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This paper presents the first deep reinforcement learning (DRL) framework to estimate the optimal Dynamic Treatment Regimes from observational medical data. This framework is more flexible and adaptive for high dimensional action and state…

Artificial Intelligence · Computer Science 2018-01-30 Ning Liu , Ying Liu , Brent Logan , Zhiyuan Xu , Jian Tang , Yanzhi Wang

Proactive Recommender Systems (PRSs) aim to guide user preference shift toward target items by generating paths of intermediate recommendations. Reinforcement learning (RL) provides a principled framework for optimizing such sequential…

Machine Learning · Computer Science 2026-05-29 Hongru Hou , Tiehua Mei , Denghui Geng , Jinhui Huang , Ao Xu , Hengrui Chen , Jiaqing Liang , Deqing Yang

Sequential recommendation methods play a crucial role in modern recommender systems because of their ability to capture a user's dynamic interest from her/his historical interactions. Despite their success, we argue that these approaches…

Information Retrieval · Computer Science 2021-03-02 Xu Xie , Fei Sun , Zhaoyang Liu , Shiwen Wu , Jinyang Gao , Bolin Ding , Bin Cui

Process Reward Models (PRMs) have recently emerged as a powerful framework for supervising intermediate reasoning steps in large language models (LLMs). Previous PRMs are primarily trained on model final output responses and struggle to…

Computation and Language · Computer Science 2025-09-26 Jiaru Zou , Ling Yang , Jingwen Gu , Jiahao Qiu , Ke Shen , Jingrui He , Mengdi Wang

Offline preference-based reinforcement learning (PbRL) mitigates the need for reward definition, aligning with human preferences via preference-driven reward feedback without interacting with the environment. However, trajectory-wise…

Machine Learning · Computer Science 2025-09-25 Teng Pang , Bingzheng Wang , Guoqiang Wu , Yilong Yin

Sepsis is a leading cause of mortality and its treatment is very expensive. Sepsis treatment is also very challenging because there is no consensus on what interventions work best and different patients respond very differently to the same…

Machine Learning · Computer Science 2022-03-29 Pramod Kaushik , Sneha Kummetha , Perusha Moodley , Raju S. Bapi

Conversational Recommender Systems (CRS) actively elicit user preferences to generate adaptive recommendations. Mainstream reinforcement learning-based CRS solutions heavily rely on handcrafted reward functions, which may not be aligned…

Information Retrieval · Computer Science 2023-11-01 Zhendong Chu , Nan Wang , Hongning Wang

As a robot's operational environment and tasks to perform within it grow in complexity, the explicit specification and balancing of optimization objectives to achieve a preferred behavior profile moves increasingly farther out of reach.…

Robotics · Computer Science 2026-03-10 Yi-Shiuan Tung , Gyanig Kumar , Wei Jiang , Bradley Hayes , Alessandro Roncone

Dynamic treatment regimes operationalize the clinical decision process as a sequence of functions, one for each clinical decision, where each function takes as input up-to-date patient information and gives as output a single recommended…

Methodology · Statistics 2012-08-08 Eric B. Laber , Daniel J. Lizotte , Bradley Ferguson

Current advances in recommender systems have been remarkably successful in optimizing immediate engagement. However, long-term user engagement, a more desirable performance metric, remains difficult to improve. Meanwhile, recent…

Information Retrieval · Computer Science 2023-06-05 Wanqi Xue , Qingpeng Cai , Zhenghai Xue , Shuo Sun , Shuchang Liu , Dong Zheng , Peng Jiang , Kun Gai , Bo An

Understanding the severity of conditions shown in images in medical diagnosis is crucial, serving as a key guide for clinical assessment, treatment, as well as evaluating longitudinal progression. This paper proposes Con- PrO: a novel…

Computer Vision and Pattern Recognition · Computer Science 2024-04-30 Hong Nguyen , Hoang Nguyen , Melinda Chang , Hieu Pham , Shrikanth Narayanan , Michael Pazzani

This thesis develops theoretical frameworks and algorithms that advance constrained reinforcement learning (RL) across control, preference learning, and alignment of large language models. The first contribution addresses constrained Markov…

Machine Learning · Computer Science 2025-12-12 Akhil Agnihotri

The pursuit of energy-efficient and adaptive artificial intelligence (AI) has positioned neuromorphic computing as a promising alternative to conventional computing. However, achieving learning on these platforms requires techniques that…

Machine Learning · Computer Science 2026-01-27 Jesús García Fernández , Nasir Ahmad , Marcel van Gerven

Conveying complex objectives to reinforcement learning (RL) agents often requires meticulous reward engineering. Preference-based RL methods are able to learn a more flexible reward model based on human preferences by actively incorporating…

Machine Learning · Computer Science 2022-05-26 Xinran Liang , Katherine Shu , Kimin Lee , Pieter Abbeel

Sepsis is a potentially life threatening inflammatory response to infection or severe tissue damage. It has a highly variable clinical course, requiring constant monitoring of the patient's state to guide the management of intravenous…

Machine Learning · Computer Science 2022-02-21 Thesath Nanayakkara , Gilles Clermont , Christopher James Langmead , David Swigon

Reinforcement Learning from Human Feedback (RLHF) has emerged as a popular paradigm for aligning models with human intent. Typically RLHF algorithms operate in two phases: first, use human preferences to learn a reward function and second,…

Machine Learning · Computer Science 2024-05-01 Joey Hejna , Rafael Rafailov , Harshit Sikchi , Chelsea Finn , Scott Niekum , W. Bradley Knox , Dorsa Sadigh

Our goal is to accurately and efficiently learn reward functions for autonomous robots. Current approaches to this problem include inverse reinforcement learning (IRL), which uses expert demonstrations, and preference-based learning, which…

Robotics · Computer Science 2019-06-24 Malayandi Palan , Nicholas C. Landolfi , Gleb Shevchuk , Dorsa Sadigh

Controlled automated story generation seeks to generate natural language stories satisfying constraints from natural language critiques or preferences. Existing methods to control for story preference utilize prompt engineering which is…

Computation and Language · Computer Science 2022-12-16 Louis Castricato , Alexander Havrilla , Shahbuland Matiana , Michael Pieler , Anbang Ye , Ian Yang , Spencer Frazier , Mark Riedl

Increasing the success rate of a process, i.e. the percentage of cases that end in a positive outcome, is a recurrent process improvement goal. At runtime, there are often certain actions (a.k.a. treatments) that workers may execute to lift…

Machine Learning · Computer Science 2023-03-08 Zahra Dasht Bozorgi , Marlon Dumas , Marcello La Rosa , Artem Polyvyanyy , Mahmoud Shoush , Irene Teinemaa

Inpatient clinical reasoning is a sequential decision under partial observability: the clinician sees the admission so far and must choose the next action whose downstream consequences are not yet visible. Existing clinical-LLM evaluations…

Computation and Language · Computer Science 2026-05-12 Aishik Nagar , Arun-Kumar Kaliya-Perumal , Yu-Hsuan Han , Andrew Sheng-Han Huang , Kristen Kee , Yushi Cao , Yiming Chen , Hongchao Jiang