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Clinical decision-making requires reasoning over incomplete, imprecise, and linguistically expressed patient narratives. While large language models (LLMs) excel at extracting latent information from natural language, they lack the…
Artificial intelligence (AI) has demonstrated strong potential in clinical diagnostics, often achieving accuracy comparable to or exceeding that of human experts. A key challenge, however, is that AI reasoning frequently diverges from…
With the rapid growth of large language models (LLMs) and vision-language models (VLMs) in medicine, simply integrating clinical text and medical imaging does not guarantee reliable reasoning. Existing multimodal models often produce…
Automated mental health prediction using textual data has shown promising results with deep learning and large language models. However, deploying these models in high-stakes real-world settings remains challenging, as existing approaches…
Medicine is rife with high-stakes uncertainty. Doctors routinely make clinical judgments and decisions that juggle many fundamental unknowns, like predictions about what might be causing a patients' symptoms or decisions about what…
Despite the remarkable capabilities of large language models (LLMs) across a range of tasks, mathematical reasoning remains a challenging frontier. Motivated by the observation that humans learn more effectively when prompted not what to…
Machine reasoning has made great progress in recent years owing to large language models (LLMs). In the clinical domain, however, most NLP-driven projects mainly focus on clinical classification or reading comprehension, and under-explore…
Recent progress in multimodal large language models (MLLMs) has demonstrated promising performance on medical benchmarks and in preliminary trials as clinical assistants. Yet, our pilot audit of diagnostic cases uncovers a critical failure…
As Large Language Models (LLMs) achieve significant breakthroughs in complex reasoning tasks, evaluating their proficiency in science, technology, engineering, and mathematics (STEM) has become a primary method for measuring machine…
The symptom checking systems inquire users for their symptoms and perform a rapid and affordable medical assessment of their condition. The basic symptom checking systems based on Bayesian methods, decision trees, or information gain…
The diagnosis of oral diseases presents a problematic clinical challenge, characterized by a wide spectrum of pathologies with overlapping symptomatology. To address this, we developed Clinical Semantic Intelligence (CSI), a novel…
Analogical Reasoning problems challenge both connectionist and symbolic AI systems as these entail a combination of background knowledge, reasoning and pattern recognition. While symbolic systems ingest explicit domain knowledge and perform…
The emergence of groundbreaking large language models capable of performing complex reasoning tasks holds significant promise for addressing various scientific challenges, including those arising in complex clinical scenarios. To enable…
We present PULSE, a medical reasoning agent that combines a domain-tuned large language model with scientific literature retrieval to support diagnostic decision-making in complex real-world cases. To evaluate its capabilities, we curated a…
Reasoning-based text-to-image (T2I) generation requires models to interpret complex prompts accurately. Existing reasoning frameworks can be broadly categorized into two types: (1) Text-Only Reasoning, which is computationally efficient but…
Language models excel at diagnostic assessments on curated medical case-studies and vignettes, performing on par with, or better than, clinical professionals. However, existing studies focus on complex scenarios with rich context making it…
Large Language Models (LLMs) generate fluent, plausible text that can mislead users into mistaking simulated coherence for genuine understanding. This paper introduces the Epistemic Suite, a post-foundational diagnostic methodology for…
Large language models (LLMs) are increasingly used for conversational clinical decision support, yet they conflate next token prediction with probabilistic decision making. We argue that this conflation reflects an architectural limitation:…
Rare diseases affect hundreds of millions worldwide, yet diagnosis often spans years. Convectional pipelines decouple noisy evidence extraction from downstream inferential diagnosis, and general/medical large language models (LLMs) face…
Bridging continuous perceptual signals and discrete symbolic reasoning is a fundamental challenge in AI systems that must operate under uncertainty. We present a neuro-symbolic framework that explicitly models and propagates uncertainty…