigate the influence of MRI and patient data on the prediction of knee osteoarthritis (OA) incidence using different deep learning architectures. Knee OA incidence within 24 months was predicted using the…

Medical Physics · Physics 2022-09-05 Anastasis Alexopoulos , Jukka Hirvasniemi , Nazli Tümer

Osteoarthritis (OA) is the most common musculoskeletal disease, with knee OA (KOA) being one of the leading causes of disability and a significant economic burden. Predicting KOA progression is crucial for improving patient outcomes,…

Machine Learning · Computer Science 2025-04-09 Khanh Nguyen , Huy Hoang Nguyen , Egor Panfilov , Aleksei Tiulpin

Multimodal neuroimaging provides complementary structural and functional insights into both human brain organization and disease-related dynamics. Recent studies demonstrate enhanced diagnostic sensitivity for Alzheimer's disease (AD)…

Multimedia · Computer Science 2025-04-24 Yuxiang Wei , Yanteng Zhang , Xi Xiao , Tianyang Wang , Xiao Wang , Vince D. Calhoun

This research paper explores the classification of knee osteoarthritis (OA) severity levels using advanced computer vision models and augmentation techniques. The study investigates the effectiveness of data preprocessing, including…

Knee osteoarthritis (OA) is one of the most common musculoskeletal disorders and requires early-stage diagnosis. Nowadays, the deep convolutional neural networks have achieved greatly in the computer-aided diagnosis field. However, the…

Image and Video Processing · Electrical Eng. & Systems 2020-10-13 Jiayu Huo , Liping Si , Xi Ouyang , Kai Xuan , Weiwu Yao , Zhong Xue , Qian Wang , Dinggang Shen , Lichi Zhang

A fully automated knee MRI segmentation method to study osteoarthritis (OA) was developed using a novel hierarchical set of random forests (RF) classifiers to learn the appearance of cartilage regions and their boundaries. A neighborhood…

Computer Vision and Pattern Recognition · Computer Science 2019-03-12 Satyananda Kashyap , Honghai Zhang , Karan Rao , Milan Sonka

The diagnostic accuracy and subjectivity of existing Knee Osteoarthritis (OA) ordinal grading systems has been a subject of on-going debate and concern. Existing automated solutions are trained to emulate these imperfect systems, whilst…

Machine Learning · Computer Science 2025-05-30 Niamh Belton , Aonghus Lawlor , Kathleen M. Curran

Knee osteoarthritis (OA) is a common degenerate joint disorder that affects a large population of elderly people worldwide. Accurate radiographic assessment of knee OA severity plays a critical role in chronic patient management. Current…

Image and Video Processing · Electrical Eng. & Systems 2021-12-20 Kang Zheng , Yirui Wang , Chen-I Hsieh , Le Lu , Jing Xiao , Chang-Fu Kuo , Shun Miao

Knee osteoarthritis (OA) is the most common musculoskeletal disorder. OA diagnosis is currently conducted by assessing symptoms and evaluating plain radiographs, but this process suffers from subjectivity. In this study, we present a new…

Computer Vision and Pattern Recognition · Computer Science 2017-10-31 Aleksei Tiulpin , Jérôme Thevenot , Esa Rahtu , Petri Lehenkari , Simo Saarakkala

Early multiple sclerosis (MS) disability progression prediction is challenging due to disease heterogeneity. This work predicts 48- and 72-week disability using sparse baseline clinical data and 12 weeks of daily digital Floodlight data…

Machine Learning · Computer Science 2025-06-19 Maxime Usdin , Lito Kriara , Licinio Craveiro

Knee-Joint Osteoarthritis (KOA) is a prevalent cause of global disability and is inherently complex to diagnose due to its subtle radiographic markers and individualized progression. One promising classification avenue involves applying…

Image and Video Processing · Electrical Eng. & Systems 2023-11-13 Fabi Prezja , Leevi Annala , Sampsa Kiiskinen , Suvi Lahtinen , Timo Ojala