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Data-Centric Foundation Models in Computational Healthcare: A Survey

Machine Learning 2026-04-30 v3 Artificial Intelligence

Abstract

The advent of foundation models (FMs) as an emerging suite of AI techniques has struck a wave of opportunities in computational healthcare. The interactive nature of these models, guided by pre-training data and human instructions, has ignited a data-centric AI paradigm that emphasizes better data characterization, quality, and scale. In healthcare AI, obtaining and processing high-quality clinical data records has been a longstanding challenge, encompassing data quantity, annotation, patient privacy, and ethics. In this survey, we investigate a wide range of data-centric approaches in the FM era (from model pre-training to inference) towards improving the healthcare workflow. We discuss key perspectives in AI security, assessment, and alignment with human values. Finally, we offer a promising outlook on FM-based analytics to enhance patient outcomes and clinical workflows in the evolving landscape of healthcare and medicine. We provide an up-to-date list of healthcare-related foundation models and datasets at https://github.com/Yunkun-Zhang/Data-Centric-FM-Healthcare.

Keywords

Cite

@article{arxiv.2401.02458,
  title  = {Data-Centric Foundation Models in Computational Healthcare: A Survey},
  author = {Yunkun Zhang and Jin Gao and Zheling Tan and Lingfeng Zhou and Kexin Ding and Mu Zhou and Shaoting Zhang and Dequan Wang},
  journal= {arXiv preprint arXiv:2401.02458},
  year   = {2026}
}

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Published in ACM Computing Surveys

R2 v1 2026-06-28T14:08:59.098Z