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Purpose: Measuring the ortho-positronium (oPs) lifetime in human tissue bears the potential of adding clinically relevant information about the tissue microenvironment to conventional positron emission tomography (PET). Through phantom…

In living organisms the positron-electron annihilation (occurring during the PET imaging) proceeds in about 30% via creation of a metastable ortho-positronium atom. In the tissue, due to the pick-off and conversion processes, over 98% of…

Positronium imaging was recently proposed to image the properties of positronium atoms in the patient body. Positronium properties depend on the size of intramolecular voids and oxygen concentration; therefore, they deliver information…

Positronium-based imaging requires realistic modelling of positronium (Ps) decay in matter. We introduce a modular Ps decay model implemented in GATE 9.4 and GATE 10, enabling the definition of an arbitrary number of decay channels…

A detection system of the conventional PET tomograph is set-up to record data from e+ e- annihilation into two photons with energy of 511 keV, and it gives information on the density distribution of a radiopharmaceutical in the body of the…

Purpose: 44Sc has been successfully produced, synthesized, labeled and first-in-human studies were conducted some years ago. The decay properties of 44Sc, together with being close to a clinical implementation, make it an ideal candidate…

Positronium Imaging requires two classes of events: double-coincidences originated from pair of back-to-back annihilation photons and triple-coincidences comprised with two annihilation photons and one additional prompt photon. The standard…

Medical Physics · Physics 2025-08-11 Lech Raczynski , Wojciech Krzemien , Konrad Klimaszewski

We develop a positronium imaging method for the Jagiellonian PET (J-PET) scanners based on the time-of-flight maximum likelihood expectation maximisation (TOF MLEM). The system matrix elements are calculated on-the-fly for the coincidences…

Instrumentation and Detectors · Physics 2023-10-19 Roman Y. Shopa , Kamil Dulski

Positron emission tomography (PET) is an important modality for diagnosing diseases such as cancer and Alzheimer's disease, capable of revealing the uptake of radiolabeled molecules that target specific pathological markers of the diseases.…

Medical Physics · Physics 2025-01-17 Hsin-Hsiung Huang , Zheyuan Zhu , Slun Booppasiri , Zhuo Chen , Shuo Pang , Chien-Min Kao

Human pose estimation, a vital task in computer vision, involves detecting and localising human joints in images and videos. While single-frame pose estimation has seen significant progress, it often fails to capture the temporal dynamics…

Computer Vision and Pattern Recognition · Computer Science 2025-01-27 Cesare Davide Pace , Alessandro Marco De Nunzio , Claudio De Stefano , Francesco Fontanella , Mario Molinara

The recent measurement of the lifetime of the free neutron using the beam method has an 8.7 s (4$\sigma$) discrepancy with UCN measurements. The goal of the BL3 experiment is to improve the statistical error of this measurement and help…

Instrumentation and Detectors · Physics 2020-10-23 A. W. Nelsen , E. G. Ballantyne , R. E. Calvert , C. B. Crawford , G. L. Greene , S. E. Vickers , F. E. Wietfeldt

The presence of tumor hypoxia is known to correlate with poor patient prognosis. Measurement of tissue oxygen concentration can be challenging, but recent advancements using positron annihilation lifetime spectroscopy (PALS) in…

Medical Physics · Physics 2025-01-22 Lucas Berens , Isaac Hsu , Chin-Tu Chen , Howard Halpern , Chien-Min Kao

Matrix completion and robust principal component analysis have been widely used for the recovery of data suffering from missing entries or outliers. In many real-world applications however, the data is also time-varying, and the naive…

Signal Processing · Electrical Eng. & Systems 2019-06-25 Charul , Uttkarsha Bhatt , Pravesh Biyani , Ketan Rajawat

Positron Annihilation Lifetime Spectroscopy (PALS) is a non-destructive radiological technique widely used in material science studies. PALS typically relies on an analog coincidence measurement setup and allows the estimate of the positron…

Instrumentation and Detectors · Physics 2019-08-14 Ming Fang , Nathan Bartholomew , Angela Di Fulvio

Most radiotracers used in dynamic positron emission tomography (PET) scanning act in a linear time-invariant fashion so that the measured time-course data are a convolution between the time course of the tracer in the arterial supply and…

Dense 3D convolutions provide high accuracy for perception but are too computationally expensive for real-time robotic systems. Existing tri-plane methods rely on 2D image features with interpolation, point-wise queries, and implicit MLPs,…

Robotics · Computer Science 2025-09-19 Sibaek Lee , Jiung Yeon , Hyeonwoo Yu

While the voxel-based methods have achieved promising results for multi-person 3D pose estimation from multi-cameras, they suffer from heavy computation burdens, especially for large scenes. We present Faster VoxelPose to address the…

Computer Vision and Pattern Recognition · Computer Science 2022-07-25 Hang Ye , Wentao Zhu , Chunyu Wang , Rujie Wu , Yizhou Wang

We present a nuclear medical imaging technique, employing triple-gamma trajectory intersections from beta^+ - gamma coincidences, able to reach sub-millimeter spatial resolution in 3 dimensions with a reduced requirement of reconstructed…

Medical Physics · Physics 2014-02-18 C. Lang , D. Habs , K. Parodi , P. G. Thirolf
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