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Embedding computation in molecular contexts incompatible with traditional electronics is expected to have wide ranging impact in synthetic biology, medicine, nanofabrication and other fields. A key remaining challenge lies in developing…

Neural and Evolutionary Computing · Computer Science 2020-07-01 Marko Vasic , Cameron Chalk , Sarfraz Khurshid , David Soloveichik

To combat adversarial spelling mistakes, we propose placing a word recognition model in front of the downstream classifier. Our word recognition models build upon the RNN semi-character architecture, introducing several new backoff…

Computation and Language · Computer Science 2019-08-30 Danish Pruthi , Bhuwan Dhingra , Zachary C. Lipton

The possibility to use Neural Networks for reconstruction of the energy deposited in the calorimetry system of the CMS detector is investigated. It is shown that using feed - forward neural network, good linearity, Gaussian energy…

High Energy Physics - Experiment · Physics 2009-10-31 J. Damgov , L. Litov

The field of molecular programming allows for the programming of the structure and behavior of matter at the molecular level, even to the point of encoding arbitrary computation. However, current approaches tend to be wasteful in terms of…

Emerging Technologies · Computer Science 2023-05-15 Hannah Earley

The nonlinearities found in molecular networks usually prevent mathematical analysis of network behaviour, which has largely been studied by numerical simulation. This can lead to difficult problems of parameter determination. However,…

Molecular Networks · Quantitative Biology 2012-07-17 R. L. Karp , M. Pérez Millán , T. Dasgupta , A. Dickenstein , J. Gunawardena

We present a novel framework for chemical learning based on Competitive Dimerization Networks (CDNs) - systems in which multiple molecular species, e.g. proteins or DNA/RNA oligomers, reversibly bind to form dimers. We show that these…

Statistical Mechanics · Physics 2025-06-18 Alexei V. Tkachenko , Bortolo Matteo Mognetti , Sergei Maslov

Recurrent Neural Networks (RNNs) have been a prominent concept within artificial intelligence. They are inspired by Biological Neural Networks (BNNs) and provide an intuitive and abstract representation of how BNNs work. Derived from the…

Neural and Evolutionary Computing · Computer Science 2017-03-09 Stefano Nichele , Andreas Molund

Nonlinear regression has been extensively employed in many computer vision problems (e.g., crowd counting, age estimation, affective computing). Under the umbrella of deep learning, two common solutions exist i) transforming nonlinear…

Computer Vision and Pattern Recognition · Computer Science 2019-08-27 Le Zhang , Zenglin Shi , Ming-Ming Cheng , Yun Liu , Jia-Wang Bian , Joey Tianyi Zhou , Guoyan Zheng , Zeng Zeng

Deep learning techniques have shown promise in many domain applications. This paper proposes a novel deep reservoir computing framework, termed deep recurrent stochastic configuration network (DeepRSCN) for modelling nonlinear dynamic…

Machine Learning · Computer Science 2024-10-29 Gang Dang , Dianhui Wang

Conformal prediction (CP) can convert any model's output into prediction sets guaranteed to include the true label with any user-specified probability. However, same as the model itself, CP is vulnerable to adversarial test examples…

Machine Learning · Computer Science 2024-07-15 Soroush H. Zargarbashi , Mohammad Sadegh Akhondzadeh , Aleksandar Bojchevski

The task of chemical reaction predictions (CRPs) plays a pivotal role in advancing drug discovery and material science. However, its effectiveness is constrained by the vast and uncertain chemical reaction space and challenges in capturing…

Machine Learning · Computer Science 2024-04-16 Pengfei Liu , Jun Tao , Zhixiang Ren

Accurately predicting chemical reaction outcomes and potential byproducts is a fundamental task of modern chemistry, enabling the efficient design of synthetic pathways and driving progress in chemical science. Reaction mechanism, which…

Chemical Physics · Physics 2025-03-14 Shuan Chen , Kye Sung Park , Taewan Kim , Sunkyu Han , Yousung Jung

Applying resolution-preserving blocks is a common practice to maximize information preservation in video prediction, yet their high memory consumption greatly limits their application scenarios. We propose CrevNet, a Conditionally…

Computer Vision and Pattern Recognition · Computer Science 2019-10-28 Wei Yu , Yichao Lu , Steve Easterbrook , Sanja Fidler

This paper studies the (discrete) \emph{chemical reaction network (CRN)} computational model that emerged in the last two decades as an abstraction for molecular programming. The correctness of CRN protocols is typically established under…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-07-04 Anne Condon , Yuval Emek , Noga Harlev

A physical neural network (PNN) has both the strong potential to solve machine learning tasks and intrinsic physical properties, such as high-speed computation and energy efficiency. Reservoir computing (RC) is an excellent framework for…

Chaotic Dynamics · Physics 2024-12-18 Tomoyuki Kubota , Yusuke Imai , Sumito Tsunegi , Kohei Nakajima

Recurrent Neural Networks (RNNs) produce state-of-art performance on many machine learning tasks but their demand on resources in terms of memory and computational power are often high. Therefore, there is a great interest in optimizing the…

Neural and Evolutionary Computing · Computer Science 2017-02-28 Joachim Ott , Zhouhan Lin , Ying Zhang , Shih-Chii Liu , Yoshua Bengio

In chemical reaction network theory, ordinary differential equations are used to model the temporal change of chemical species concentration. As the functional form of these ordinary differential equations systems is derived from an…

Molecular Networks · Quantitative Biology 2025-02-27 Anna C. M. Thöni , William E. Robinson , Yoram Bachrach , Wilhelm T. S. Huck , Tal Kachman

The thermodynamic and dynamical conditions necessary to observe indefinite growth in homogeneous open chemical reaction networks (CRNs) satisfying mass action kinetics were presented in Srinivas et al. (2023): Unimolecular CRNs can only…

Molecular Networks · Quantitative Biology 2024-12-05 Shesha Gopal Marehalli Srinivas , Francesco Avanzini , Massimiliano Esposito

Biochemical networks are used in computational biology, to model the static and dynamical details of systems involved in cell signaling, metabolism, and regulation of gene expression. Parametric and structural uncertainty, as well as…

Molecular Networks · Quantitative Biology 2014-10-15 Ovidiu Radulescu , Alexander N. Gorban , Andrei Zinovyev , Vincent Noel

We present here a combination of two networks, Recurrent Neural Networks (RNN) and Temporarily Convolutional Neural Networks (TCN) in de novo reaction generation using the novel Reaction Smiles-like representation of reactions (CGRSmiles)…

Machine Learning · Computer Science 2023-11-03 Andrei Buin , Hung Yi Chiang , S. Andrew Gadsden , Faraz A. Alderson