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The advent of foundation models (FMs) as an emerging suite of AI techniques has struck a wave of opportunities in computational healthcare. The interactive nature of these models, guided by pre-training data and human instructions, has…

Machine Learning · Computer Science 2026-04-30 Yunkun Zhang , Jin Gao , Zheling Tan , Lingfeng Zhou , Kexin Ding , Mu Zhou , Shaoting Zhang , Dequan Wang

As AI workloads increase in scope, generalization capability becomes challenging for small task-specific models and their demand for large amounts of labeled training samples increases. On the contrary, Foundation Models (FMs) are trained…

Artificial Intelligence · Computer Science 2024-04-19 Aristeidis Tsaris , Philipe Ambrozio Dias , Abhishek Potnis , Junqi Yin , Feiyi Wang , Dalton Lunga

Following its success for vision and text, the "foundation model" (FM) paradigm -- pretraining large models on massive data, then fine-tuning on target tasks -- has rapidly expanded to domains in the sciences, engineering, healthcare, and…

Machine Learning · Computer Science 2025-03-24 Zongzhe Xu , Ritvik Gupta , Wenduo Cheng , Alexander Shen , Junhong Shen , Ameet Talwalkar , Mikhail Khodak

Artificial Intelligence for scientific applications increasingly requires training large models on data that cannot be centralized due to privacy constraints, data sovereignty, or the sheer volume of data generated. Federated learning (FL)…

Machine Learning · Computer Science 2026-03-23 Yijiang Li , Zilinghan Li , Kyle Chard , Ian Foster , Todd Munson , Ravi Madduri , Kibaek Kim

Tech-leading organizations are embracing the forthcoming artificial intelligence revolution. Intelligent systems are replacing and cooperating with traditional software components. Thus, the same development processes and standards in…

Software Engineering · Computer Science 2021-06-03 Mark Haakman , Luís Cruz , Hennie Huijgens , Arie van Deursen

Foundation model, which is pre-trained on broad data and is able to adapt to a wide range of tasks, is advancing healthcare. It promotes the development of healthcare artificial intelligence (AI) models, breaking the contradiction between…

Computers and Society · Computer Science 2024-04-05 Yuting He , Fuxiang Huang , Xinrui Jiang , Yuxiang Nie , Minghao Wang , Jiguang Wang , Hao Chen

The role of artificial intelligence (AI) in pathology has evolved from aiding diagnostics to uncovering predictive morphological patterns in whole slide images (WSIs). Recently, foundation models (FMs) leveraging self-supervised…

The strategic importance of artificial intelligence is driving a global push toward Sovereign AI initiatives. Nationwide governments are increasingly developing dedicated infrastructures, called AI Factories (AIF), to achieve technological…

Significant investments to upgrade and construct large-scale scientific facilities demand commensurate investments in R&D to design algorithms and computing approaches to enable scientific and engineering breakthroughs in the big data era.…

Foundation models are deep neural networks (such as GPT-5, Gemini~3, and Opus~4) trained on large datasets that can perform diverse downstream tasks -- text and code generation, question answering, summarization, image classification, and…

Machine Learning · Computer Science 2026-05-01 Logan G Wright , Tianyu Wang , Tatsuhiro Onodera , Peter L. McMahon

Biological foundation models (BioFMs), pretrained on large-scale biological sequences, have recently shown strong potential in providing meaningful representations for diverse downstream bioinformatics tasks. However, such models often rely…

Machine Learning · Computer Science 2026-02-10 Yifan Wu , Jiyue Jiang , Xichen Ye , Yiqi Wang , Chang Zhou , Yitao Xu , Jiayang Chen , He Hu , Weizhong Zhang , Cheng Jin , Jiao Yuan , Yu Li

While the pretraining of Foundation Models (FMs) for remote sensing (RS) imagery is on the rise, models remain restricted to a few hundred million parameters. Scaling models to billions of parameters has been shown to yield unprecedented…

Computer Vision and Pattern Recognition · Computer Science 2024-10-29 Philipe Dias , Aristeidis Tsaris , Jordan Bowman , Abhishek Potnis , Jacob Arndt , H. Lexie Yang , Dalton Lunga

Generative pretraining (the "GPT" in ChatGPT) enables language models to learn from vast amounts of internet text without human supervision. This approach has driven breakthroughs across AI by allowing deep neural networks to learn from…

Neurons and Cognition · Quantitative Biology 2025-09-23 Thomas Serre , Ellie Pavlick

The rapid rise of large language models (LLMs) has been driving an enormous demand for AI inference infrastructure, mainly powered by high-end GPUs. While these accelerators offer immense computational power, they incur high capital and…

Artificial Intelligence · Computer Science 2025-10-01 Jovan Stojkovic , Chaojie Zhang , Íñigo Goiri , Ricardo Bianchini

Artificial intelligence (AI)-driven electronic design automation (EDA) techniques have been extensively explored for VLSI circuit design applications. Most recently, foundation AI models for circuits have emerged as a new technology trend.…

Hardware Architecture · Computer Science 2025-04-08 Wenji Fang , Jing Wang , Yao Lu , Shang Liu , Yuchao Wu , Yuzhe Ma , Zhiyao Xie

Bioinformatics has witnessed a paradigm shift with the increasing integration of artificial intelligence (AI), particularly through the adoption of foundation models (FMs). These AI techniques have rapidly advanced, addressing historical…

Quantitative Methods · Quantitative Biology 2024-02-08 Qing Li , Zhihang Hu , Yixuan Wang , Lei Li , Yimin Fan , Irwin King , Le Song , Yu Li

Foundation models (FMs) are general-purpose artificial intelligence (AI) models that have recently enabled multiple brand-new generative AI applications. The rapid advances in FMs serve as an important contextual backdrop for the vision of…

Networking and Internet Architecture · Computer Science 2024-05-08 Zihan Chen , Howard H. Yang , Y. C. Tay , Kai Fong Ernest Chong , Tony Q. S. Quek

Generative AI, in particular large transformer models, are increasingly driving HPC system design in science and industry. We analyze performance characteristics of such transformer models and discuss their sensitivity to the transformer…

Foundational Models (FMs) are gaining increasing attention in the biomedical AI ecosystem due to their ability to represent and contextualize multimodal biomedical data. These capabilities make FMs a valuable tool for a variety of tasks,…

The integration of Foundation Models (FMs) with Federated Learning (FL) presents a transformative paradigm in Artificial Intelligence (AI). This integration offers enhanced capabilities, while addressing concerns of privacy, data…

Machine Learning · Computer Science 2024-09-10 Chao Ren , Han Yu , Hongyi Peng , Xiaoli Tang , Bo Zhao , Liping Yi , Alysa Ziying Tan , Yulan Gao , Anran Li , Xiaoxiao Li , Zengxiang Li , Qiang Yang
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