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Related papers: SIMPLER: H&E-Informed Representation Learning for …

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Transformer-based models, capable of learning better global dependencies, have recently demonstrated exceptional representation learning capabilities in computer vision and medical image analysis. Transformer reformats the image into…

Histological staining of tissue biopsies, especially hematoxylin and eosin (H&E) staining, serves as the benchmark for disease diagnosis and comprehensive clinical assessment of tissue. However, the process is laborious and time-consuming,…

The self-supervised Masked Image Modeling (MIM) schema, following "mask-and-reconstruct" pipeline of recovering contents from masked image, has recently captured the increasing interest in the multimedia community, owing to the excellent…

Computer Vision and Pattern Recognition · Computer Science 2022-04-19 Hao Liu , Xinghua Jiang , Xin Li , Antai Guo , Deqiang Jiang , Bo Ren

Self-supervised learning (SSL) with Vision Transformers (ViT) has shown immense potential in medical image analysis. However, the quadratic complexity ($\mathcal{O}(N^2)$) of standard self-attention poses a severe barrier for…

Computer Vision and Pattern Recognition · Computer Science 2026-01-26 Hung Q. Vo , Pengyu Yuan , Zheng Yin , Kelvin K. Wong , Chika F. Ezeana , Son T. Ly , Hien V. Nguyen , Stephen T. C. Wong

Pathology foundation models learn morphological representations through self-supervised pretraining on large-scale whole-slide images, yet they do not explicitly capture the underlying molecular state of the tissue. Spatial transcriptomics…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Minsoo Lee , Jonghyun Kim , Juseung Yun , Sunwoo Yu , Jongseong Jang

Due to its superior efficiency in utilizing annotations and addressing gigapixel-sized images, multiple instance learning (MIL) has shown great promise as a framework for whole slide image (WSI) classification in digital pathology…

Quantitative Methods · Quantitative Biology 2023-07-14 Qiehe Sun , Jiawen Li , Jin Xu , Junru Cheng , Tian Guan , Yonghong He

Implicit Neural Representations (INRs) have recently advanced the field of deep learning due to their ability to learn continuous representations of signals without the need for large training datasets. Although INR methods have been…

Image and Video Processing · Electrical Eng. & Systems 2024-09-04 Mevan Ekanayake , Zhifeng Chen , Gary Egan , Mehrtash Harandi , Zhaolin Chen

The popular use of histopathology images, such as hematoxylin and eosin (H&E), has proven to be useful in detecting tumors. However, moving such cancer cases forward for treatment requires accurate on the amount of the human epidermal…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Olaide N. Oyelade , Oliver Hoxey , Yulia Humrye

Structured Illumination Microscopy (SIM) is an imaging technique for achieving both super-resolution (SR) and optical sectioning (OS) in wide-field microscopy. It consists in illuminating the sample with periodic patterns at different…

Recently, deep neural networks have greatly advanced histopathology image segmentation but usually require abundant annotated data. However, due to the gigapixel scale of whole slide images and pathologists' heavy daily workload, obtaining…

Computer Vision and Pattern Recognition · Computer Science 2023-03-13 Wentao Pan , Jiangpeng Yan , Hanbo Chen , Jiawei Yang , Zhe Xu , Xiu Li , Jianhua Yao

Masked Image Modeling (MIM) techniques have redefined the landscape of computer vision, enabling pre-trained models to achieve exceptional performance across a broad spectrum of tasks. Despite their success, the full potential of MIM-based…

Computer Vision and Pattern Recognition · Computer Science 2024-09-05 Sumin Son , Hyesong Choi , Dongbo Min

A central problem in neuroscience is reconstructing neuronal circuits on the synapse level. Due to a wide range of scales in brain architecture such reconstruction requires imaging that is both high-resolution and high-throughput. Existing…

Computer Vision and Pattern Recognition · Computer Science 2012-10-03 Tao Hu , Juan Nunez-Iglesias , Shiv Vitaladevuni , Lou Scheffer , Shan Xu , Mehdi Bolorizadeh , Harald Hess , Richard Fetter , Dmitri Chklovskii

The revolutionary technology of \emph{Stacked Intelligent Metasurfaces (SIM)} has been recently shown to be capable of carrying out advanced signal processing directly in the native electromagnetic (EM) wave domain. An SIM is fabricated by…

Information Theory · Computer Science 2023-05-16 Jiancheng An , Chao Xu , Derrick Wing Kwan Ng , George C. Alexandropoulos , Chongwen Huang , Chau Yuen , Lajos Hanzo

We propose a Deep learning-based weak label learning method for analyzing whole slide images (WSIs) of Hematoxylin and Eosin (H&E) stained tumor tissue not requiring pixel-level or tile-level annotations using Self-supervised pre-training…

Image and Video Processing · Electrical Eng. & Systems 2023-06-29 Yoni Schirris , Efstratios Gavves , Iris Nederlof , Hugo Mark Horlings , Jonas Teuwen

Integrating domain knowledge into deep learning has emerged as a promising direction for improving model interpretability, generalization, and data efficiency. In this work, we present a novel knowledge-guided ViT-based Masked Autoencoder…

Machine Learning · Computer Science 2026-02-11 Abdul Matin , Rupasree Dey , Tanjim Bin Faruk , Shrideep Pallickara , Sangmi Lee Pallickara

Stacked intelligent metasurfaces (SIM) represents an advanced signal processing paradigm that enables over-the-air processing of electromagnetic waves at the speed of light. Its multi-layer structure exhibits customizable increased…

Signal Processing · Electrical Eng. & Systems 2024-02-15 Hao Liu , Jiancheng An , Derrick Wing Kwan Ng , George C. Alexandropoulos , Lu Gan

With the development of medical imaging technology and machine learning, computer-assisted diagnosis which can provide impressive reference to pathologists, attracts extensive research interests. The exponential growth of medical images and…

Computer Vision and Pattern Recognition · Computer Science 2020-10-08 Xiao Kang , Xingbo Liu , Xiushan Nie , Yilong Yin

Universal, transferable whole-slide image (WSI) representations are central to computational pathology. Incorporating multiple markers (e.g., immunohistochemistry, IHC) alongside H&E enriches H&E-based features with diverse, biologically…

Computer Vision and Pattern Recognition · Computer Science 2025-12-04 Yizhi Zhang , Lei Fan , Zhulin Tao , Donglin Di , Yang Song , Sidong Liu , Cong Cong

Radiological images such as computed tomography (CT) and X-rays render anatomy with intrinsic structures. Being able to reliably locate the same anatomical structure across varying images is a fundamental task in medical image analysis. In…

Computer Vision and Pattern Recognition · Computer Science 2023-10-24 Ke Yan , Jinzheng Cai , Dakai Jin , Shun Miao , Dazhou Guo , Adam P. Harrison , Youbao Tang , Jing Xiao , Jingjing Lu , Le Lu

Incremental Learning (IL) aims to learn new tasks while preserving previously acquired knowledge. Integrating the zero-shot learning capabilities of pre-trained vision-language models into IL methods has marked a significant advancement.…

Computer Vision and Pattern Recognition · Computer Science 2026-03-20 Haihua Luo , Xuming Ran , Jiangrong Shen , Timo Hämäläinen , Zhonghua Chen , Qi Xu , Fengyu Cong
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