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Related papers: Batch Effects In Brain Foundation Model Embeddings

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Deep learning has led to remarkable advancements in computational histopathology, e.g., in diagnostics, biomarker prediction, and outcome prognosis. Yet, the lack of annotated data and the impact of batch effects, e.g., systematic technical…

Machine Learning · Computer Science 2024-11-11 Jonah Kömen , Hannah Marienwald , Jonas Dippel , Julius Hense

Foundation models (FMs), large neural networks pretrained on extensive and diverse datasets, have revolutionized artificial intelligence and shown significant promise in medical imaging by enabling robust performance with limited labeled…

Image and Video Processing · Electrical Eng. & Systems 2025-06-17 Salah Ghamizi , Georgia Kanli , Yu Deng , Magali Perquin , Olivier Keunen

Brain foundation models (BFMs) have emerged as a transformative paradigm in computational neuroscience, offering a revolutionary framework for processing diverse neural signals across different brain-related tasks. These models leverage…

Machine Learning · Computer Science 2025-07-22 Xinliang Zhou , Chenyu Liu , Zhisheng Chen , Kun Wang , Yi Ding , Ziyu Jia , Qingsong Wen

Evaluating foundation models under appropriate adaptation settings is essential for understanding the quality and transferability of the learned representations. Recent EEG foundation models have demonstrated promising transfer capabilities…

Machine Learning · Computer Science 2026-05-28 Aditya Kommineni , Emily Zhou , Kleanthis Avramidis , Tiantian Feng , Shrikanth Narayanan

Foundation models (FMs) promise to generalize medical imaging, but their effectiveness varies. It remains unclear how pre-training domain (medical vs. general), paradigm (e.g., text-guided), and architecture influence embedding quality,…

A reliable foundation model of functional neuroimages is critical to promote clinical applications where the performance of current AI models is significantly impeded by a limited sample size. To that end, tremendous efforts have been made…

Machine Learning · Computer Science 2025-10-23 Ziquan Wei , Tingting Dan , Guorong Wu

Speech foundation models (SFMs) are increasingly hailed as powerful computational models of human speech perception. However, since their representations are inherently black-box, it remains unclear what drives their alignment with brain…

Neurons and Cognition · Quantitative Biology 2025-09-26 Riki Shimizu , Richard J. Antonello , Chandan Singh , Nima Mesgarani

Functional connectivity (FC) derived from resting-state fMRI plays a critical role in personalized predictions such as age and cognitive performance. However, applying foundation models(FM) to fMRI data remains challenging due to its high…

Neurons and Cognition · Quantitative Biology 2025-08-26 Yanwen Wang , Xinglin Zhao , Yijin Song , Xiaobo Liu , Yanrong Hao , Rui Cao , Xin Wen

Foundation Models have demonstrated significant success across various domains in Artificial Intelligence (AI), yet their capabilities for brainwave modeling remain unclear. In this paper, we comprehensively evaluate current Large Brainwave…

Machine Learning · Computer Science 2025-11-26 Na Lee , Konstantinos Barmpas , Yannis Panagakis , Dimitrios Adamos , Nikolaos Laskaris , Stefanos Zafeiriou

Modeling spatiotemporal brain dynamics from high-dimensional data, such as functional Magnetic Resonance Imaging (fMRI), is a formidable task in neuroscience. Existing approaches for fMRI analysis utilize hand-crafted features, but the…

Computer Vision and Pattern Recognition · Computer Science 2023-11-01 Peter Yongho Kim , Junbeom Kwon , Sunghwan Joo , Sangyoon Bae , Donggyu Lee , Yoonho Jung , Shinjae Yoo , Jiook Cha , Taesup Moon

Recent advances in large-scale pre-trained Electroencephalogram (EEG) models have shown great promise, driving progress in Brain-Computer Interfaces (BCIs) and healthcare applications. However, despite their success, many existing…

Machine Learning · Computer Science 2025-10-07 Konstantinos Barmpas , Na Lee , Yannis Panagakis , Dimitrios A. Adamos , Nikolaos Laskaris , Stefanos Zafeiriou

Supervised fine-tuning (SFT) on domain-specific data is the dominant approach for adapting foundation models to specialized tasks. However, it has been observed that SFT models tend to forget knowledge acquired during pretraining. In vision…

Artificial Intelligence · Computer Science 2025-06-03 Yifan Hao , Xingyuan Pan , Hanning Zhang , Chenlu Ye , Rui Pan , Tong Zhang

We present a foundation model for brain MRI that can work with different combinations of imaging sequences. The model uses one encoder with learnable modality embeddings, conditional layer normalization, and a masked autoencoding objective…

Computer Vision and Pattern Recognition · Computer Science 2025-11-06 Minh Sao Khue Luu , Bair N. Tuchinov

Mental and cognitive representations are believed to reside on low-dimensional, non-linear manifolds embedded within high-dimensional brain activity. Uncovering these manifolds is key to understanding individual differences in brain…

Machine Learning · Computer Science 2025-05-02 Eloy Geenjaar , Vince Calhoun

Recent advances in deep learning have made it possible to predict phenotypic measures directly from functional magnetic resonance imaging (fMRI) brain volumes, sparking significant interest in the neuroimaging community. However, existing…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Arunkumar Kannan , Martin A. Lindquist , Brian Caffo

Foundation models are transforming neuroscience but are often prohibitively large, data-hungry, and difficult to deploy. Here, we introduce BrainSymphony, a lightweight and parameter-efficient foundation model with plug-and-play integration…

Quantitative Methods · Quantitative Biology 2026-02-13 Moein Khajehnejad , Forough Habibollahi , Devon Stoliker , Adeel Razi

Trustworthy clinical AI requires that performance gains reflect genuine evidence integration rather than surface-level artifacts. We evaluate 12 open-weight vision-language models (VLMs) on binary classification across two clinical…

Artificial Intelligence · Computer Science 2026-03-31 Doan Nam Long Vu , Simone Balloccu

Foundation models pretrained on large-scale datasets via self-supervised learning demonstrate exceptional versatility across various tasks. Due to the heterogeneity and hard-to-collect medical data, this approach is especially beneficial…

Computational Engineering, Finance, and Science · Computer Science 2024-03-05 Yanwu Yang , Chenfei Ye , Guinan Su , Ziyao Zhang , Zhikai Chang , Hairui Chen , Piu Chan , Yue Yu , Ting Ma

Neural networks achieve state-of-the-art performance in many supervised learning tasks when the training data distribution matches the test data distribution. However, their performance drops significantly under domain (covariate) shift, a…

Computer Vision and Pattern Recognition · Computer Science 2024-09-13 Kerem Cekmeceli , Meva Himmetoglu , Guney I. Tombak , Anna Susmelj , Ertunc Erdil , Ender Konukoglu

An extensive line of work studies fairness interventions for network embeddings, but less is known about their baseline behavior. In this work, we ask: how do baseline embeddings (without fairness interventions) produce disparate effects at…

Social and Information Networks · Computer Science 2026-02-02 Gabriel Chuang , Augustin Chaintreau
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