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Genetic regulatory networks with adaptive responses are widely studied in biology. Usually, models consisting only of a few nodes have been considered. They present one input receptor for activation and one output node where the adaptive…

Molecular Networks · Quantitative Biology 2016-07-20 Pablo Kaluza , Masayo Inoue

In Systems Biology there is a growing interest in the question, whether or not a given mathematical model can admit more than one steady state. As parameter values are often unknown or subject to a very high uncertainty, one is often…

Other Quantitative Biology · Quantitative Biology 2009-09-23 Carsten Conradi

Many dynamical systems arising in biology and other areas exhibit multistationarity (two or more positive steady states with the same conserved quantities). Although deciding multistationarity for a polynomial dynamical system is an…

Molecular Networks · Quantitative Biology 2019-02-08 Alicia Dickenstein , Mercedes Perez Millan , Anne Shiu , Xiaoxian Tang

The present paper aims to demonstrate the usage of Convolutional Neural Networks as a generative model for stochastic processes, enabling researchers from a wide range of fields (such as quantitative finance and physics) to develop a…

Machine Learning · Statistics 2018-01-12 Fernando Fernandes Neto

This paper investigates the suitability of using Generative Adversarial Networks (GANs) to generate stable structures for the physics-based puzzle game Angry Birds. While previous applications of GANs for level generation have been mostly…

Machine Learning · Computer Science 2023-09-07 Frederic Abraham , Matthew Stephenson

Topological order has been proposed to go beyond Landau symmetry breaking theory for more than twenty years. But it is still a challenging problem to generally detect it in a generic many-body state. In this paper, we will introduce a…

Strongly Correlated Electrons · Physics 2014-11-19 Huan He , Heidar Moradi , Xiao-Gang Wen

The functions of many networked systems in physics, biology or engineering rely on a coordinated or synchronized dynamics of its constituents. In power grids for example, all generators must synchronize and run at the same frequency and…

Adaptation and Self-Organizing Systems · Physics 2017-09-13 Debsankha Manik , Marc Timme , Dirk Witthaut

Open dynamical systems are mathematical models of machines that take input, change their internal state, and produce output. For example, one may model anything from neurons to robots in this way. Several open dynamical systems can be…

Dynamical Systems · Mathematics 2016-02-25 David I. Spivak

Complex dynamical systems are often modeled as networks, with nodes representing dynamical units which interact through the network's links. Gene regulatory networks, responsible for the production of proteins inside a cell, are an example…

Statistical Mechanics · Physics 2009-09-30 Zoran Levnajić

In this paper we investigate equilibria of continuous differential equation models of network dynamics. The motivation comes from gene regulatory networks where each directed edge represents either down- or up-regulation, and is modeled by…

Dynamical Systems · Mathematics 2021-07-08 William Duncan , Tomas Gedeon , Hiroshi Kokubu , Konstantin Mischaikow , Hiroe Oka

A scheme for logical computation using non-linear dynamical systems is presented. Examples of discrete-time maps configured as AND, OR, NAND and NOR gates are given. It is seen that the logical operations are flexible in the sense that an…

Chaotic Dynamics · Physics 2007-05-23 Madhekar Suneel

Gating mechanisms are widely used in neural network models, where they allow gradients to backpropagate more easily through depth or time. However, their saturation property introduces problems of its own. For example, in recurrent models…

Neural and Evolutionary Computing · Computer Science 2020-06-22 Albert Gu , Caglar Gulcehre , Tom Le Paine , Matt Hoffman , Razvan Pascanu

Graph representations offer powerful and intuitive ways to describe data in a multitude of application domains. Here, we consider stochastic processes generating graphs and propose a methodology for detecting changes in stationarity of such…

Machine Learning · Computer Science 2021-02-11 Daniele Zambon , Cesare Alippi , Lorenzo Livi

We consider the problem of state selection for a stochastic system, initially in an unstable stationary state, when multiple metastable states compete for occupation. Using path-integral techniques we derive remarkably simple and accurate…

Statistical Mechanics · Physics 2008-02-03 Martin B. Tarlie , Alan J. McKane

Mathematical models of stem cell differentiation are commonly based upon the concept of subsequent cell fate decisions, each controlled by a gene regulatory network. These networks exhibit a multistable behavior and cause the system to…

Quantitative Methods · Quantitative Biology 2011-07-06 Christian Breindl , Daniella Schittler , Steffen Waldherr , Frank Allgöwer

Graph Neural Networks (GNNs) is an architecture for structural data, and has been adopted in a mass of tasks and achieved fabulous results, such as link prediction, node classification, graph classification and so on. Generally, for a…

Machine Learning · Computer Science 2022-05-12 Ye Tang , Xuesong Yang , Xinrui Liu , Xiwei Zhao , Zhangang Lin , Changping Peng

Training large-scale generative models is resource-intensive and relies heavily on heuristic dataset weighting. We address two fundamental questions: Can we train Large Language Models (LLMs) modularly-combining small, domain-specific…

Machine Learning · Computer Science 2026-02-25 Corinna Cortes , Mehryar Mohri , Yutao Zhong

Gated networks are networks that contain gating connections, in which the outputs of at least two neurons are multiplied. Initially, gated networks were used to learn relationships between two input sources, such as pixels from two images.…

Machine Learning · Computer Science 2015-12-11 Olivier Sigaud , Clément Masson , David Filliat , Freek Stulp

This work addresses whether a reaction network, taken with mass-action kinetics, is multistationary, that is, admits more than one positive steady state in some stoichiometric compatibility class. We build on previous work on the effect…

Molecular Networks · Quantitative Biology 2019-08-27 AmirHosein Sadeghimanesh , Elisenda Feliu

A framework to learn a multi-modal distribution is proposed, denoted as the Conditional Quantum Generative Adversarial Network (C-qGAN). The neural network structure is strictly within a quantum circuit and, as a consequence, is shown to…

Quantum Physics · Physics 2023-10-20 Salvatore Certo , Anh Pham , Nicolas Robles , Andrew Vlasic