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Is there a canonical way to think of agency beyond reward maximisation? In this paper, we show that any type of behaviour complying with physically sound assumptions about how macroscopic biological agents interact with the world…

Artificial Intelligence · Computer Science 2024-01-24 Lancelot Da Costa , Samuel Tenka , Dominic Zhao , Noor Sajid

Scientific algorithm discovery is iterative: hypotheses are proposed, implemented, stress-tested, and revised. Current LLM-guided search systems accelerate proposal generation, but often under-represent scientific structure by optimizing…

Machine Learning · Computer Science 2026-04-02 Youssef Mroueh , Carlos Fonseca , Brian Belgodere , David Cox

Recent advancements in agentic test-time scaling allow models to gather environmental feedback before committing to final actions. A key limitation of existing methods is that they typically employ undifferentiated exploration strategies,…

Artificial Intelligence · Computer Science 2026-05-13 Xingyuan Hua , Sheng Yue , Ju Ren

Active inference is a mathematical framework for understanding how agents (biological or artificial) interact with their environments, enabling continual adaptation and decision-making. It combines Bayesian inference and free energy…

Artificial Intelligence · Computer Science 2024-10-02 Rithvik Prakki

Multimodal Large Language Models have shown promising capabilities in bridging visual and textual reasoning, yet their reasoning capabilities in Open-Vocabulary Human-Object Interaction (OV-HOI) are limited by cross-modal hallucinations and…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Zhenlong Yuan , Yue Wang , Dapeng Zhang , Kejin Cui , Rui Chen , Jing Tang , Lei Sun , Hongwei Yu , Chengxuan Qian , Xiangxiang Chu , Shuo Li , Yuyin Zhou

Autonomous AI is no longer a hard-to-reach concept, it enables the agents to move beyond executing tasks to independently addressing complex problems, adapting to change while handling the uncertainty of the environment. However, what makes…

Neurons and Cognition · Quantitative Biology 2025-05-12 Zinan Liu , Haoran Li , Jingyi Lu , Gaoyuan Ma , Xu Hong , Giovanni Iacca , Arvind Kumar , Shaojun Tang , Lin Wang

Modern analytics systems are fundamentally reactive, requiring users to define queries over increasingly complex and continuously evolving data. In real-time streaming environments, this paradigm breaks down, as the space of potential…

Artificial Intelligence · Computer Science 2026-05-28 Gaetano Rossiello , Dharmashankar Subramanian

Agentic systems for drug discovery have demonstrated autonomous synthesis planning, literature mining, and molecular design. We ask how well they generalize. Evaluating six frameworks against 15 task classes drawn from peptide therapeutics,…

Quantitative Methods · Quantitative Biology 2026-02-12 Edward Wijaya

Causal discovery through experimentation and intervention is fundamental to robust problem solving. It requires not just updating beliefs within a fixed framework but revising the hypothesis space itself, a capacity current AI agents lack…

Artificial Intelligence · Computer Science 2026-04-23 John Alderete , Sebastian Benthal , Connie Xu , John Xing

The demands on visual recognition systems do not end with the complexity offered by current large-scale image datasets, such as ImageNet. In consequence, we need curious and continuously learning algorithms that actively acquire knowledge…

Computer Vision and Pattern Recognition · Computer Science 2016-12-20 Christoph Käding , Erik Rodner , Alexander Freytag , Joachim Denzler

The active inference framework (AIF) is a promising new computational framework grounded in contemporary neuroscience that can produce human-like behavior through reward-based learning. In this study, we test the ability for the AIF to…

Neurons and Cognition · Quantitative Biology 2022-11-21 Zhizhuo Yang , Gabriel J. Diaz , Brett R. Fajen , Reynold Bailey , Alexander Ororbia

Designing agent that can autonomously discover and learn a diversity of structures and skills in unknown changing environments is key for lifelong machine learning. A central challenge is how to learn incrementally representations in order…

Machine Learning · Computer Science 2020-05-14 Mayalen Etcheverry , Pierre-Yves Oudeyer , Chris Reinke

We show that multi-agent systems guided by vision-language models (VLMs) improve end-to-end autonomous scientific discovery. By treating plots as verifiable checkpoints, a VLM-as-a-judge evaluates figures against dynamically generated…

Computation and Language · Computer Science 2025-11-19 Kahaan Gandhi , Boris Bolliet , Inigo Zubeldia

Explanations for AI models in high-stakes domains like medicine often lack verifiability, which can hinder trust. To address this, we propose an interactive agent that produces explanations through an auditable sequence of actions. The…

Artificial Intelligence · Computer Science 2025-11-04 Yuhang Huang , Zekai Lin , Fan Zhong , Lei Liu

Modern vision-language models (VLMs) deliver impressive predictive accuracy yet offer little insight into 'why' a decision is reached, frequently hallucinating facts, particularly when encountering out-of-distribution data. Neurosymbolic…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Sanchit Sinha , Guangzhi Xiong , Zhenghao He , Aidong Zhang

Active inference is a mathematical framework which originated in computational neuroscience as a theory of how the brain implements action, perception and learning. Recently, it has been shown to be a promising approach to the problems of…

Despite the success of Vision-Language Models (VLMs), misleading charts remain a significant challenge due to their deceptive visual structures and distorted data representations. We present ChartCynics, an agentic dual-path framework…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Yanjie Zhang , Yafei Li , Rui Sheng , Zixin Chen , Yanna Lin , Huamin Qu , Lei Chen , Yushi Sun

Nanomedicine research spans delivery chemistry, immunology, imaging, biomaterials, and disease-specific translational science, yet its conceptual design space remains fragmented across a large and heterogeneous literature. To date,…

Active hypothesis testing is a thoroughly studied problem that finds numerous applications in wireless communications and sensor networks. In this paper, we focus on one centralized and one decentralized problem of active hypothesis testing…

Artificial Intelligence · Computer Science 2025-08-26 George Stamatelis , Angelos-Nikolaos Kanatas , Ioannis Asprogerakas , George C. Alexandropoulos

Active visual exploration aims to assist an agent with a limited field of view to understand its environment based on partial observations made by choosing the best viewing directions in the scene. Recent methods have tried to address this…

Computer Vision and Pattern Recognition · Computer Science 2021-08-27 Soroush Seifi , Abhishek Jha , Tinne Tuytelaars