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Single-cell sequencing technology maps cells to a high-dimensional space encoding their internal activity. Recently-proposed virtual cell models extend this concept, enriching cells' representations based on patterns learned from…

Quantitative Methods · Quantitative Biology 2025-11-03 William Gilpin

Gene finding is the task of identifying the locations of coding sequences within the vast amount of genetic code contained in the genome. With an ever increasing quantity of raw genome sequences, gene finding is an important avenue towards…

Genomics · Quantitative Biology 2025-05-07 Frederikke I. Marin , Dennis Pultz , Wouter Boomsma

Vision-Language Models (VLMs) are powerful tools for processing and understanding text and images. We study the processing of visual tokens in the language model component of LLaVA, a prominent VLM. Our approach focuses on analyzing the…

Computer Vision and Pattern Recognition · Computer Science 2025-04-29 Clement Neo , Luke Ong , Philip Torr , Mor Geva , David Krueger , Fazl Barez

Large language models (LLMs) can spell out tokens character by character with high accuracy, yet they struggle with more complex character-level tasks, such as identifying compositional subcomponents within tokens. In this work, we…

Computation and Language · Computer Science 2025-06-13 Tatsuya Hiraoka , Kentaro Inui

The predominant approach for language modeling is to process sequences from left to right, but this eliminates a source of information: the order by which the sequence was generated. One strategy to recover this information is to decode…

Computation and Language · Computer Science 2021-11-01 Xuanlin Li , Brandon Trabucco , Dong Huk Park , Michael Luo , Sheng Shen , Trevor Darrell , Yang Gao

We consider the protein sequence engineering problem, which aims to find protein sequences with high fitness levels, starting from a given wild-type sequence. Directed evolution has been a dominating paradigm in this field which has an…

Machine Learning · Computer Science 2025-01-20 Yinkai Wang , Jiaxing He , Yuanqi Du , Xiaohui Chen , Jianan Canal Li , Li-Ping Liu , Xiaolin Xu , Soha Hassoun

Disentangling the encodings of neural models is a fundamental aspect for improving interpretability, semantic control and downstream task performance in Natural Language Processing. Currently, most disentanglement methods are unsupervised…

Computation and Language · Computer Science 2023-02-17 Danilo S. Carvalho , Giangiacomo Mercatali , Yingji Zhang , Andre Freitas

Large language models compress heterogeneous knowledge into a single parameter space, allowing facts from different domains to interfere during generation. We propose DALM, a Domain-Algebraic Language Model that replaces unconstrained token…

Computation and Language · Computer Science 2026-04-20 Chao Li

Structured data, prevalent in tables, databases, and knowledge graphs, poses a significant challenge in its representation. With the advent of large language models (LLMs), there has been a shift towards linearization-based methods, which…

Computation and Language · Computer Science 2024-04-04 Yutong Shao , Ndapa Nakashole

Combining large language models with evolutionary computation algorithms represents a promising research direction leveraging the remarkable generative and in-context learning capabilities of LLMs with the strengths of evolutionary…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Tobias Preintner , Weixuan Yuan , Adrian König , Thomas Bäck , Elena Raponi , Niki van Stein

Protein language models (PLMs) encode rich biological information, yet their internal neuron representations are poorly understood. We introduce the first automated framework for labeling every neuron in a PLM with biologically grounded…

Machine Learning · Computer Science 2025-07-10 Arjun Banerjee , David Martinez , Camille Dang , Ethan Tam

Discrete audio tokens derived from self-supervised learning models have gained widespread usage in speech generation. However, current practice of directly utilizing audio tokens poses challenges for sequence modeling due to the length of…

Sound · Computer Science 2024-01-17 Feiyu Shen , Yiwei Guo , Chenpeng Du , Xie Chen , Kai Yu

Contextual adaptation in token embeddings plays a central role in determining how well language models maintain coherence and retain semantic relationships over extended text sequences. Static embeddings often impose constraints on lexical…

Computation and Language · Computer Science 2025-03-27 Koinis Vassilis , Godfrey Milbourne , Harriet Featherstone , Xanthe Peverell , Yorick Bletchley , Zachary Montford

Gender-inclusive NLP research has documented the harmful limitations of gender binary-centric large language models (LLM), such as the inability to correctly use gender-diverse English neopronouns (e.g., xe, zir, fae). While data scarcity…

Computation and Language · Computer Science 2024-04-09 Anaelia Ovalle , Ninareh Mehrabi , Palash Goyal , Jwala Dhamala , Kai-Wei Chang , Richard Zemel , Aram Galstyan , Yuval Pinter , Rahul Gupta

Ontologies and knowledge graphs require continuous evolution to remain comprehensive and accurate, but manual curation is labor intensive. Large Language Models (LLMs) possess vast unstructured knowledge but struggle with maintaining…

Artificial Intelligence · Computer Science 2025-07-30 Vishal Raman , Vijai Aravindh R

Current language models (LMs) use a fixed, static subword tokenizer. This default choice typically results in degraded efficiency and language capabilities, especially in languages other than English. To address this issue, we challenge the…

Computation and Language · Computer Science 2025-06-12 Darius Feher , Ivan Vulić , Benjamin Minixhofer

Speech language models refer to language models with speech processing and understanding capabilities. One key desirable capability for speech language models is the ability to capture the intricate interdependency between content and…

Computation and Language · Computer Science 2025-08-11 Kaizhi Qian , Xulin Fan , Junrui Ni , Slava Shechtman , Mark Hasegawa-Johnson , Chuang Gan , Yang Zhang

Diffusion models, widely used in image generation, rely on iterative refinement to generate images from noise. Understanding this data evolution is important for model development and interpretability, yet challenging due to its…

Computer Vision and Pattern Recognition · Computer Science 2024-12-12 Vidya Prasad , Hans van Gorp , Christina Humer , Ruud J. G. van Sloun , Anna Vilanova , Nicola Pezzotti

Medical coding, the translation of unstructured clinical text into standardized medical codes, is a crucial but time-consuming healthcare practice. Though large language models (LLM) could automate the coding process and improve the…

Computation and Language · Computer Science 2025-03-25 John Wu , David Wu , Jimeng Sun

Large pre-trained language models have recently been expanded and applied to programming language tasks with great success, often through further pre-training of a strictly-natural language model--where training sequences typically contain…

Computation and Language · Computer Science 2024-02-13 Fenia Christopoulou , Guchun Zhang , Gerasimos Lampouras