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Large Language Models (LLMs) have emerged as a potential solution to assist digital health development with patient education, commonly medication-related enquires. We trained and validated Med-Pal, a medication domain-specific LLM-chatbot…

Real-world health questions from patients often unintentionally embed false assumptions or premises. In such cases, safe medical communication typically involves redirection: addressing the implicit misconception and then responding to the…

Computation and Language · Computer Science 2026-04-21 Sraavya Sambara , Yuan Pu , Ayman Ali , Vishala Mishra , Lionel Wong , Monica Agrawal

While Large Language Models (LLMs) demonstrate significant potential in providing accessible mental health support, their practical deployment raises critical trustworthiness concerns due to the domains high-stakes and safety-sensitive…

Computation and Language · Computer Science 2026-03-04 Zixin Xiong , Ziteng Wang , Haotian Fan , Xinjie Zhang , Wenxuan Wang

Evidence to guide healthcare decisions is often limited by a lack of relevant and trustworthy literature as well as difficulty in contextualizing existing research for a specific patient. Large language models (LLMs) could potentially…

Recently, Large Language Models (LLMs) have gained significant traction in medical domain, especially in developing a QA systems to Medical QA systems for enhancing access to healthcare in low-resourced settings. This paper compares five…

Computation and Language · Computer Science 2026-02-17 Shefayat E Shams Adib , Ahmed Alfey Sani , Ekramul Alam Esham , Ajwad Abrar , Tareque Mohmud Chowdhury

Large language models (LLMs) show promise for supporting clinical decision-making in complex fields such as rheumatology. Our evaluation shows that smaller language models (SLMs), combined with retrieval-augmented generation (RAG), achieve…

Computation and Language · Computer Science 2025-07-11 Sabine Felde , Rüdiger Buchkremer , Gamal Chehab , Christian Thielscher , Jörg HW Distler , Matthias Schneider , Jutta G. Richter

Large Language Models (LLMs) promise to streamline software code reviews, but their ability to produce consistent assessments remains an open question. In this study, we tested four leading LLMs -- GPT-4o mini, GPT-4o, Claude 3.5 Sonnet,…

Software Engineering · Computer Science 2025-03-03 Eugene Klishevich , Yegor Denisov-Blanch , Simon Obstbaum , Igor Ciobanu , Michal Kosinski

The integration of Large Language Models (LLMs) into healthcare settings has gained significant attention, particularly for question-answering tasks. Given the high-stakes nature of healthcare, it is essential to ensure that LLM-generated…

Retrieval-augmented generation (RAG) has emerged as a promising approach to enhance the performance of large language models (LLMs) in knowledge-intensive tasks such as those from medical domain. However, the sensitive nature of the medical…

Computation and Language · Computer Science 2024-11-15 Nghia Trung Ngo , Chien Van Nguyen , Franck Dernoncourt , Thien Huu Nguyen

Large language models (LLMs) are entering clinical workflows as decision support tools, yet how they respond to explicit patient value statements -- the core content of shared decision-making -- remains unmeasured. We conducted a factorial…

Computers and Society · Computer Science 2026-03-03 Sanjay Basu

With the proliferation of Large Language Models (LLMs) in diverse domains, there is a particular need for unified evaluation standards in clinical medical scenarios, where models need to be examined very thoroughly. We present CliMedBench,…

Computation and Language · Computer Science 2024-10-07 Zetian Ouyang , Yishuai Qiu , Linlin Wang , Gerard de Melo , Ya Zhang , Yanfeng Wang , Liang He

As Large Language Models (LLMs) become increasingly integrated into high-stakes domains, there have been several approaches proposed toward generating natural language explanations. These explanations are crucial for enhancing the…

Computation and Language · Computer Science 2025-11-13 Krithi Shailya , Shreya Rajpal , Gokul S Krishnan , Balaraman Ravindran

As Large Language Models (LLMs) become widely accessible, a detailed understanding of their knowledge within specific domains becomes necessary for successful real world use. This is particularly critical in the domains of medicine and…

Large language models (LLMs) have made rapid improvement on medical benchmarks, but their unreliability remains a persistent challenge for safe real-world uses. To design for the use LLMs as a category, rather than for specific models,…

Computation and Language · Computer Science 2024-10-14 Andrew M. Bean , Karolina Korgul , Felix Krones , Robert McCraith , Adam Mahdi

The development of open-source, multilingual medical language models can benefit a wide, linguistically diverse audience from different regions. To promote this domain, we present contributions from the following: First, we construct a…

Computation and Language · Computer Science 2024-06-04 Pengcheng Qiu , Chaoyi Wu , Xiaoman Zhang , Weixiong Lin , Haicheng Wang , Ya Zhang , Yanfeng Wang , Weidi Xie

High-performing medical Large Language Models (LLMs) typically require extensive fine-tuning with substantial computational resources, limiting accessibility for resource-constrained healthcare institutions. This study introduces a…

Computation and Language · Computer Science 2025-10-17 Ziad Elshaer , Essam A. Rashed

Large language models (LLMs) are increasingly evaluated in clinical settings using multi-dimensional rubrics which quantify reasoning quality, safety, and patient-centeredness. Yet, replicating specific mistakes in other LLM models is not…

Computation and Language · Computer Science 2026-04-08 Oleksii Proniakin , Diego Fajardo , Ruslan Nazarenko , Razvan Marinescu

Advances in Large Language Models (LLMs) have led to significant interest in their potential to support human experts across a range of domains, including public health. In this work we present automated evaluations of LLMs for public…

While Large Language Models (LLMs) excel on standardized medical exams, high scores often fail to translate to high-quality responses for real-world medical queries. Current evaluations rely heavily on multiple-choice questions, failing to…

Large language models (LLMs) have demonstrated potential applications in medicine, yet data privacy and computational burden limit their deployment in healthcare institutions. Open-source and lightweight versions of LLMs emerge as potential…

Machine Learning · Computer Science 2024-07-24 Qiuhong Wei , Ying Cui , Mengwei Ding , Yanqin Wang , Lingling Xiang , Zhengxiong Yao , Ceran Chen , Ying Long , Zhezhen Jin , Ximing Xu