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Diffusion models have recently emerged as powerful generative models in medical imaging. However, it remains a major challenge to combine these data-driven models with domain knowledge to guide brain imaging problems. In neuroimaging,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-19 Ana Lawry Aguila , Dina Zemlyanker , You Cheng , Sudeshna Das , Daniel C. Alexander , Oula Puonti , Annabel Sorby-Adams , W. Taylor Kimberly , Juan Eugenio Iglesias

Latent Diffusion Models (LDMs) enable high-quality image synthesis while avoiding excessive compute demands by training a diffusion model in a compressed lower-dimensional latent space. Here, we apply the LDM paradigm to high-resolution…

Computer Vision and Pattern Recognition · Computer Science 2023-12-29 Andreas Blattmann , Robin Rombach , Huan Ling , Tim Dockhorn , Seung Wook Kim , Sanja Fidler , Karsten Kreis

Diffusion magnetic resonance imaging (dMRI) is a crucial non-invasive technique for exploring the microstructure of the living human brain. Traditional hand-crafted and model-based tissue microstructure reconstruction methods often require…

Image and Video Processing · Electrical Eng. & Systems 2025-02-26 Xinrui Ma , Jian Cheng , Wenxin Fan , Ruoyou Wu , Yongquan Ye , Shanshan Wang

Reliable large-scale cell detection and segmentation is the fundamental first step to understanding biological processes in the brain. The ability to phenotype cells at scale can accelerate preclinical drug evaluation and system-level brain…

Computer Vision and Pattern Recognition · Computer Science 2023-01-03 Son T. Ly , Bai Lin , Hung Q. Vo , Dragan Maric , Badri Roysam , Hien V. Nguyen

Preterm birth disrupts the typical trajectory of cortical neurodevelopment, increasing the risk of cognitive and behavioral difficulties. However, outcomes vary widely, posing a significant challenge for early prediction. To address this,…

Neurons and Cognition · Quantitative Biology 2025-09-19 Zhenshan Xie , Levente Baljer , M. Jorge Cardoso , Emma Robinson

Mild cognitive impairment(MCI) is a precursor of Alzheimer's disease(AD), and the detection of MCI is of great clinical significance. Analyzing the structural brain networks of patients is vital for the recognition of MCI. However, the…

Neurons and Cognition · Quantitative Biology 2022-08-19 Heng Kong , Shuqiang Wang

Multimodal image fusion aims to integrate information from different imaging techniques to produce a comprehensive, detail-rich single image for downstream vision tasks. Existing methods based on local convolutional neural networks (CNNs)…

Computer Vision and Pattern Recognition · Computer Science 2025-02-04 Xinyu Xie , Yawen Cui , Tao Tan , Xubin Zheng , Zitong Yu

Diffusion MRI (dMRI) is an advanced imaging technique characterizing tissue microstructure and white matter structural connectivity of the human brain. The demand for high-quality dMRI data is growing, driven by the need for better…

Image and Video Processing · Electrical Eng. & Systems 2024-08-26 Xi Zhu , Wei Zhang , Yijie Li , Lauren J. O'Donnell , Fan Zhang

Several brain disorders can be detected by observing alterations in the brain's structural and functional connectivities. Neurological findings suggest that early diagnosis of brain disorders, such as mild cognitive impairment (MCI), can…

Neurons and Cognition · Quantitative Biology 2021-10-22 Alpay Tekin , Ahmed Nebli , Islem Rekik

Particle accelerators are complex systems that focus, guide, and accelerate intense charged particle beams to high energy. Beam diagnostics present a challenging problem due to limited non-destructive measurements, computationally demanding…

Accelerator Physics · Physics 2024-03-22 Mahindra Rautela , Alan Williams , Alexander Scheinker

Multi-modal neuroimaging analysis is crucial for a comprehensive understanding of brain function and pathology, as it allows for the integration of different imaging techniques, thus overcoming the limitations of individual modalities.…

Computer Vision and Pattern Recognition · Computer Science 2025-03-27 Weiheng Yao , Zhihan Lyu , Mufti Mahmud , Ning Zhong , Baiying Lei , Shuqiang Wang

Neural cellular automata represent an evolution of the traditional cellular automata model, enhanced by the integration of a deep learning-based transition function. This shift from a manual to a data-driven approach significantly increases…

Image and Video Processing · Electrical Eng. & Systems 2024-03-26 Andrea Menta , Alberto Archetti , Matteo Matteucci

Functional Magnetic Resonance Imaging (fMRI) is an imaging technique widely used to study human brain activity. fMRI signals in areas across the brain transiently synchronise and desynchronise their activity in a highly structured manner,…

Machine Learning · Computer Science 2025-08-12 Yiran Huang , Amirhossein Nouranizadeh , Christine Ahrends , Mengjia Xu

Convolutional neural networks and Transformer have made significant progresses in multi-modality medical image super-resolution. However, these methods either have a fixed receptive field for local learning or significant computational…

Computer Vision and Pattern Recognition · Computer Science 2025-04-15 Zexin Ji , Beiji Zou , Xiaoyan Kui , Sebastien Thureau , Su Ruan

Brain age prediction models have succeeded in predicting clinical outcomes in neurodegenerative diseases, but can struggle with tasks involving faster progressing diseases and low quality data. To enhance their performance, we employ a…

Diffusion models have become the most popular approach for high-quality image generation, but their high computational cost still remains a significant challenge. To address this problem, we propose U-Shape Mamba (USM), a novel diffusion…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Alex Ergasti , Filippo Botti , Tomaso Fontanini , Claudio Ferrari , Massimo Bertozzi , Andrea Prati

Accurate segmentation of 3D clinical medical images is critical in the diagnosis and treatment of spinal diseases. However, the inherent complexity of spinal anatomy and uncertainty inherent in current imaging technologies, poses…

Image and Video Processing · Electrical Eng. & Systems 2024-08-29 Zhiqing Zhang , Tianyong Liu , Guojia Fan , Bin Li , Qianjin Feng , Shoujun Zhou

The human brain undergoes rapid development during the third trimester of pregnancy. In this work, we model the neonatal development of the infant brain in this age range. As a basis, we use MR images of preterm- and term-birth neonates…

Image and Video Processing · Electrical Eng. & Systems 2024-08-19 Florentin Bieder , Paul Friedrich , Hélène Corbaz , Alicia Durrer , Julia Wolleb , Philippe C. Cattin

Acquiring high-quality annotated data for medical image segmentation is tedious and costly. Semi-supervised segmentation techniques alleviate this burden by leveraging unlabeled data to generate pseudo labels. Recently, advanced state space…

Computer Vision and Pattern Recognition · Computer Science 2025-08-20 Shumeng Li , Jian Zhang , Lei Qi , Luping Zhou , Yinghuan Shi , Yang Gao

Diffusion models (DMs) have achieved state-of-the-art results for image synthesis tasks as well as density estimation. Applied in the latent space of a powerful pretrained autoencoder (LDM), their immense computational requirements can be…

Computer Vision and Pattern Recognition · Computer Science 2022-10-21 Jeremias Traub