Related papers: Constraint-Aware Corrective Memory for Language-Ba…

Effective memory management is essential for large language model (LLM) agents handling long-term interactions. Current memory frameworks typically treat agents as passive "recorders" and retrieve information without understanding its…

Multi-agent systems built on Large Language Models (LLMs) show exceptional promise for complex collaborative problem-solving, yet they face fundamental challenges stemming from context window limitations that impair memory consistency, role…

Randomized experiments or randomized controlled trials (RCTs) are gold standards for causal inference, yet cost and sample-size constraints limit power. We introduce CALM (Causal Analysis leveraging Language Models), a statistical framework…

Large Language Models (LLMs) have the potential to accelerate small molecule drug design due to their ability to reason about information from diverse sources and formats. However, their practical utility remains unclear due to the lack of…

Large language models (LLMs) have achieved remarkable performance on diverse benchmarks, yet existing evaluation practices largely rely on coarse summary metrics that obscure underlying reasoning abilities. In this work, we propose novel…

Recent advances in Transformer-based large language models (LLMs) have led to significant performance improvements across many tasks. These gains come with a drastic increase in the models' size, potentially leading to slow and costly use…

Despite the rapid expansion of Large Language Models (LLMs) in healthcare, robust and explainable evaluation of their ability to assess clinical trial reporting according to CONSORT standards remains an open challenge. In particular,…

We present a modular framework powered by large language models (LLMs) that automates and streamlines key tasks across the early-stage computational drug discovery pipeline. By combining LLM reasoning with domain-specific tools, the…

Motivated by the challenge to improve the adversarial robustness, security, and trust of medical decision making intelligent agents, this study develops a full-link security enhancement framework, which describes "input risk perception -…

The evaluation of large language models (LLMs) has predominantly relied on static datasets, which offer limited scalability and fail to capture the evolving reasoning capabilities of recent models. To overcome these limitations, we propose…

Recent advances in Large Language Model (LLM)-based agents have been propelled by Retrieval-Augmented Generation (RAG), which grants the models access to vast external knowledge bases. Despite RAG's success in improving agent performance,…

Long-context memory systems often fail under fixed budgets, but end-to-end evaluation does not reveal whether evidence was discarded during compression or preserved but never retrieved. We introduce a four-condition diagnostic protocol that…

The efficiency of large language models (LLMs) is fundamentally limited by their sequential, token-by-token generation process. We argue that overcoming this bottleneck requires a new design axis for LLM scaling: increasing the semantic…

Large language model (LLM)-based coding agents increasingly rely on external memory to reuse prior debugging experience, repair traces, and repository-local operational knowledge. However, retrieved memory is useful only when the current…

Drug discovery frequently loses momentum when data, expertise, and tools are scattered, slowing design cycles. To shorten this loop we built a hierarchical, tool using agent framework that automates molecular optimisation. A Principal…

Large language model (LLM)-powered multi-agent systems (MAS) demonstrate remarkable collective intelligence, wherein multi-agent memory serves as a pivotal mechanism for continual adaptation. However, existing multi-agent memory designs…

General-purpose large language models (LLMs) that rely on in-context learning do not reliably deliver the scientific understanding and performance required for drug discovery tasks. Simply increasing model size or introducing reasoning…

Background: Cognitive biases in clinical decision-making significantly contribute to errors in diagnosis and suboptimal patient outcomes. Addressing these biases presents a formidable challenge in the medical field. Objective: This study…

Large Language Models (LLMs) have made extraordinary progress in the field of Artificial Intelligence and have demonstrated remarkable capabilities across a large variety of tasks and domains. However, as we venture closer to creating…

Long-term multi-agent systems inevitably generate vast amounts of trajectories and historical interactions, which makes efficient memory management essential for both performance and scalability. Existing methods typically depend on vector…