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In medical scenarios, effectively retrieving external knowledge and leveraging it for rigorous logical reasoning is of significant importance. Despite their potential, existing work has predominantly focused on enhancing either retrieval or…

Computation and Language · Computer Science 2026-01-21 Keer Lu , Zheng Liang , Youquan Li , Jiejun Tan , Xili Wang , Da Pan , Shusen Zhang , Guosheng Dong , Bin Cui , Yunhuai Liu , Wentao Zhang

Medical language models face critical barriers to real-world clinical reasoning applications. However, mainstream efforts, which fall short in task coverage, lack fine-grained supervision for intermediate reasoning steps, and rely on…

Computation and Language · Computer Science 2025-11-26 Shuyang Jiang , Yusheng Liao , Zhe Chen , Ya Zhang , Yanfeng Wang , Yu Wang

Vision-language models (VLMs) have achieved impressive progress in natural image reasoning, yet their potential in medical imaging remains underexplored. Medical vision-language tasks demand precise understanding and clinically coherent…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Yuxiang Lai , Jike Zhong , Ming Li , Shitian Zhao , Yuheng Li , Konstantinos Psounis , Xiaofeng Yang

Accurate clinical diagnosis requires extensive domain knowledge and complex clinical reasoning capabilities. Although large language models (LLMs) hold great potential for clinical reasoning, their high computational and memory requirements…

Computers and Society · Computer Science 2026-05-12 Xinchun Su , Chunxu Luo , Lipeng Ma , Yixuan Li , Weidong Yang

The application of Vision-Language Models (VLMs) in medicine is critically hampered by the scarcity of high-quality, expert-annotated data. Supervised Fine-Tuning (SFT) on existing datasets often leads to poor generalization on unseen…

Machine Learning · Computer Science 2025-12-09 Weihai Zhi , Jiayan Guo , Shangyang Li

Medical Vision-Language Models (MedVLMs) excel at perception tasks but struggle with complex clinical reasoning required in real-world scenarios. While reinforcement learning (RL) has been explored to enhance reasoning capabilities,…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Meidan Ding , Jipeng Zhang , Wenxuan Wang , Haiqin Zhong , Xiaoling Luo , Wenting Chen , Linlin Shen

Machine learning (ML) holds great promise for clinical applications but is often hindered by limited access to high-quality data due to privacy concerns, high costs, and long timelines associated with clinical trials. While large language…

Computation and Language · Computer Science 2026-03-27 Zerui Xu , Fang Wu , Yingzhou Lu , Yuanyuan Zhang , Yue Zhao

Reinforcement learning from verifiable rewards (RLVR) has recently gained attention for its ability to elicit self-evolved reasoning capabilitie from base language models without explicit reasoning supervisions, as demonstrated by…

Computation and Language · Computer Science 2025-02-28 Sheng Zhang , Qianchu Liu , Guanghui Qin , Tristan Naumann , Hoifung Poon

Incentivizing the reasoning ability of Multimodal Large Language Models (MLLMs) is essential for medical applications to transparently analyze medical scans and provide reliable diagnosis. However, existing medical MLLMs rely solely on…

Computer Vision and Pattern Recognition · Computer Science 2025-10-22 Lehan Wang , Yi Qin , Honglong Yang , Xiaomeng Li

Medical problem-solving demands expert knowledge and intricate reasoning. Recent studies of large language models (LLMs) attempt to ease this complexity by introducing external knowledge verification through retrieval-augmented generation…

Computation and Language · Computer Science 2026-01-19 Yue Huang , Yanyuan Chen , Dexuan Xu , Chenzhuo Zhao , Weihua Yue , Yu Huang

Automatic Speech Recognition (ASR) systems are pivotal in transcribing speech into text, yet the errors they introduce can significantly degrade the performance of downstream tasks like summarization. This issue is particularly pronounced…

While large language models show promise in medical applications, achieving expert-level clinical reasoning remains challenging due to the need for both accurate answers and transparent reasoning processes. To address this challenge, we…

Machine Learning · Computer Science 2025-09-22 Chi Liu , Derek Li , Yan Shu , Robin Chen , Derek Duan , Teng Fang , Bryan Dai

In this work, we present our various contributions to the objective of building a decision support tool for the diagnosis of rare diseases. Our goal is to achieve a state of knowledge where the uncertainty about the patient's disease is…

Clinical Decision Support Systems (CDSSs) provide reasoning and inquiry guidance for physicians, yet they face notable challenges, including high maintenance costs and low generalization capability. Recently, Large Language Models (LLMs)…

Computation and Language · Computer Science 2026-04-24 Yue Guo , Fanfu Wang , Jianwei Lv , Xincheng Shi , Yuchen Li , Youya Wang , Yunsheng Zeng , Yujing Liu , Yunhao Qiao , Gen Li , Junfeng Wang , Bo Yuan

Recent advances in medical large language models have explored Test-Time Reinforcement Learning (TTRL) to enhance reasoning. However, standard TTRL often relies on majority voting (MV) as a heuristic supervision signal, which can be…

Machine Learning · Computer Science 2026-03-11 Kailong Fan , Anqi Pu , Yichen Wu , Wanhua Li , Yicong Li , Hanspeter Pfister , Huafeng Liu , Xiang Li , Quanzheng Li , Ning Guo

Interpretation is critical for disease diagnosis, but existing models struggle to balance predictive accuracy with human-understandable rationales. While large language models (LLMs) offer strong reasoning abilities, their clinical use is…

Computation and Language · Computer Science 2025-07-15 Shuai Niu , Jing Ma , Hongzhan Lin , Liang Bai , Zhihua Wang , Yida Xu , Yunya Song , Xian Yang

Recent developments in Large Language Model (LLM)-based agents have shown impressive capabilities spanning multiple domains, exemplified by deep research systems that demonstrate superior performance on complex information-seeking and…

Computation and Language · Computer Science 2025-09-03 Ailing Yu , Lan Yao , Jingnan Liu , Zhe Chen , Jiajun Yin , Yuan Wang , Xinhao Liao , Zhiling Ye , Ji Li , Yun Yue , Hansong Xiao , Hualei Zhou , Chunxiao Guo , Peng Wei , Junwei Liu , Jinjie Gu

Reinforcement Learning (RL) has been shown to significantly boost reasoning capabilities of large language models (LLMs) in math, coding, and multi-hop reasoning tasks. However, RL fine-tuning requires abundant high-quality verifiable data,…

Reinforcement learning (RL) has shown great success in estimating sequential treatment strategies which take into account patient heterogeneity. However, health-outcome information, which is used as the reward for reinforcement learning…

Machine Learning · Computer Science 2021-02-24 Aaron Sonabend-W , Nilanjana Laha , Ashwin N. Ananthakrishnan , Tianxi Cai , Rajarshi Mukherjee

Large Language Models (LLMs) have shown strong potential in complex medical reasoning yet face diminishing gains under inference scaling laws. While existing studies augment LLMs with various knowledge types, it remains unclear how…

Artificial Intelligence · Computer Science 2026-02-10 Yu Zhao , Hao Guan , Yongcheng Jing , Ying Zhang , Dacheng Tao
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