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In medical applications, deep learning methods are built to automate diagnostic tasks. However, a clinically relevant question that practitioners usually face, is how to predict the future trajectory of a disease (prognosis). Current…

Machine Learning · Computer Science 2021-12-08 Huy Hoang Nguyen , Simo Saarakkala , Matthew B. Blaschko , Aleksei Tiulpin

Knee Osteoarthritis (KOA) is a highly prevalent chronic musculoskeletal condition with no currently available treatment. The manifestation of KOA is heterogeneous and prediction of its progression is challenging. Current literature suggests…

Image and Video Processing · Electrical Eng. & Systems 2023-07-04 Egor Panfilov , Simo Saarakkala , Miika T. Nieminen , Aleksei Tiulpin

Diagnosing knee osteoarthritis (OA) early is crucial for managing symptoms and preventing further joint damage, ultimately improving patient outcomes and quality of life. In this paper, a bioimpedance-based diagnostic tool that combines…

Signal Processing · Electrical Eng. & Systems 2025-05-06 Jamal Al-Nabulsi , Mohammad Al-Sayed Ahmad , Baraa Hasaneiah , Fayhaa AlZoubi

Distal myopathy represents a genetically heterogeneous group of skeletal muscle disorders with broad clinical manifestations, posing diagnostic challenges in radiology. To address this, we propose a novel multimodal attention-aware fusion…

Medical imaging plays a crucial role in assessing knee osteoarthritis (OA) risk by enabling early detection and disease monitoring. Recent machine learning methods have improved risk estimation (i.e., predicting the likelihood of disease…

Computer Vision and Pattern Recognition · Computer Science 2025-06-18 David Butler , Adrian Hilton , Gustavo Carneiro

Accurate prediction of knee osteoarthritis (KOA) progression from structural MRI has a potential to enhance disease understanding and support clinical trials. Prior art focused on manually designed imaging biomarkers, which may not fully…

Image and Video Processing · Electrical Eng. & Systems 2024-08-07 Egor Panfilov , Simo Saarakkala , Miika T. Nieminen , Aleksei Tiulpin

Knee Osteoarthritis (OA) is a destructive joint disease identified by joint stiffness, pain, and functional disability concerning millions of lives across the globe. It is generally assessed by evaluating physical symptoms, medical history,…

Image and Video Processing · Electrical Eng. & Systems 2024-10-28 Rohit Kumar Jain , Prasen Kumar Sharma , Sibaji Gaj , Arijit Sur , Palash Ghosh

Knee osteoarthritis (OA) is the most common musculoskeletal disease without a cure, and current treatment options are limited to symptomatic relief. Prediction of OA progression is a very challenging and timely issue, and it could, if…

Computer Vision and Pattern Recognition · Computer Science 2019-05-07 Aleksei Tiulpin , Stefan Klein , Sita M. A. Bierma-Zeinstra , Jérôme Thevenot , Esa Rahtu , Joyce van Meurs , Edwin H. G. Oei , Simo Saarakkala

Knee Osteoarthritis (KOA) is a prevalent musculoskeletal disorder that severely impacts mobility and quality of life, particularly among older adults. Its diagnosis often relies on subjective assessments using the Kellgren-Lawrence (KL)…

Image and Video Processing · Electrical Eng. & Systems 2025-01-17 Zhe Wang , Aladine Chetouani , Yung Hsin Chen , Yuhua Ru , Fang Chen , Mohamed Jarraya , Fabian Bauer , Liping Zhang , Didier Hans , Rachid Jennane

Osteoporosis is a common condition that increases fracture risk, especially in older adults. Early diagnosis is vital for preventing fractures, reducing treatment costs, and preserving mobility. However, healthcare providers face challenges…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Mehdi Hosseini Chagahi , Saeed Mohammadi Dashtaki , Niloufar Delfan , Nadia Mohammadi , Farshid Rostami Pouria , Behzad Moshiri , Md. Jalil Piran , Oliver Faust

