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Related papers: From Brain Models to Executable Digital Twins: Exe…

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The relationship between brain structure and function has been probed using a variety of approaches, but how the underlying structural connectivity of the human brain drives behavior is far from understood. To investigate the effect of…

Neurons and Cognition · Quantitative Biology 2018-11-15 Kanika Bansal , John D. Medaglia , Danielle S. Bassett , Jean M. Vettel , Sarah F. Muldoon

Artificial and natural neural network models are a new toolkit which could be potentially have been used for clarifying of complex brain functions. To attend this goal, such models need to be neurobiologically realistic. However, although…

Neurons and Cognition · Quantitative Biology 2022-07-08 Arsenii Onuchin

In this paper, we introduce a novel architecture to connecting adaptive learning and neural networks into an arbitrary machine's control system paradigm. Two consecutive Recurrent Neural Networks (RNNs) are used together to accurately model…

Machine Learning · Computer Science 2020-02-26 Srikanth Chandar , Harsha Sunder

The report describes the discussions from the Workshop on Mathematical Opportunities in Digital Twins (MATH-DT) from December 11-13, 2023, George Mason University. It illustrates that foundational Mathematical advances are required for…

Optimization and Control · Mathematics 2024-03-25 Harbir Antil

Future manufacturing requires complex systems that connect simulation platforms and virtualization with physical data from industrial processes. Digital twins incorporate a physical twin, a digital twin, and the connection between the two.…

Machine Learning · Computer Science 2021-09-20 Trier Mortlock , Deepan Muthirayan , Shih-Yuan Yu , Pramod P. Khargonekar , Mohammad A. Al Faruque

A digital twin is a virtual representation that accurately replicates its physical counterpart, fostering bi-directional real-time data exchange throughout the entire process lifecycle. For Laser Directed Energy Deposition of Wire…

Computational Engineering, Finance, and Science · Computer Science 2024-12-05 Maximilian Kannapinn , Fabian Roth , Oliver Weeger

Current methodologies typically integrate biophysical brain models with functional magnetic resonance imaging(fMRI) data - while offering millimeter-scale spatial resolution (0.5-2 mm^3 voxels), these approaches suffer from limited temporal…

Neurons and Cognition · Quantitative Biology 2025-07-17 Yubo Hou , Zhengxin Zhang , Ziyi Wang , Wenlian Lu , Jianfeng Feng , Taiping Zeng

Simulation frameworks have been key enablers for the development and validation of autonomous driving systems. However, existing methods struggle to comprehensively address the autonomy-oriented requirements of balancing: (i) dynamical…

Robotics · Computer Science 2026-02-23 Tanmay Vilas Samak , Chinmay Vilas Samak , Bing Li , Venkat Krovi

The concept of the Digital Twin, which in the context of this paper is the virtual representation of a production system or its components, can be used as a "digital playground" to master the increasing complexity of these assets. One of…

Computational Engineering, Finance, and Science · Computer Science 2024-10-15 Daniel Dittler , Valentin Stegmaier , Nasser Jazdi , Michael Weyrich

Generative models of brain activity have been instrumental in testing hypothesized mechanisms underlying brain dynamics against experimental datasets. Beyond capturing the key mechanisms underlying spontaneous brain dynamics, these models…

Neurons and Cognition · Quantitative Biology 2024-11-18 Rishikesan Maran , Eli J. Müller , Ben D. Fulcher

Intelligent agents must reason over both continuous dynamics and discrete representations to generate effective plans in complex environments. Previous studies have shown that symbolic abstractions can emerge from neural effect predictors…

Robotics · Computer Science 2026-03-10 Fatih Dogangun , Burcu Kilic , Serdar Bahar , Emre Ugur

Digital twins have emerged as a powerful technology for modeling and simulating complex systems across various domains (Fuller et al., 2020; Tao et al., 2019). As virtual representations of physical assets, processes, or systems, digital…

Software Engineering · Computer Science 2025-07-08 Gabriella Waters

We envision a future in which autonomous robots conduct scientific experiments in ways that are not only precise and repeatable, but also open, trustworthy, and transparent. To realize this vision, we present two key contributions: a…

Robotics · Computer Science 2025-08-18 Benjamin Alt , Mareike Picklum , Sorin Arion , Franklin Kenghagho Kenfack , Michael Beetz

Computational modeling plays an increasingly important role in neuroscience, highlighting the philosophical question of how computational models explain. In the context of neural network models for neuroscience, concerns have been raised…

Neurons and Cognition · Quantitative Biology 2021-04-15 Rosa Cao , Daniel Yamins

Despite the Digital Twin (DT) concept being in the industry for a long time, it remains ambiguous, unable to differentiate itself from information models, general computing, and simulation technologies. Part of this confusion stems from…

Human-Computer Interaction · Computer Science 2022-12-06 Ashwin Agrawal , Vishal Singh , Martin Fischer

Spatiotemporal flows of neural activity, such as traveling waves, have been observed throughout the brain since the earliest recordings; yet there is still little consensus on their functional role. Recent experiments and models have linked…

Neurons and Cognition · Quantitative Biology 2026-02-03 T. Anderson Keller , Lyle Muller , Terrence J. Sejnowski , Max Welling

Human cognitive performance is constrained by limited mental resources, yet continuous computational estimation of cognitive capacity dynamics remains an open challenge. We propose a theory-driven multimodal learning framework that models…

Machine Learning · Computer Science 2026-05-26 Yisak Debele , Henok Ademtew , Israel Goytom

The black-box nature of deep learning models prevents them from being completely trusted in domains like biomedicine. Most explainability techniques do not capture the concept-based reasoning that human beings follow. In this work, we…

Computer Vision and Pattern Recognition · Computer Science 2022-03-15 Avinash Kori , Parth Natekar , Ganapathy Krishnamurthi , Balaji Srinivasan

A central challenge in the computational modeling of neural dynamics is the trade-off between accuracy and simplicity. At the level of individual neurons, nonlinear dynamics are both experimentally established and essential for neuronal…

Digital twins (DTs) constitute a critical link between the real-world and the metaverse. To guarantee a robust connection between these two worlds, DTs should maintain accurate representations of the physical applications, while preserving…

Machine Learning · Computer Science 2022-04-12 Omar Hashash , Christina Chaccour , Walid Saad