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Artificial intelligence (AI) is entering medical imaging, mainly enhancing image reconstruction. Nevertheless, improvements throughout the entire processing, from signal detection to computation, potentially offer significant benefits. This…

Machine Learning · Computer Science 2023-10-27 Stephan Naunheim , Yannick Kuhl , David Schug , Volkmar Schulz , Florian Mueller

We propose a magnetic resonance (MR)-based method for estimation of continuous linear attenuation coefficients (LAC) in positron emission tomography (PET) using a physical compartmental model and ultrashort echo time (UTE)/multi-echo Dixon…

Positron Emission Tomography (PET) scanners are usually designed with the goal to obtain the best compromise between sensitivity, resolution, field-of-view size, and cost. Therefore, it is difficult to improve the resolution of a PET…

Medical Physics · Physics 2023-07-18 Pablo Galve , Alejandro Lopez-Montes , Jose M Udias , Stephen C Moore , Joaquin L Herraiz

With the growth of interest in network data across fields, the Exponential Random Graph Model (ERGM) has emerged as the leading approach to the statistical analysis of network data. ERGM parameter estimation requires the approximation of an…

Computation · Statistics 2017-08-10 Christian S. Schmid , Bruce A. Desmarais

Improving the coincidence time resolution (CTR) of time-of-flight positron emission tomography (TOF-PET) systems to achieve a higher signal-to-noise ratio (SNR) gain or even direct positron emission imaging (dPEI) is of paramount importance…

Recent studies of positron emission tomography (PET) devices have shown that the detection of polarization-correlated annihilation quanta can potentially reduce the background and creation of false lines of response (LORs) leading to…

Positron emission tomography (PET) is widely utilized for cancer detection due to its ability to visualize functional and biological processes in vivo. PET images are usually reconstructed from histogrammed raw data (sinograms) using…

Image and Video Processing · Electrical Eng. & Systems 2024-11-26 Yiran Sun , Osama Mawlawi

Semi monolithic detector designs with a series of stacked thin monolithic scintillator plates and side readout are an attractive approach for potentially achieving very high performance in a positron emission tomography (PET) scanner. In…

Instrumentation and Detectors · Physics 2025-02-12 Shiv K. Subedi , Simon R. Cherry , Yi Qiang , Peng Peng

Two major challenges in time-of-flight positron emission tomography (TOF-PET) are low spatial resolution and high radioactive dose to the patient, both of which result from limitations in detection technology rather than fundamental…

We present an asymptotic analysis of the minimum probability of error (MPE) in inferring the correct hypothesis in a Bayesian multi-hypothesis testing (MHT) formalism using many pixels of data that are corrupted by signal dependent shot…

Optics · Physics 2015-06-19 Sudhakar Prasad

We study maximum likelihood estimation in log-linear models under conditional Poisson sampling schemes. We derive necessary and sufficient conditions for existence of the maximum likelihood estimator (MLE) of the model parameters and…

Statistics Theory · Mathematics 2012-07-24 Stephen E. Fienberg , Alessandro Rinaldo

We report on an hybrid in-beam PET and prompt-gamma Compton imaging system aimed at quasi real-time ion-range verification in proton-therapy treatments. Proof-of-concept experiments were carried out at the radiobiology beam line of the CNA…

For the tree topology, previous studies show the maximum likelihood estimate (MLE) of a link/path takes a polynomial form with a degree that is one less than the number of descendants connected to the link/path. Since then, the main concern…

Networking and Internet Architecture · Computer Science 2010-04-28 Weiping Zhu

We study maximum likelihood estimation (MLE) in the generalized group orbit recovery model, where each observation is generated by applying a random group action and a known, fixed linear operator to an unknown signal, followed by additive…

Statistics Theory · Mathematics 2025-09-30 Sheng Xu , Anderson Ye Zhang , Amit Singer

Aims. Deriving accurate frequencies, amplitudes, and mode lifetimes from stochastically driven pulsation is challenging, more so, if one demands that realistic error estimates be given for all model fitting parameters. As has been shown by…

Astrophysics · Physics 2015-05-13 M. Gruberbauer , T. Kallinger , W. W. Weiss , D. B. Guenther

Over the last decades, the family of $\alpha$-stale distributions has proven to be useful for modelling in telecommunication systems. Particularly, in the case of radar applications, finding a fast and accurate estimation for the amplitude…

Methodology · Statistics 2023-11-15 Mahdi Teimouri

MultiModal Imaging is an innovative technique that consists in the combination of diagnostic exams based on different physical processes, to obtain a unique image with more detailed clinical information. The possibility of a simultaneous…

Medical Physics · Physics 2020-06-23 A. Colombi , F. Barbaro , L. Canton , M. P. Carante , A. Fontana

Pseudo log-likelihood is a type of maximum likelihood estimation (MLE) method used in various fields including contextual bandits, influence maximization of social networks, and causal bandits. However, in previous literature…

Machine Learning · Computer Science 2024-03-28 Shi Feng , Nuoya Xiong , Zhijie Zhang , Wei Chen