Knee osteoarthritis (KOA) is among the musculoskeletal disorders that considerably restrict joint mobility, cause severe chronic pain and impact negatively on quality life. It is one of the persistent health issues worldwide. Generally,…

Artificial Intelligence · Computer Science 2026-05-08 Dayam Nadeem , Neha , Safdar Mustafa , Adnan Alvi , Mohd Hussain

Knee osteoarthritis (KOA) grading based on radiographic images is a critical yet challenging task due to subtle inter-grade differences, annotation uncertainty, and the inherently ordinal nature of disease progression. Conventional deep…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Xiaoyang Li , Runni Zhou

Knee osteoarthritis (KOA), a common form of arthritis that causes physical disability, has become increasingly prevalent in society. Employing computer-aided techniques to automatically assess the severity and progression of KOA can greatly…

Image and Video Processing · Electrical Eng. & Systems 2024-08-01 Wenhua Wu , Kun Hu , Wenxi Yue , Wei Li , Milena Simic , Changyang Li , Wei Xiang , Zhiyong Wang

In medical image analysis, automated segmentation of multi-component anatomical structures, which often have a spectrum of potential anomalies and pathologies, is a challenging task. In this work, we develop a multi-step approach using…

Image and Video Processing · Electrical Eng. & Systems 2022-12-02 Boyeong Woo , Craig Engstrom , William Baresic , Jurgen Fripp , Stuart Crozier , Shekhar S. Chandra

Knee osteoarthritis (KOA) diagnosis from radiographs remains challenging due to the subtle morphological details that standard deep learning models struggle to capture effectively. We propose a novel multimodal framework that combines…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Marouane Tliba , Mohamed Amine Kerkouri , Yassine Nasser , Nour Aburaed , Aladine Chetouani , Ulas Bagci , Rachid Jennane

Musculoskeletal disorders represent a leading cause of global disability, creating an urgent demand for precise interpretation of medical imaging. Current artificial intelligence (AI) approaches in orthopedics predominantly rely on…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Kang Yu , Dingyu Wang , Zimu Yuan , Nan Zhou , Jiajun Liu , Jiaxin Liu , Shanggui Liu , Yaoyan Zheng , Huishu Yuan , Di Huang , Dong Jiang

Deep neural networks are often applied to medical images to automate the problem of medical diagnosis. However, a more clinically relevant question that practitioners usually face is how to predict the future trajectory of a disease.…

Image and Video Processing · Electrical Eng. & Systems 2023-09-20 Huy Hoang Nguyen , Matthew B. Blaschko , Simo Saarakkala , Aleksei Tiulpin

Automated grading of Knee Osteoarthritis (KOA) from radiographs is challenged by significant inter-observer variability and the limited robustness of deep learning models, particularly near critical decision boundaries. To address these…

Image and Video Processing · Electrical Eng. & Systems 2025-06-23 Zhe Wang , Yuhua Ru , Aladine Chetouani , Tina Shiang , Fang Chen , Fabian Bauer , Liping Zhang , Didier Hans , Rachid Jennane , William Ewing Palmer , Mohamed Jarraya , Yung Hsin Chen

Knee osteoarthritis (KOA) affects more than 600 million individuals globally and is associated with significant pain, functional impairment, and disability. While personalized multidisciplinary interventions have the potential to slow…

Artificial Intelligence · Computer Science 2025-11-26 Weizhi Liu , Xi Chen , Zekun Jiang , Liang Zhao , Kunyuan Jiang , Ruisi Tang , Li Wang , Mingke You , Hanyu Zhou , Hongyu Chen , Qiankun Xiong , Yong Nie , Kang Li , Jian Li

The 3D morphology and quantitative assessment of knee articular cartilages (i.e., femoral, tibial, and patellar cartilage) in magnetic resonance (MR) imaging is of great importance for knee radiographic osteoarthritis (OA) diagnostic…

Image and Video Processing · Electrical Eng. & Systems 2019-08-14 Chaowei Tan , Zhennan Yan , Shaoting Zhang , Kang Li , Dimitris N. Metaxas
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