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Medical dialogue systems (MDS) have emerged as crucial online platforms for enabling multi-turn, context-aware conversations with patients. However, existing MDS often struggle to (1) identify relevant medical knowledge and (2) generate…

Computation and Language · Computer Science 2025-06-13 Hongda Sun , Jiaren Peng , Wenzhong Yang , Liang He , Bo Du , Rui Yan

The automation of the medical evidence acquisition and diagnosis process has recently attracted increasing attention in order to reduce the workload of doctors and democratize access to medical care. However, most works proposed in the…

Computation and Language · Computer Science 2022-10-14 Arsene Fansi Tchango , Rishab Goel , Julien Martel , Zhi Wen , Gaetan Marceau Caron , Joumana Ghosn

Large Language Models (LLMs) have shown promising performance on diverse medical benchmarks, highlighting their potential in supporting real-world clinical tasks. Retrieval-Augmented Generation (RAG) has emerged as a key approach for…

Computation and Language · Computer Science 2025-09-30 Kaishuai Xu , Wenjun Hou , Yi Cheng , Wenjie Li

Ensuring factual consistency and reliable reasoning remains a critical challenge for medical vision-language models. We introduce MEDFACT-R1, a two-stage framework that integrates external knowledge grounding with reinforcement learning to…

Computer Vision and Pattern Recognition · Computer Science 2025-09-19 Gengliang Li , Rongyu Chen , Bin Li , Linlin Yang , Guodong Ding

The effectiveness of Reinforcement Learning (RL) in Large Language Models (LLMs) depends on the nature and diversity of the data used before and during RL. In particular, reasoning problems can often be approached in multiple ways that rely…

Artificial Intelligence · Computer Science 2026-05-12 Aswin RRV , Jacob Dineen , Divij Handa , Mihir Parmar , Ben Zhou , Swaroop Mishra , Chitta Baral

Large Language Models (LLMs) have achieved significant advancements, but the increasing complexity of tasks and higher performance demands highlight the need for continuous improvement. Some approaches utilize synthetic data generated by…

Artificial Intelligence · Computer Science 2025-06-23 Haokun Zhao , Jinyi Han , Jiaqing Liang , Yanghua Xiao , Xiaojun Meng , Jiansheng Wei

Large Language Models (LLMs) often struggle with problems that require multi-step reasoning. For small-scale open-source models, Reinforcement Learning with Verifiable Rewards (RLVR) fails when correct solutions are rarely sampled even…

Computation and Language · Computer Science 2026-03-02 Yihe Deng , I-Hung Hsu , Jun Yan , Zifeng Wang , Rujun Han , Gufeng Zhang , Yanfei Chen , Wei Wang , Tomas Pfister , Chen-Yu Lee

Inference-time scaling has attracted much attention which significantly enhance the performance of Large Language Models (LLMs) in complex reasoning tasks by increasing the length of Chain-of-Thought. These longer intermediate reasoning…

Computation and Language · Computer Science 2025-05-21 Hongru Wang , Deng Cai , Wanjun Zhong , Shijue Huang , Jeff Z. Pan , Zeming Liu , Kam-Fai Wong

Large Reasoning Models (LRMs) have introduced a new paradigm in AI by enabling models to ``think before responding" via chain-of-thought reasoning. However, the absence of open and reproducible recipes for building reasoning-centric medical…

Computer Vision and Pattern Recognition · Computer Science 2026-02-19 Xiaoke Huang , Juncheng Wu , Hui Liu , Xianfeng Tang , Yuyin Zhou

Doctors and patients alike increasingly use Large Language Models (LLMs) to diagnose clinical cases. However, unlike domains such as math or coding, where correctness can be objectively defined by the final answer, medical diagnosis…

Computation and Language · Computer Science 2025-05-21 Kevin Wu , Eric Wu , Rahul Thapa , Kevin Wei , Angela Zhang , Arvind Suresh , Jacqueline J. Tao , Min Woo Sun , Alejandro Lozano , James Zou

