Related papers: Predicting Mesoscopic Larmor Frequency Shifts in E…
Magnetic susceptibility imaging may provide valuable information about chemical composition and microstructural organization of tissue. However, its estimation from the MRI signal phase is particularly difficult as it is sensitive to…
This study aims to validate if MRI can measure anisotropic mesoscopic Larmor frequency shifts from white matter axonal microstructure relative to the B0 direction and if dMRI can estimate this anisotropy. Recent models describe how…
Accurate estimation of microscopic magnetic field variations induced in biological tissue can be valuable for mapping tissue composition in health and disease. Here, we present an extension to Quantitative susceptibility mapping (QSM) to…
In biological tissue, MR transverse relaxation stems from mechanisms spanning multiple scales, from molecular dipole-dipole interactions to mesoscopic field variations driven by tissue microstructure. While mesoscopic relaxation reflects…
Purpose: To investigate the effect of anisotropic magnetic microstructure on the measurable Larmor frequency offset in media with heterogeneous magnetic susceptibility. Specific objectives were (i) validation of recently developed theory…
Optical detection of magnetic resonance using quantum spin sensors (QSS) provides a spatially local and sensitive technique to probe spin dynamics in magnets. However, its utility as a probe of antiferromagnetic resonance (AFMR) remains an…
Quantitative susceptibility mapping (QSM) is a magnetic resonance imaging (MRI) technique that estimates magnetic susceptibility of tissue from Larmor frequency offset measurements. The generation of QSM requires solving a challenging…
In the human brain, essential iron molecules for proper neurological functioning exist in transferrin (tf) and ferritin (Fe3) forms. However, its unusual increment manifests iron overload, which reacts with hydrogen peroxide. This reaction…
We present a theoretical framework for the NMR and MRI measured Larmor frequency in media with magnetized microstructure using the mesoscopic Lorentz sphere and the principle of coarse graining. We obtain an analytical expression for…
Purpose: To investigate the effect of realistic microstructural geometry on the susceptibility-weighted magnetic resonance (MR) signal in white matter (WM), with application to demyelination. Methods: Previous work has modeled…
Background: Quantitative susceptibility mapping (QSM) of the brain is an advanced MRI technique for assessing tissue characteristics based on magnetic susceptibility, which varies with the composition of the tissue, such as iron, calcium,…
The torsional vibration of atomic force microscope (AFM) cantilevers is critical for high-sensitivity measurements, yet existing models for width-varying cantilevers often rely on approximations that lead to significant discrepancies with…
The Larmor frequency shift is found in porous media consisting of NMR-reporting fluid filling a connected pore within an NMR-invisible matrix for the case of fast diffusion in the fluid. The matrix material has a distinct…
Brain mechanics is a topic of deep interest because of the significant role of mechanical cues in both brain function and form. Specifically, capturing the heterogeneous and anisotropic behaviour of cerebral white matter (WM) is extremely…
Quantitative susceptibility mapping (QSM) is a valuable magnetic resonance imaging (MRI) contrast mechanism that has demonstrated broad clinical applications. However, the image reconstruction of QSM is challenging due to its ill-posed…
Purpose: To separate the effects of magnetic susceptibility and chemical shift/exchange in a phantom with isotropic magnetic susceptibility. To generate a chemical shift/exchange-corrected quantitative susceptibility mapping (QSM) result.…
Quantitative susceptibility mapping (QSM) utilizes MRI signal phase to infer estimates of local tissue magnetism (magnetic susceptibility), which has been shown useful to provide novel image contrast and as biomarkers of abnormal tissue.…
Estimating magnetic susceptibility using MRI depends on inverting a forward relationship between the susceptibility and measured Larmor frequency. However, an often-overlooked constraint in susceptibility fitting is that the Larmor…
Quantitative Susceptibility Mapping (QSM) estimates tissue magnetic susceptibility distributions from Magnetic Resonance (MR) phase measurements by solving an ill-posed dipole inversion problem. Conventional single orientation QSM methods…
Quantitative Magnetic Resonance Imaging (qMRI) provides researchers insight into pathological and physiological alterations of living tissue, with the help of which researchers hope to predict (local) therapeutic efficacy early and…