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Related papers: EvoLen: Evolution-Guided Tokenization for DNA Lang…

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Speech tokenization serves as the foundation of speech language model (LM), enabling them to perform various tasks such as spoken language modeling, text-to-speech, speech-to-text, etc. Most speech tokenizers are trained independently of…

Computation and Language · Computer Science 2024-09-11 Arnon Turetzky , Yossi Adi

Large language models (LLMs) trained on text demonstrated remarkable results on natural language processing (NLP) tasks. These models have been adapted to decipher the language of DNA, where sequences of nucleotides act as "words" that…

Generative modeling for protein engineering is key to solving fundamental problems in synthetic biology, medicine, and material science. We pose protein engineering as an unsupervised sequence generation problem in order to leverage the…

Deep neural networks (DNNs) are known for extracting useful information from large amounts of data. However, the representations learned in DNNs are typically hard to interpret, especially in dense layers. One crucial issue of the classical…

Neural and Evolutionary Computing · Computer Science 2021-05-06 Yuyang Gao , Giorgio A. Ascoli , Liang Zhao

This paper explores the possibility of learning custom tokens for representing new concepts in Vision-Language Models (VLMs). Our aim is to learn tokens that can be effective for both discriminative and generative tasks while composing well…

Computer Vision and Pattern Recognition · Computer Science 2025-02-18 Pramuditha Perera , Matthew Trager , Luca Zancato , Alessandro Achille , Stefano Soatto

Fine-tuning LLMs for classification typically maps inputs directly to labels. We ask whether attaching brief explanations to each label during fine-tuning yields better models. We evaluate conversational response quality along three axes:…

Machine Learning · Computer Science 2026-03-03 Vivswan Shah , Randy Cogill , Hanwei Yue , Gopinath Chennupati , Rinat Khaziev

Pre-trained models have achieved remarkable success in natural language processing (NLP). However, existing pre-training methods underutilize the benefits of language understanding for generation. Inspired by the idea of Generative…

Computation and Language · Computer Science 2023-05-10 Jian Yang , Shuming Ma , Li Dong , Shaohan Huang , Haoyang Huang , Yuwei Yin , Dongdong Zhang , Liqun Yang , Furu Wei , Zhoujun Li

Major progress on language models (LMs) in recent years has largely resulted from moving away from specialized models designed for specific tasks, to general models based on powerful architectures (e.g. the Transformer) that learn…

Machine Learning · Computer Science 2025-07-16 Sukjun Hwang , Brandon Wang , Albert Gu

Subword tokenization methods, such as Byte-Pair Encoding (BPE), significantly impact the performance and efficiency of large language models (LLMs). The standard approach involves training a general-purpose tokenizer that uniformly…

Computation and Language · Computer Science 2026-01-30 Vijini Liyanage , François Yvon

Pipelined NLP systems have largely been superseded by end-to-end neural modeling, yet nearly all commonly-used models still require an explicit tokenization step. While recent tokenization approaches based on data-derived subword lexicons…

Computation and Language · Computer Science 2022-05-19 Jonathan H. Clark , Dan Garrette , Iulia Turc , John Wieting

Token representation strategies within large-scale neural architectures often rely on contextually refined embeddings, yet conventional approaches seldom encode structured relationships explicitly within token interactions. Self-attention…

Computation and Language · Computer Science 2025-03-27 James Blades , Frederick Somerfield , William Langley , Susan Everingham , Maurice Witherington

Recent genomic foundation models largely adopt large language model architectures that treat DNA as a one-dimensional token sequence. However, exhaustive sequential reading is structurally misaligned with sparse and discontinuous genomic…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Hongxin Xiang , Pengsen Ma , Yunkang Cao , Di Yu , Haowen Chen , Xinyu Yang , Xiangxiang Zeng

Tokenization is associated with many poorly understood shortcomings in language models (LMs), yet remains an important component for long sequence scaling purposes. This work studies how tokenization impacts model performance by analyzing…

Computation and Language · Computer Science 2025-04-15 Buu Phan , Brandon Amos , Itai Gat , Marton Havasi , Matthew Muckley , Karen Ullrich

Transformer-based language models often achieve strong results on mathematical reasoning benchmarks while remaining fragile on basic numerical understanding and arithmetic operations. A central limitation is that numbers are processed as…

Computation and Language · Computer Science 2026-01-15 Andreea Dutulescu , Stefan Ruseti , Mihai Dascalu

We consider controllable DNA sequence design, where sequences are generated by conditioning on specific biological properties. While language models (LMs) such as GPT and BERT have achieved remarkable success in natural language generation,…

Machine Learning · Computer Science 2025-12-10 Xingyu Su , Xiner Li , Yuchao Lin , Ziqian Xie , Degui Zhi , Shuiwang Ji

Tokenization imposes a fixed granularity on the input text, freezing how a language model operates on data and how far in the future it predicts. Byte Pair Encoding (BPE) and similar schemes split text once, build a static vocabulary, and…

Computation and Language · Computer Science 2025-06-18 Mathurin Videau , Badr Youbi Idrissi , Alessandro Leite , Marc Schoenauer , Olivier Teytaud , David Lopez-Paz

Natural Language Processing (NLP) has transformed various fields beyond linguistics by applying techniques originally developed for human language to the analysis of biological sequences. This review explores the application of NLP methods…

Computation and Language · Computer Science 2025-06-04 Ella Rannon , David Burstein

RNA plays a pivotal role in translating genetic instructions into functional outcomes, underscoring its importance in biological processes and disease mechanisms. Despite the emergence of numerous deep learning approaches for RNA,…

Quantitative Methods · Quantitative Biology 2024-12-13 Yuchen Ren , Zhiyuan Chen , Lifeng Qiao , Hongtai Jing , Yuchen Cai , Sheng Xu , Peng Ye , Xinzhu Ma , Siqi Sun , Hongliang Yan , Dong Yuan , Wanli Ouyang , Xihui Liu

The differing representation spaces required for visual understanding and generation pose a challenge in unifying them within the autoregressive paradigm of large language models. A vision tokenizer trained for reconstruction excels at…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Wei Song , Yuran Wang , Zijia Song , Yadong Li , Zenan Zhou , Long Chen , Jianhua Xu , Jiaqi Wang , Kaicheng Yu

We introduce AudioLM, a framework for high-quality audio generation with long-term consistency. AudioLM maps the input audio to a sequence of discrete tokens and casts audio generation as a language modeling task in this representation…

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