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Neural circuits can be reconstructed from brain images acquired by serial section electron microscopy. Image analysis has been performed by manual labor for half a century, and efforts at automation date back almost as far. Convolutional…

Computer Vision and Pattern Recognition · Computer Science 2019-05-01 Kisuk Lee , Nicholas Turner , Thomas Macrina , Jingpeng Wu , Ran Lu , H. Sebastian Seung

A one-dimensional cellular automaton with a probabilistic evolution rule can generate stochastic surface growth in $(1 + 1)$ dimensions. Two such discrete models of surface growth are constructed from a probabilistic cellular automaton…

Statistical Mechanics · Physics 2015-06-25 Pratip Bhattacharyya

This work introduces a novel methodology for designing biologically plausible bursting neuron circuits using a minimal number of components. We hypothesize that to design circuits capable of bursting, the neuron circuit design must mimic a…

Hardware Architecture · Computer Science 2025-09-23 Amr Nabil , T. Nandha Kumar , Haider Abbas F. Almurib

We revisit the planning problem in the blocks world, and we implement a known heuristic for this task. Importantly, our implementation is biologically plausible, in the sense that it is carried out exclusively through the spiking of…

Artificial Intelligence · Computer Science 2022-11-22 Francesco d'Amore , Daniel Mitropolsky , Pierluigi Crescenzi , Emanuele Natale , Christos H. Papadimitriou

Brain function emerges from coordinated activity across anatomically connected regions, where structural connectivity (SC) -- the network of white matter pathways - provides the physical substrate for functional connectivity (FC) -- the…

Neurons and Cognition · Quantitative Biology 2025-07-09 Sam Frank Kelemen , Joaquín Gõni , Sérgio Pequito , Arian Ashourvan

Many recent generative models make use of neural networks to transform the probability distribution of a simple low-dimensional noise process into the complex distribution of the data. This raises the question of whether biological networks…

Neural and Evolutionary Computing · Computer Science 2018-02-07 Hesham Mostafa , Gert Cauwenberghs

Understanding the relation between cortical neuronal network structure and neuronal activity is a fundamental unresolved question in neuroscience, with implications to our understanding of the mechanism by which neuronal networks evolve…

Experimental results in recent years have shown that adult neurogenesis is a significant phenomenon in the mammalian brain. Little is known, however, about the functional role played by the generation and destruction of neurons in the…

Neurons and Cognition · Quantitative Biology 2009-11-10 Guillermo A. Cecchi , Marcelo O. Magnasco

By exploiting discrete signal processing and simulating brain neuron communication, Spiking Neural Networks (SNNs) offer a low-energy alternative to Artificial Neural Networks (ANNs). However, existing SNN models, still face high…

Neural and Evolutionary Computing · Computer Science 2024-11-12 Wenxuan Pan , Feifei Zhao , Bing Han , Haibo Tong , Yi Zeng

Conventional neural structures tend to communicate through analog quantities such as currents or voltages, however, as CMOS devices shrink and supply voltages decrease, the dynamic range of voltage/current-domain analog circuits becomes…

Neural and Evolutionary Computing · Computer Science 2025-05-15 Xiangyu Chen , Zolboo Byambadorj , Takeaki Yajima , Hisashi Inoue , Isao H. Inoue , Tetsuya Iizuka

We consider a fully-connected network of leaky integrate-and-fire neurons with spike-timing-dependent plasticity. The plasticity is controlled by a parameter representing the expected weight of a synapse between neurons that are firing…

Neurons and Cognition · Quantitative Biology 2011-09-23 Chun-Chung Chen , David Jasnow

The availability of large-scale neuronal population datasets necessitates new methods to model population dynamics and extract interpretable, scientifically translatable insights. Existing deep learning methods often overlook the biological…

Neurons and Cognition · Quantitative Biology 2024-11-14 Parsa Delavari , Ipek Oruc , Timothy H Murphy

The brain is an intricately structured organ responsible for the rich emergent dynamics that support the complex cognitive functions we enjoy as humans. With around $10^{11}$ neurons and $10^{15}$ synapses, understanding how the human brain…

Neurons and Cognition · Quantitative Biology 2019-02-12 Jason Z. Kim , Danielle S. Bassett

The surface morphology of the developing mammalian brain is crucial for understanding brain function and dysfunction. Computational modeling offers valuable insights into the underlying mechanisms for early brain folding. Recent findings…

Neurons and Cognition · Quantitative Biology 2024-09-06 Jixin Hou , Zhengwang Wu , Xianyan Chen , Li Wang , Dajiang Zhu , Tianming Liu , Gang Li , Xianqiao Wang

We present a new class of neurons, ARNs, which give a cross entropy on test data that is up to three times lower than the one achieved by carefully optimized LSTM neurons. The explanations for the huge improvements that often are achieved…

Neural and Evolutionary Computing · Computer Science 2022-07-11 Roland Olsson , Chau Tran , Lars Magnusson

Robust information representation and its persistent maintenance are fundamental for higher cognitive functions. Existing models employ distinct neural mechanisms to separately address noise-resistant processing or information maintenance,…

Neurons and Cognition · Quantitative Biology 2025-08-19 Jie Su , Weiwei Wang , Zhaotian Gu , Dahui Wang , Tianyi Qian

A computer model is described which is used to assess the dynamical complexity of a class of networks of spiking neurons with small-world properties. Networks are constructed by forming an initially segregated set of highly intra-connected…

Biological Physics · Physics 2009-11-13 Murray Shanahan

Spiking Neural Network (SNN) is the third generation of Neural Network (NN) mimicking the natural behavior of the brain. By processing based on binary input/output, SNNs offer lower complexity, higher density and lower power consumption.…

Neural and Evolutionary Computing · Computer Science 2020-03-24 Khanh N. Dang , Abderazek Ben Abdallah

Artificial Intelligence has looked into biological systems as a source of inspiration. Although there are many aspects of the brain yet to be discovered, neuroscience has found evidence that the connections between neurons continuously grow…

Neural and Evolutionary Computing · Computer Science 2020-10-29 Javier Lopez Randulfe , Leon Bonde Larsen

Spontaneous neuronal activity is a ubiquitous feature of cortex. Its spatiotemporal organization reflects past input and modulates future network output. Here we study whether a particular type of spontaneous activity is generated by a…

Neurons and Cognition · Quantitative Biology 2009-11-09 Woodrow L. Shew , Hongdian Yang , Thomas Petermann , Rajarshi Roy , Dietmar Plenz
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