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Summary: R and Matlab are two high-level scientific programming languages which are frequently applied in computational biology. To extend the wide variety of available and approved implementations, we present the Rcall interface which runs…

Programming Languages · Computer Science 2021-06-16 Janine Egert , Clemens Kreutz

Large language Models (LLMs) are usually used to answer questions, but many high-stakes applications (e.g., tutoring, clinical support) require the complementary skill of asking questions: detecting missing information, requesting…

Artificial Intelligence · Computer Science 2026-01-07 Rajeev Bhatt Ambati , Tianyi Niu , Aashu Singh , Shlok Mishra , Snigdha Chaturvedi , Shashank Srivastava

Large language models (LLMs) have demonstrated strong reasoning and tool-use capabilities, yet they often fail in real-world tool-interactions due to incorrect parameterization, poor tool selection, or misinterpretation of user intent.…

Artificial Intelligence · Computer Science 2025-09-23 Hy Dang , Tianyi Liu , Zhuofeng Wu , Jingfeng Yang , Haoming Jiang , Tao Yang , Pei Chen , Zhengyang Wang , Helen Wang , Huasheng Li , Bing Yin , Meng Jiang

Voice assistants increasingly rely on Speech Language Models (SpeechLMs) to interpret spoken queries and execute complex tasks, yet existing benchmarks lack domain breadth, acoustic diversity, and compositional reasoning complexity to…

We present Natural Language Tools (NLT), a framework that replaces programmatic JSON tool calling in large language models (LLMs) with natural language outputs. By decoupling tool selection from response generation, NLT eliminates task…

Computation and Language · Computer Science 2025-10-17 Reid T. Johnson , Michelle D. Pain , Jordan D. West

Despite the advancements of open-source large language models (LLMs), e.g., LLaMA, they remain significantly limited in tool-use capabilities, i.e., using external tools (APIs) to fulfill human instructions. The reason is that current…

Fine-tuning large language models (LLMs) with domain-specific instructions has emerged as an effective method to enhance their domain-specific understanding. Yet, there is limited work that examines the core characteristics acquired during…

Computation and Language · Computer Science 2023-12-27 Varun Nathan , Ayush Kumar , Digvijay Ingle , Jithendra Vepa

Large language model (LLM)-based agents that reason, plan, and act through tools, memory, and structured interaction are emerging as a promising paradigm for automating complex workflows. Recent systems such as OpenClaw and Claude Code…

Information Retrieval · Computer Science 2026-05-27 Yingli Zhou , Wang Shu , Yaodong Su , Wenchuan Du , Yixiang Fang , Xuemin Lin

Large language models (LLMs) have shown impressive promise in code generation, yet their progress remains limited by the shortage of large-scale datasets that are both diverse and well-aligned with human reasoning. Most existing resources…

Machine Learning · Computer Science 2025-10-28 Amal Abed , Ivan Lukic , Jörg K. H. Franke , Frank Hutter

Large language models (LLMs) demonstrate strong mathematical reasoning, but reliance on closed-source APIs for OR tasks raises privacy concerns, and training open-source models from scratch incurs high compute costs. We introduce…

Artificial Intelligence · Computer Science 2025-10-03 Jianzhang Zhang , Jialong Zhou , Chuang Liu

Large Language Models are now key assistants in human decision-making processes. However, a common note always seems to follow: "LLMs can make mistakes. Be careful with important info." This points to the reality that not all outputs from…

Computation and Language · Computer Science 2025-05-16 Longchao Da , Parth Mitesh Shah , Kuan-Ru Liou , Jiaxing Zhang , Hua Wei

Open-Domain Question Answering (ODQA) aims to answer questions without explicitly providing specific background documents. This task becomes notably challenging in a zero-shot setting where no data is available to train tailored…

Computation and Language · Computer Science 2024-03-29 Junlong Li , Jinyuan Wang , Zhuosheng Zhang , Hai Zhao

Recently, various methods have been proposed to create open-domain conversational agents with Large Language Models (LLMs). These models are able to answer user queries, but in a one-way Q&A format rather than a true conversation.…

Computation and Language · Computer Science 2024-07-02 Ahmed Njifenjou , Virgile Sucal , Bassam Jabaian , Fabrice Lefèvre

In this paper, we investigate the use of large language models (LLMs) like ChatGPT for document-grounded response generation in the context of information-seeking dialogues. For evaluation, we use the MultiDoc2Dial corpus of task-oriented…

Computation and Language · Computer Science 2023-09-22 Norbert Braunschweiler , Rama Doddipatla , Simon Keizer , Svetlana Stoyanchev

Large Language Models (LLMs) increasingly support culturally sensitive decision making, yet often exhibit misalignment due to skewed pretraining data and the absence of structured value representations. Existing methods can steer outputs,…

Computation and Language · Computer Science 2026-02-02 Wonduk Seo , Wonseok Choi , Junseo Koh , Juhyeon Lee , Hyunjin An , Minhyeong Yu , Jian Park , Qingshan Zhou , Seunghyun Lee , Yi Bu

Recent advancements in Large Language Models (LLMs) have demonstrated exceptional capabilities in natural language understanding and generation. While these models excel in general complex reasoning tasks, they still face challenges in…

Artificial Intelligence · Computer Science 2024-10-25 Graziano A. Manduzio , Federico A. Galatolo , Mario G. C. A. Cimino , Enzo Pasquale Scilingo , Lorenzo Cominelli

Cell type annotation is a key task in analyzing the heterogeneity of single-cell RNA sequencing data. Although recent foundation models automate this process, they typically annotate cells independently, without considering batch-level…

Computation and Language · Computer Science 2025-06-04 Yin Fang , Qiao Jin , Guangzhi Xiong , Bowen Jin , Xianrui Zhong , Siru Ouyang , Aidong Zhang , Jiawei Han , Zhiyong Lu

Although Large Language Models (LLMs) have demonstrated extraordinary capabilities in many domains, they still have a tendency to hallucinate and generate fictitious responses to user requests. This problem can be alleviated by augmenting…

Information Retrieval · Computer Science 2023-06-09 Jiongnan Liu , Jiajie Jin , Zihan Wang , Jiehan Cheng , Zhicheng Dou , Ji-Rong Wen

Recent advancements in large language models (LLMs) have shown promise in medical applications such as disease diagnosis and treatment planning. However, most existing medical LLMs struggle with the deep reasoning required for complex…

Computation and Language · Computer Science 2025-07-31 Hongzhou Yu , Tianhao Cheng , Yingwen Wang , Wen He , Qing Wang , Ying Cheng , Yuejie Zhang , Rui Feng , Xiaobo Zhang

Using tools by Large Language Models (LLMs) is a promising avenue to extend their reach beyond language or conversational settings. The number of tools can scale to thousands as they enable accessing sensory information, fetching updated…

Information Retrieval · Computer Science 2024-12-06 Mohammad Kachuee , Sarthak Ahuja , Vaibhav Kumar , Puyang Xu , Xiaohu Liu
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