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Related papers: From Brain Models to Executable Digital Twins: Exe…

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The growing importance of real-time simulation in the medical field has exposed the limitations and bottlenecks inherent in the digital representation of complex biological systems. This paper presents a novel methodology aimed at advancing…

Machine Learning · Computer Science 2024-12-17 Lucas Tesán , David González , Pedro Martins , Elías Cueto

Digital twins (DT) are often defined as a pairing of a physical entity and a corresponding virtual entity (VE), mimicking certain aspects of the former depending on the use-case. In recent years, this concept has facilitated numerous…

Digital twins promise to enhance robotic manipulation by maintaining a consistent link between real-world perception and simulation. However, most existing systems struggle with the lack of a unified model, complex dynamic interactions, and…

Robotics · Computer Science 2026-03-06 Yichen Cai , Paul Jansonnie , Cristiana de Farias , Oleg Arenz , Jan Peters

Actionable Cognitive Twins are the next generation Digital Twins enhanced with cognitive capabilities through a knowledge graph and artificial intelligence models that provide insights and decision-making options to the users. The knowledge…

Artificial Intelligence · Computer Science 2021-03-25 Jože M. Rožanec , Jinzhi Lu , Jan Rupnik , Maja Škrjanc , Dunja Mladenić , Blaž Fortuna , Xiaochen Zheng , Dimitris Kiritsis

Simulating glucose dynamics in individuals with type 1 diabetes (T1D) is critical for developing personalized treatments and supporting data-driven clinical decisions. Existing models often miss key physiological aspects and are difficult…

Quantitative Methods · Quantitative Biology 2026-04-16 Valentina Roquemen-Echeverri , Taisa Kushner , Peter G. Jacobs , Clara Mosquera-Lopez

Scientific modeling faces a tradeoff between the interpretability of mechanistic theory and the predictive power of machine learning. While existing hybrid approaches have made progress by incorporating domain knowledge into machine…

Machine Learning · Computer Science 2026-04-15 Carson Dudley , Reiden Magdaleno , Christopher Harding , Marisa Eisenberg

Supply chain management is growing increasingly complex due to globalization, evolving market demands, and sustainability pressures, yet traditional systems struggle with fragmented data and limited analytical capabilities. Graph-based…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-04-08 Azmine Toushik Wasi , Mahfuz Ahmed Anik , Abdur Rahman , Md. Iqramul Hoque , MD Shafikul Islam , Md Manjurul Ahsan

We articulate the design imperatives for machine-learning based digital twins for nonlinear dynamical systems subject to external driving, which can be used to monitor the ``health'' of the target system and anticipate its future collapse.…

Adaptation and Self-Organizing Systems · Physics 2022-10-13 Ling-Wei Kong , Yang Weng , Bryan Glaz , Mulugeta Haile , Ying-Cheng Lai

Developing embodied AI for intelligent surgical systems requires safe, controllable environments for continual learning and evaluation. However, safety regulations and operational constraints in operating rooms (ORs) limit agents from…

The real-time supervision of production processes is a common challenge across several industries. It targets process component monitoring and its predictive maintenance in order to ensure safety, uninterrupted production and maintain high…

Machine Learning · Computer Science 2026-02-27 Osimone Imhogiemhe , Yoann Jus , Hubert Lejeune , Saïd Moussaoui

A digital twin is a surrogate model that has the main feature to mirror the original process behavior. Associating the dynamical process with a digital twin model of reduced complexity has the significant advantage to map the dynamics with…

Numerical Analysis · Mathematics 2024-03-19 Diana Alina Bistrian , Omer San , Ionel Michael Navon

Digital Twins (DTs) represent digital counterparts of physical systems, assets, or processes, referred to as the actual twin (AT). DTs integrate heterogeneous data, models, and semantic technologies to support monitoring, simulation,…

Software Engineering · Computer Science 2026-05-21 Faima Abbasi , Jean-Sébastien Sottet , Cedric Pruski

In recent years, advances in neuroscience and artificial intelligence have paved the way for unprecedented opportunities for understanding the complexity of the brain and its emulation by computational systems. Cutting-edge advancements in…

Neurons and Cognition · Quantitative Biology 2024-04-19 Hui Xiong , Congying Chu , Lingzhong Fan , Ming Song , Jiaqi Zhang , Yawei Ma , Ruonan Zheng , Junyang Zhang , Zhengyi Yang , Tianzi Jiang

Robotic systems have become integral to smart environments, enabling applications ranging from urban surveillance and automated agriculture to industrial automation. However, their effective operation in dynamic settings - such as smart…

Current neural interfaces such as brain-computer interfaces (BCIs) face several fundamental challenges, including frequent recalibration due to neuroplasticity and session-to-session variability, real-time processing latency, limited…

Human-Computer Interaction · Computer Science 2026-01-06 Mohammad Mahdi Habibi Bina , Sepideh Baghernezhad , Mohammad Reza Daliri , Mohammad Hassan Moradi

Digital twins are models of real-world systems that can simulate their dynamics in response to potential actions. In complex settings, the state and action variables, and available data and knowledge relevant to a system can constantly…

Computation and Language · Computer Science 2025-07-23 Harry Amad , Nicolás Astorga , Mihaela van der Schaar

Human digital twin (HDT) is an emerging paradigm that bridges physical twins (PTs) with powerful virtual twins (VTs) for assisting complex task executions in human-centric services. In this paper, we study a two-timescale online…

Networking and Internet Architecture · Computer Science 2024-01-31 Yuye Yang , You Shi , Changyan Yi , Jun Cai , Jiawen Kang , Dusit Niyato , Xuemin , Shen

This paper presents a proof-of-concept digital twin framework for simulation-driven diabetes modeling using benchmark clinical data, synthetic temporal augmentation, and illustrative continuous glucose monitoring (CGM) analysis. Unlike…

Machine Learning · Computer Science 2026-05-13 Zarrin Monirzadeh

Biological brains demonstrate complex neural activity, where neural dynamics are critical to how brains process information. Most artificial neural networks ignore the complexity of individual neurons. We challenge that paradigm. By…

Machine Learning · Computer Science 2025-10-06 Luke Darlow , Ciaran Regan , Sebastian Risi , Jeffrey Seely , Llion Jones

Pedestrian dynamics simulates the fine-scaled trajectories of individuals in a crowd. It has been used to suggest public health interventions to reduce infection risk in important components of air travel, such as during boarding and in…

Computers and Society · Computer Science 2024-10-21 Ashok Srinivasan , Satkkeerthi Sriram , Sirish Namilae , Andrew Arash Mahyari