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Proteins perform critical processes in all living systems: converting solar energy into chemical energy, replicating DNA, as the basis of highly performant materials, sensing and much more. While an incredible range of functionality has…

Biomolecules · Quantitative Biology 2021-09-29 Leonardo V. Castorina , Rokas Petrenas , Kartic Subr , Christopher W. Wood

Graph Neural Networks (GNNs) benchmarks often report single point estimates, even when performance differences are small relative to variation across random seeds, train/test splits, and datasets. Confidence intervals, paired comparisons,…

Computational Engineering, Finance, and Science · Computer Science 2026-05-12 Kleyton da Costa , Bernardo Modenesi

Differentially private (DP) image synthesis aims to generate artificial images that retain the properties of sensitive images while protecting the privacy of individual images within the dataset. Despite recent advancements, we find that…

Cryptography and Security · Computer Science 2025-09-01 Chen Gong , Kecen Li , Zinan Lin , Tianhao Wang

Deep learning holds immense promise for spectroscopy, yet research and evaluation in this emerging field often lack standardized formulations. To address this issue, we introduce SpectrumLab, a pioneering unified platform designed to…

The widespread application of Artificial Intelligence (AI) techniques has significantly influenced the development of new therapeutic agents. These computational methods can be used to design and predict the properties of generated…

Neural and Evolutionary Computing · Computer Science 2024-08-21 Arthur Cerveira , Frederico Kremer , Darling de Andrade Lourenço , Ulisses B Corrêa

Model merging provides a scalable alternative to multi-task training by combining specialized finetuned models through parameter arithmetic, enabling efficient deployment without the need for joint training or access to all task data. While…

Machine Learning · Computer Science 2025-10-21 Yifei He , Siqi Zeng , Yuzheng Hu , Rui Yang , Tong Zhang , Han Zhao

The growing demand for data-driven decision-making has created an urgent need for data agents that can integrate structured and unstructured data for analysis. While data agents show promise for enabling users to perform complex analytics…

Databases · Computer Science 2025-09-03 Ziting Wang , Shize Zhang , Haitao Yuan , Jinwei Zhu , Shifu Li , Wei Dong , Gao Cong

A key step in medical diagnosis is giving the patient a universally recognized label (e.g. Appendicitis) which essentially assigns the patient to a class(es) of patients with similar body failures. However, two patients having the same…

Artificial Intelligence · Computer Science 2019-09-10 Moshe BenBassat

Today's Internet Services are undergoing fundamental changes and shifting to an intelligent computing era where AI is widely employed to augment services. In this context, many innovative AI algorithms, systems, and architectures are…

Obtaining standardized crowdsourced benchmark of computational methods is a major issue in data science communities. Dedicated frameworks enabling fair benchmarking in a unified environment are yet to be developed. Here we introduce…

Machine Learning · Computer Science 2022-06-28 Zhen Xu , Sergio Escalera , Isabelle Guyon , Adrien Pavão , Magali Richard , Wei-Wei Tu , Quanming Yao , Huan Zhao

Publicly accessible benchmarks that allow for assessing and comparing model performances are important drivers of progress in artificial intelligence (AI). While recent advances in AI capabilities hold the potential to transform medical…

Artificial Intelligence · Computer Science 2022-12-26 Kathrin Blagec , Jakob Kraiger , Wolfgang Frühwirt , Matthias Samwald

Deep learning has advanced mass spectrometry data interpretation, yet most models remain feature extractors rather than unified scoring frameworks. We present pUniFind, the first large-scale multimodal pre-trained model in proteomics that…

While machine learning has witnessed significant advancements, the emphasis has largely been on data acquisition and model creation. However, achieving a comprehensive assessment of machine learning solutions in real-world settings…

Benefiting from high-quality datasets and standardized evaluation metrics, machine learning (ML) has achieved sustained progress and widespread applications. However, while applying machine learning to relational databases (RDBs), the…

Machine Learning · Computer Science 2023-10-31 Zizhao Zhang , Yi Yang , Lutong Zou , He Wen , Tao Feng , Jiaxuan You

Deep learning and large public datasets have recently catalyzed the proliferation of AI models for processing brain recordings. However, systematically evaluating these models remains a challenge: not only do the preprocessing pipelines,…

The performance of machine learning models in drug discovery is highly dependent on the quality and consistency of the underlying training data. Due to limitations in dataset sizes, many models are trained by aggregating bioactivity data…

Machine Learning · Computer Science 2025-11-21 Vincent Fan , Regina Barzilay

Artificial intelligence-based systems for player risk detection have become central to harm prevention efforts in the gambling industry. However, growing concerns around transparency and effectiveness have highlighted the absence of…

Large Language Models (LLMs) have demonstrated remarkable capabilities on general text; however, their proficiency in specialized scientific domains that require deep, interconnected knowledge remains largely uncharacterized. Metabolomics…

Computation and Language · Computer Science 2025-10-17 Yuxing Lu , Xukai Zhao , J. Ben Tamo , Micky C. Nnamdi , Rui Peng , Shuang Zeng , Xingyu Hu , Jinzhuo Wang , May D. Wang

Existing biomedical benchmarks do not provide end-to-end infrastructure for training, evaluation, and inference of models that integrate multimodal biological data and a broad range of machine learning tasks in therapeutics. We present…

Machine Learning · Computer Science 2026-01-23 Alejandro Velez-Arce , Jesus Caraballo , Marinka Zitnik
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