Reinforcement learning (RL) has emerged as a powerful approach for tackling complex medical decision-making problems such as treatment planning, personalized medicine, and optimizing the scheduling of surgeries and appointments. It has…

Computation and Language · Computer Science 2023-10-31 Ying Liu , Haozhu Wang , Huixue Zhou , Mingchen Li , Yu Hou , Sicheng Zhou , Fang Wang , Rama Hoetzlein , Rui Zhang

Large reasoning models excel in domains like mathematics where intermediate reasoning is straightforward to verify, but struggle to self-correct in medicine fields where evaluating intermediate reasoning is cumbersome and expensive. This…

Artificial Intelligence · Computer Science 2026-02-26 Zongxian Yang , Jiayu Qian , Zegao Peng , Haoyu Zhang , Yu-An Huang , KC Tan , Zhi-An Huang

Integrating large language models (LLMs) like DeepSeek R1 into healthcare requires rigorous evaluation of their reasoning alignment with clinical expertise. This study assesses DeepSeek R1's medical reasoning against expert patterns using…

Computation and Language · Computer Science 2025-04-02 Birger Moell , Fredrik Sand Aronsson , Sanian Akbar

Large language models (LLMs) have achieved strong performance on medical exam-style tasks, motivating growing interest in their deployment in real-world clinical settings. However, clinical decision-making is inherently safety-critical,…

Computation and Language · Computer Science 2026-04-13 Xiaohan Ren , Chenxiao Fan , Wenyin Ma , Hongliang He , Chongming Gao , Xiaoyan Zhao , Fuli Feng

Large language models are increasingly used for complex reasoning tasks where high-quality offline data such as expert-annotated solutions and distilled reasoning traces are often available. However, in environments with sparse rewards,…

Artificial Intelligence · Computer Science 2025-08-11 Yihao Liu , Shuocheng Li , Lang Cao , Yuhang Xie , Mengyu Zhou , Haoyu Dong , Xiaojun Ma , Shi Han , Dongmei Zhang

Reasoning has substantially improved the performance of large language models (LLMs) on complicated tasks. Central to the current reasoning studies, Process Reward Models (PRMs) offer a fine-grained evaluation of intermediate reasoning…

Machine Learning · Computer Science 2025-11-05 Qi Cao , Ruiyi Wang , Ruiyi Zhang , Sai Ashish Somayajula , Pengtao Xie

Efficiently acquiring external knowledge and up-to-date information is essential for effective reasoning and text generation in large language models (LLMs). Prompting advanced LLMs with reasoning capabilities to use search engines during…

Computation and Language · Computer Science 2025-08-07 Bowen Jin , Hansi Zeng , Zhenrui Yue , Jinsung Yoon , Sercan Arik , Dong Wang , Hamed Zamani , Jiawei Han

Large Language Models (LLMs) have demonstrated significant potential in medical Question Answering (QA), yet they remain prone to hallucinations and ungrounded reasoning, limiting their reliability in high-stakes clinical scenarios. While…

Information Retrieval · Computer Science 2026-01-09 Jessica Ryan , Alexander I. Gumilang , Robert Wiliam , Derwin Suhartono

Existing Large Reasoning Models (LRMs) have shown the potential of reinforcement learning (RL) to enhance the complex reasoning capabilities of Large Language Models~(LLMs). While they achieve remarkable performance on challenging tasks…

Artificial Intelligence · Computer Science 2025-03-19 Huatong Song , Jinhao Jiang , Yingqian Min , Jie Chen , Zhipeng Chen , Wayne Xin Zhao , Lei Fang , Ji-Rong Wen

Although large language models (LLMs) have demonstrated impressive reasoning capabilities across general domains, their effectiveness in real-world clinical practice remains limited. This is likely due to their insufficient exposure to…