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There are two main barriers to using large language models (LLMs) in clinical reasoning. Firstly, while LLMs exhibit significant promise in Natural Language Processing (NLP) tasks, their performance in complex reasoning and planning falls…

Artificial Intelligence · Computer Science 2024-12-31 Shengxin Hong , Liang Xiao , Xin Zhang , Jianxia Chen

Retrieval-augmented generation (RAG) has become a widely adopted paradigm for enabling knowledge-grounded large language models (LLMs). However, standard RAG pipelines often fail to ensure that model reasoning remains consistent with the…

Artificial Intelligence · Computer Science 2025-10-14 Jiaqi Wei , Hao Zhou , Xiang Zhang , Di Zhang , Zijie Qiu , Wei Wei , Jinzhe Li , Wanli Ouyang , Siqi Sun

This paper presents CaseGPT, an innovative approach that combines Large Language Models (LLMs) and Retrieval-Augmented Generation (RAG) technology to enhance case-based reasoning in the healthcare and legal sectors. The system addresses the…

Information Retrieval · Computer Science 2024-07-12 Rui Yang

Multimodal Large Language Models (MLLMs) have significantly advanced AI-assisted medical diagnosis, but they often generate factually inconsistent responses that deviate from established medical knowledge. Retrieval-Augmented Generation…

Computer Vision and Pattern Recognition · Computer Science 2025-07-11 Jinhong Wang , Tajamul Ashraf , Zongyan Han , Jorma Laaksonen , Rao Mohammad Anwer

The adoption of large language models (LLMs) in healthcare has attracted significant research interest. However, their performance in healthcare remains under-investigated and potentially limited, due to i) they lack rich domain-specific…

Artificial Intelligence · Computer Science 2024-05-21 Zishan Gu , Fenglin Liu , Changchang Yin , Ping Zhang

Large language models (LLMs) have shown great promise in machine translation, but they still struggle with contextually dependent terms, such as new or domain-specific words. This leads to inconsistencies and errors that are difficult to…

Computation and Language · Computer Science 2024-10-29 Meiqi Chen , Fandong Meng , Yingxue Zhang , Yan Zhang , Jie Zhou

Retrieval-Augmented Generation systems are essential for providing fact-based guidance from Malaysian Clinical Practice Guidelines. However, their effectiveness with image-based queries is limited, as general Vision-Language Model captions…

Computation and Language · Computer Science 2025-11-10 Lee Qi Zun , Mohamad Zulhilmi Bin Abdul Halim , Goh Man Fye

Retrieval-Augmented Generation (RAG) has emerged as a powerful technique for enhancing the quality of responses in Question-Answering (QA) tasks. However, existing approaches often struggle with retrieving contextually relevant information,…

Computation and Language · Computer Science 2026-01-27 Tianyi Yang , Nashrah Haque , Vaishnave Jonnalagadda , Yuya Jeremy Ong , Zhehui Chen , Yanzhao Wu , Lei Yu , Divyesh Jadav , Wenqi Wei

We propose a simple, unsupervised method that injects pragmatic principles in retrieval-augmented generation (RAG) frameworks such as Dense Passage Retrieval to enhance the utility of retrieved contexts. Our approach first identifies which…

Computation and Language · Computer Science 2025-02-28 Haris Riaz , Ellen Riloff , Mihai Surdeanu

Retrieval augmented generation (RAG), while effectively integrating external knowledge to address the inherent limitations of large language models (LLMs), can be hindered by imperfect retrieval that contain irrelevant, misleading, or even…

Computation and Language · Computer Science 2025-06-03 Fei Wang , Xingchen Wan , Ruoxi Sun , Jiefeng Chen , Sercan Ö. Arık

Retrieval Augmented Generation (RAG) is a technique used to augment Large Language Models (LLMs) with contextually relevant, time-critical, or domain-specific information without altering the underlying model parameters. However,…

Information Retrieval · Computer Science 2024-08-20 Laurent Mombaerts , Terry Ding , Adi Banerjee , Florian Felice , Jonathan Taws , Tarik Borogovac

Retrieval-Augmented Generation (RAG) systems enhance response credibility and traceability by displaying reference contexts, but this transparency simultaneously introduces a novel black-box attack vector. Existing document poisoning…

Computation and Language · Computer Science 2026-01-27 Runqi Sui

Predicting future clinical outcomes from electronic health records (EHR) remains challenging due to the complexity and heterogeneity of patient data. LLMs have shown strong potential for such predictive tasks, yet existing approaches mainly…

Computation and Language · Computer Science 2026-05-05 Yushi Cao , Yiming Chen , Hongchao Jiang , Hung-yi Lee , Robby T. Tan

While state-of-the-art language models have achieved impressive results, they remain susceptible to inference-time adversarial attacks, such as adversarial prompts generated by red teams arXiv:2209.07858. One approach proposed to improve…

Computation and Language · Computer Science 2024-01-12 Steffi Chern , Zhen Fan , Andy Liu

Retrieval-Augmented Generation (RAG) systems often face limitations in specialized domains such as fintech, where domain-specific ontologies, dense terminology, and acronyms complicate effective retrieval and synthesis. This paper…

Artificial Intelligence · Computer Science 2025-10-30 Thomas Cook , Richard Osuagwu , Liman Tsatiashvili , Vrynsia Vrynsia , Koustav Ghosal , Maraim Masoud , Riccardo Mattivi

Accurate healthcare prediction is critical for improving patient outcomes and reducing operational costs. Bolstered by growing reasoning capabilities, large language models (LLMs) offer a promising path to enhance healthcare predictions by…

Artificial Intelligence · Computer Science 2025-11-18 Chuang Zhao , Hui Tang , Hongke Zhao , Xiaofang Zhou , Xiaomeng Li

Large language models (LLMs) have shown promise in medical domains, but their ability to handle specialized neurological reasoning requires systematic evaluation. We developed a comprehensive benchmark using 305 questions from Israeli Board…

Information Retrieval · Computer Science 2025-08-21 Moran Sorka , Alon Gorenshtein , Dvir Aran , Shahar Shelly

Large language models equipped with retrieval-augmented generation (RAG) represent a burgeoning field aimed at enhancing answering capabilities by leveraging external knowledge bases. Although the application of RAG with language-only…

Computer Vision and Pattern Recognition · Computer Science 2024-06-03 Cheng Tan , Jingxuan Wei , Linzhuang Sun , Zhangyang Gao , Siyuan Li , Bihui Yu , Ruifeng Guo , Stan Z. Li

Dermatological care via telemedicine often lacks the rich context of in-person visits. Clinicians must make diagnoses based on a handful of images and brief descriptions, without the benefit of physical exams, second opinions, or reference…

Artificial Intelligence · Computer Science 2025-08-27 Karishma Thakrar , Shreyas Basavatia , Akshay Daftardar

Retrieval-Augmented Generation (RAG) enhances Large Language Models (LLMs) by incorporating external, domain-specific data into the generative process. While LLMs are highly capable, they often rely on static, pre-trained datasets, limiting…

Artificial Intelligence · Computer Science 2024-12-10 Aniruddha Salve , Saba Attar , Mahesh Deshmukh , Sayali Shivpuje , Arnab Mitra Utsab