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Biological nervous systems are created in a fundamentally different way than current artificial neural networks. Despite its impressive results in a variety of different domains, deep learning often requires considerable engineering effort…

Neural and Evolutionary Computing · Computer Science 2023-07-18 Elias Najarro , Shyam Sudhakaran , Sebastian Risi

Spikes are the currency in central nervous systems for information transmission and processing. They are also believed to play an essential role in low-power consumption of the biological systems, whose efficiency attracts increasing…

Neural and Evolutionary Computing · Computer Science 2020-05-05 Qiang Yu , Shenglan Li , Huajin Tang , Longbiao Wang , Jianwu Dang , Kay Chen Tan

Many aspects of human reasoning, including language, require learning rules from very little data. Humans can do this, often learning systematic rules from very few examples, and combining these rules to form compositional rule-based…

Artificial Intelligence · Computer Science 2020-10-26 Maxwell I. Nye , Armando Solar-Lezama , Joshua B. Tenenbaum , Brenden M. Lake

Deep learning has seen remarkable developments over the last years, many of them inspired by neuroscience. However, the main learning mechanism behind these advances - error backpropagation - appears to be at odds with neurobiology. Here,…

Neurons and Cognition · Quantitative Biology 2018-10-29 João Sacramento , Rui Ponte Costa , Yoshua Bengio , Walter Senn

Given the stochastic nature of gene expression, genetically identical cells exposed to the same environmental inputs will produce different outputs. This heterogeneity has been hypothesized to have consequences for how cells are able to…

Molecular Networks · Quantitative Biology 2020-08-19 Manuel Razo-Mejia , Sarah Marzen , Griffin Chure , Rachel Taubman , Muir Morrison , Rob Phillips

Brain inspired neuromorphic computing has demonstrated remarkable advantages over traditional von Neumann architecture for its high energy efficiency and parallel data processing. However, the limited resolution of synaptic weights degrades…

Neural and Evolutionary Computing · Computer Science 2017-01-10 Yandan Wang , Wei Wen , Linghao Song , Hai Li

Recent work has observed an intriguing ''Neural Collapse'' phenomenon in well-trained neural networks, where the last-layer representations of training samples with the same label collapse into each other. This appears to suggest that the…

Machine Learning · Computer Science 2023-06-30 Yongyi Yang , Jacob Steinhardt , Wei Hu

In computer simulations of spiking neural networks, often it is assumed that every two neurons of the network are connected by a probability of 2\%, 20\% of neurons are inhibitory and 80\% are excitatory. These common values are based on…

Neurons and Cognition · Quantitative Biology 2015-03-06 Hamed Seyed-allaei

A sufficiently large information flux in recurrent neural networks, quantified by the mutual information between successive network states, is considered a prerequisite for rich information processing capabilities. This raises the question…

Neurons and Cognition · Quantitative Biology 2026-05-15 Claus Metzner , Ali Ghebleh , Karin Prebeck , Achim Schilling , Andreas Maier , Thomas Kinfe , Patrick Krauss

The automated analysis of microscopy images is a challenge in the context of single-cell tracking and quantification. This work has as goals the study of the performance of deep learning for segmenting microscopy images and the improvement…

Quantitative Methods · Quantitative Biology 2022-10-05 André O. Françani

We show that the unavoidable increase in neuronal response latency to ongoing stimulation serves as a nonuniform gradual stretching of neuronal circuit delay loops and emerges as an essential mechanism in the formation of various types of…

Neurons and Cognition · Quantitative Biology 2012-12-07 Roni Vardi , Reut Timor , Shimon Marom , Moshe Abeles , Ido Kanter

As the human brain develops, it increasingly supports coordinated control of neural activity. The mechanism by which white matter evolves to support this coordination is not well understood. We use a network representation of diffusion…

Current approaches to automated code generation often rely on monolithic models that lack real-time adaptability and scalability. This limitation is particularly evident in complex programming tasks that require dynamic adjustment and…

Machine Learning · Computer Science 2024-09-06 Gautham Ramachandran , Rick Yang

How far is neuroepithelial cell proliferation in the developing central nervous system a deterministic process? Or, to put it in a more precise way, how accurately can it be described by a deterministic mathematical model? To provide tracks…

Analysis of PDEs · Mathematics 2010-05-04 Jean Clairambault , Vladimir Flores , Benoit Perthame , Melina Rapacioli , Edmundo Rofman , Rafael Verdes

The basic units in our brain are neurons and each neuron has more than 1000 synapse connections. Synapse is the basic structure for information transfer in an ever-changing manner, and short-term plasticity allows synapses to perform…

Materials Science · Physics 2014-03-05 Li Qiang Zhu , Chang Jin Wan , Li Qiang Guo , Yi Shi , Qing Wan

The human brain achieves its remarkable computational prowess not despite its inherent non-ideal factors noise, heterogeneity, structural irregularities, decentralized plasticity, systematic errors, and chaotic dynamics but precisely…

Neurons and Cognition · Quantitative Biology 2026-03-24 Da-Zheng Feng , Hao-Xuan Du

Over the past decade there has been a growing interest in the development of parallel hardware systems for simulating large-scale networks of spiking neurons. Compared to other highly-parallel systems, GPU-accelerated solutions have the…

Neurons and Cognition · Quantitative Biology 2021-02-22 Bruno Golosio , Gianmarco Tiddia , Chiara De Luca , Elena Pastorelli , Francesco Simula , Pier Stanislao Paolucci

Thanks to novel, powerful brain activity recording techniques, we can create data-driven models from thousands of recording channels and large portions of the cortex, which can improve our understanding of brain-states neuromodulation and…

Early brain connectivity development consists of multiple stages: birth of neurons, their migration and the subsequent growth of axons and dendrites. Each stage occurs within a certain period of time depending on types of neurons and…

Neurons and Cognition · Quantitative Biology 2015-03-16 Sol Lim , Marcus Kaiser

Neural circuits must balance local connectivity constraints against the need for global integration. Here we introduce a minimal wiring rule motivated by synaptic crowding: as a neuron accumulates incoming connections, each additional…

Neurons and Cognition · Quantitative Biology 2026-03-23 Makoto Fukushima