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Reflecting the increasing interest in quantum computing, the variational quantum eigensolver (VQE) has attracted much attentions as a possible application of near-term quantum computers. Although the VQE has often been applied to quantum…

Quantum Physics · Physics 2022-12-07 Yasutaka Nishida , Fumihiko Aiga

Large climate-model ensembles are computationally expensive; yet many downstream analyses would benefit from additional, statistically consistent realizations of spatiotemporal climate variables. We study a generative modeling approach for…

Machine Learning · Computer Science 2026-01-06 Jacquelyn Shelton , Przemyslaw Polewski , Alexander Robel , Matthew Hoffman , Stephen Price

We develop Riemannian approaches to variational autoencoders (VAEs) for PDE-type ambient data with regularizing geometric latent dynamics, which we refer to as VAE-DLM, or VAEs with dynamical latent manifolds. We redevelop the VAE framework…

Machine Learning · Computer Science 2026-01-21 Andrew Gracyk

Automatic facial expression classification (FER) from videos is a critical problem for the development of intelligent human-computer interaction systems. Still, it is a challenging problem that involves capturing high-dimensional…

Computer Vision and Pattern Recognition · Computer Science 2016-07-22 Arnaud Dapogny , Kévin Bailly , Séverine Dubuisson

Variational autoencoders (VAEs), that are built upon deep neural networks have emerged as popular generative models in computer vision. Most of the work towards improving variational autoencoders has focused mainly on making the…

Machine Learning · Statistics 2016-11-17 Siddharth Agrawal , Ambedkar Dukkipati

Molecular generation conditioned on textual descriptions is a fundamental task in computational chemistry and drug discovery. Existing methods often struggle to simultaneously ensure high-quality, diverse generation and fast inference. In…

Machine Learning · Computer Science 2025-08-08 Md Atik Ahamed , Qiang Ye , Qiang Cheng

Modeling extreme precipitation and temperature is vital for understanding the impacts of climate change, as hazards like intense rainfall and record-breaking temperatures can result in severe consequences, including floods, droughts, and…

Methodology · Statistics 2026-01-13 Remy MacDonald , Benjamin Seiyon Lee , John Foley , Justin Lee

In recurrent survival analysis where the event of interest can occur multiple times for each subject, frailty models play a crucial role by capturing unobserved heterogeneity at the subject level within a population. Frailty models…

Methodology · Statistics 2024-10-30 Borna Bateni , Peyman Bateni , Bishwadeep Bhattacharyya , Devin Reeh

The estimation of rare event probabilities plays a pivotal role in diverse fields. Our aim is to determine the probability of a hazard or system failure occurring when a quantity of interest exceeds a critical value. In our approach, the…

Methodology · Statistics 2025-04-11 Lea Friedli , David Ginsbourger , Arnaud Doucet , Niklas Linde

The manifold assumption for high-dimensional data assumes that the data is generated by varying a set of parameters obtained from a low-dimensional latent space. Deep generative models (DGMs) are widely used to learn data representations in…

Machine Learning · Computer Science 2022-07-19 Krithika Iyer , Riddhish Bhalodia , Shireen Elhabian

Learning versatile, fine-grained representations from irregular event streams is pivotal yet nontrivial, primarily due to the heavy annotation that hinders scalability in dataset size, semantic richness, and application scope. To mitigate…

Computer Vision and Pattern Recognition · Computer Science 2026-03-05 Zhiwen Chen , Junhui Hou , Zhiyu Zhu , Jinjian Wu , Guangming Shi

Variational autoencoders (VAE) represent a popular, flexible form of deep generative model that can be stochastically fit to samples from a given random process using an information-theoretic variational bound on the true underlying…

Machine Learning · Computer Science 2019-10-08 Bin Dai , Yu Wang , John Aston , Gang Hua , David Wipf

In practical regression applications, multiple covariates are often measured, but not all may be associated with the response variable. Identifying and including only the relevant covariates in the model is crucial for improving prediction…

Methodology · Statistics 2026-03-10 Ana Carolina da Cruz , Camila P. E. de Souza , Pedro H. T. O. Sousa

Computing reactive trajectories and free energy (FE) landscapes associated to rare event kinetics is key to understanding the dynamics of complex systems. The analysis of the FE surface on which the underlying dynamics takes place has…

Statistical Mechanics · Physics 2018-12-05 François Sicard

In many machine learning tasks, input features with varying degrees of predictive capability are acquired at varying costs. In order to optimize the performance-cost trade-off, one would select features to observe a priori. However, given…

Machine Learning · Computer Science 2022-04-04 Randy Ardywibowo , Shahin Boluki , Zhangyang Wang , Bobak Mortazavi , Shuai Huang , Xiaoning Qian

The recently developed variational autoencoders (VAEs) have proved to be an effective confluence of the rich representational power of neural networks with Bayesian methods. However, most work on VAEs use a rather simple prior over the…

Machine Learning · Computer Science 2017-08-29 Prasoon Goyal , Zhiting Hu , Xiaodan Liang , Chenyu Wang , Eric Xing

Integrating physics models within machine learning models holds considerable promise toward learning robust models with improved interpretability and abilities to extrapolate. In this work, we focus on the integration of incomplete physics…

Machine Learning · Computer Science 2021-10-28 Naoya Takeishi , Alexandros Kalousis

We develop VSD, a method for conditioning a generative model of discrete, combinatorial designs on a rare desired class by efficiently evaluating a black-box (e.g. experiment, simulation) in a batch sequential manner. We call this task…

Machine Learning · Statistics 2025-11-24 Daniel M. Steinberg , Rafael Oliveira , Cheng Soon Ong , Edwin V. Bonilla

Generative models and those with computationally intractable likelihoods are widely used to describe complex systems in the natural sciences, social sciences, and engineering. Fitting these models to data requires likelihood-free inference…

Methodology · Statistics 2025-12-04 Rui Zhang , Oksana A. Chkrebtii , Dongbin Xiu

The detection of rare variants is important for understanding the genetic heterogeneity in mixed samples. Recently, next-generation sequencing (NGS) technologies have enabled the identification of single nucleotide variants (SNVs) in mixed…

Genomics · Quantitative Biology 2016-04-25 Fan Zhang , Patrick Flaherty