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Context-aware processing mechanisms have increasingly become a critical area of exploration for improving the semantic and contextual capabilities of language generation models. The Context-Aware Semantic Recomposition Mechanism (CASRM) was…

Computation and Language · Computer Science 2025-03-27 Richard Katrix , Quentin Carroway , Rowan Hawkesbury , Matthias Heathfield

Large Language Models (LLMs) have emerged as a promising paradigm for next-generation recommender systems, offering strong semantic understanding and natural-language reasoning abilities. Despite recent progress, current LLM-based…

Information Retrieval · Computer Science 2026-05-11 Shijun Li , Wooseong Yang , Yu Wang , Tianxin Wei , Joydeep Ghosh

Large language models (LLMs) integrated with autonomous agents hold significant potential for advancing scientific discovery through automated reasoning and task execution. However, applying LLM agents to drug discovery is still constrained…

Artificial Intelligence · Computer Science 2025-07-29 Kun Li , Zhennan Wu , Shoupeng Wang , Jia Wu , Shirui Pan , Wenbin Hu

Large language models (LLMs) have advanced the field of artificial intelligence (AI) and are a powerful enabler for interactive systems. However, they still face challenges in long-term interactions that require adaptation towards the user…

Artificial Intelligence · Computer Science 2025-05-20 Rebecca Westhäußer , Frederik Berenz , Wolfgang Minker , Sebastian Zepf

Large Language Models (LLMs) are constrained by their inability to process lengthy inputs, resulting in the loss of critical historical information. To address this limitation, in this paper, we propose the Self-Controlled Memory (SCM)…

Computation and Language · Computer Science 2025-03-19 Bing Wang , Xinnian Liang , Jian Yang , Hui Huang , Shuangzhi Wu , Peihao Wu , Lu Lu , Zejun Ma , Zhoujun Li

We present SCM (Sleep-Consolidated Memory), a research preview of a memory architecture for large language models that draws on neuroscientific principles to address a fundamental limitation in current systems: the absence of persistent,…

Machine Learning · Computer Science 2026-04-24 Saish Sachin Shinde

Large Language Model (LLM) has exhibited strong reasoning ability in text-based contexts across various domains, yet the limitation of context window poses challenges for the model on long-range inference tasks and necessitates a memory…

Information Retrieval · Computer Science 2026-03-11 Mengwei Yuan , Jianan Liu , Jing Yang , Xianyou Li , Weiran Yan , Yichao Wu , Penghao Liang

Importance: We introduce a novel Retrieval Augmented Generation (RAG)-Large Language Model (LLM) framework as a Clinical Decision Support Systems (CDSS) to support safe medication prescription. Objective: To evaluate the efficacy of…

Large Language Models (LLMs) often struggle with structural ambiguity in optimization problems, where a single problem admits multiple related but conflicting modeling paradigms, hindering effective solution generation. To address this, we…

Computation and Language · Computer Science 2026-04-23 Xinyu Zhang , Yuchen Wan , Boxuan Zhang , Zesheng Yang , Lingling Zhang , Bifan Wei , Jun Liu

Cascaded Automatic Speech Recognition -- Large Language Model (ASR-LLM) pipelines remain popular for industrial Spoken Dialogue Systems (SDS), primarily because their decoupled design ensures perceptual verifiability. However, cascaded…

Computation and Language · Computer Science 2026-05-26 Yizhou Peng , Ziyang Ma , Changsong Liu , Yi-Wen Chao , Xie Chen , Eng Siong Chng

Cognitive Diagnosis Models (CDMs) are designed to assess students' cognitive states by analyzing their performance across a series of exercises. However, existing CDMs often struggle with diagnosing infrequent students and exercises due to…

Artificial Intelligence · Computer Science 2025-02-11 Zhiang Dong , Jingyuan Chen , Fei Wu

Drug discovery is a complex and resource-intensive process, making early prediction of approval outcomes critical for optimizing research investments. While classical machine learning and deep learning methods have shown promise in drug…

Existing large language models (LLMs) can only afford fix-sized inputs due to the input length limit, preventing them from utilizing rich long-context information from past inputs. To address this, we propose a framework, Language Models…

Computation and Language · Computer Science 2023-06-13 Weizhi Wang , Li Dong , Hao Cheng , Xiaodong Liu , Xifeng Yan , Jianfeng Gao , Furu Wei

Unlike professional caregivers, family caregivers often assume this role without formal preparation or training. Because of this, there is an urgent need to enhance the capacity of family caregivers to provide quality care. Large language…

Computation and Language · Computer Science 2024-03-12 Bambang Parmanto , Bayu Aryoyudanta , Wilbert Soekinto , I Made Agus Setiawan , Yuhan Wang , Haomin Hu , Andi Saptono , Yong K. Choi

LLM-based agents show strong potential for long-horizon reasoning, yet their context size is limited by deployment factors (e.g., memory, latency, and cost), yielding a constrained context budget. As interaction histories grow, this induces…

Artificial Intelligence · Computer Science 2026-04-03 Yong Wu , YanZhao Zheng , TianZe Xu , ZhenTao Zhang , YuanQiang Yu , JiHuai Zhu , Chao Ma , BinBin Lin , BaoHua Dong , HangCheng Zhu , RuoHui Huang , Gang Yu

Clinical decision-making is a dynamic, interactive, and cyclic process where doctors have to repeatedly decide on which clinical action to perform and consider newly uncovered information for diagnosis and treatment. Large Language Models…

Computation and Language · Computer Science 2026-03-03 David Bani-Harouni , Chantal Pellegrini , Ege Özsoy , Nassir Navab , Matthias Keicher

Recent progress in Large Language Models (LLMs) has drawn attention to their potential for accelerating drug discovery. However, a central problem remains: translating theoretical ideas into robust implementations in the highly specialized…

Machine Learning · Computer Science 2025-03-06 Sizhe Liu , Yizhou Lu , Siyu Chen , Xiyang Hu , Jieyu Zhao , Yingzhou Lu , Yue Zhao

Equipping large language models (LLMs) with search engines via reinforcement learning (RL) has emerged as an effective approach for building search agents. However, overreliance on search introduces unnecessary cost and risks exposure to…

Computation and Language · Computer Science 2025-12-19 Tzu-Han Lin , Wei-Lin Chen , Chen-An Li , Hung-yi Lee , Yun-Nung Chen , Yu Meng

Drug discovery remains a formidable challenge: more than 90 percent of candidate molecules fail in clinical evaluation, and development costs often exceed one billion dollars per approved therapy. Disparate data streams, from genomics and…

Artificial Intelligence · Computer Science 2025-04-28 Kevin Song , Andrew Trotter , Jake Y. Chen

Large language models (LLMs) have emerged as effective action policies for sequential decision-making (SDM) tasks due to their extensive prior knowledge. However, this broad yet general knowledge is often insufficient for specific…

Machine Learning · Computer Science 2025-10-01 Xue Yan , Zijing Ou , Mengyue Yang , Yan Song , Haifeng Zhang , Yingzhen Li , Jun Wang
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