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Entity Linking (EL) is an essential and challenging task in natural language processing that seeks to link some text representing an entity within a document or sentence with its corresponding entry in a dictionary or knowledge base. Most…

Computation and Language · Computer Science 2024-02-26 Yifan Ding , Qingkai Zeng , Tim Weninger

Various template-based and template-free approaches have been proposed for single-step retrosynthesis prediction in recent years. While these approaches demonstrate strong performance from a data-driven metrics standpoint, many model…

Machine Learning · Computer Science 2023-08-15 Kevin Zhang , Vipul Mann , Venkat Venkatasubramanian

Large language models (LLMs) remain unreliable for high-stakes claim verification due to hallucinations and shallow reasoning. While retrieval-augmented generation (RAG) and multi-agent debate (MAD) address this, they are limited by…

Computation and Language · Computer Science 2026-05-13 Masnun Nuha Chowdhury , Nusrat Jahan Beg , Umme Hunny Khan , Syed Rifat Raiyan , Md Kamrul Hasan , Hasan Mahmud

Recent works have emerged in multi-annotator learning that shift focus from Consensus-oriented Learning (CoL), which aggregates multiple annotations into a single ground-truth prediction, to Individual Tendency Learning (ITL), which models…

Machine Learning · Computer Science 2026-02-02 Liyun Zhang , Fengkai Liu , Xuanmeng Sha , Bowen Wang , Hong Liu , Zheng Lian

Active learning (AL) aims to optimize model training and reduce annotation costs by selecting the most informative samples for labeling. Typically, AL methods rely on the empirical distribution of labeled data to define the decision…

Computation and Language · Computer Science 2025-07-23 Hui Xiang , Jinqiao Shi , Ting Zhang , Xiaojie Zhao , Yong Liu , Yong Ma

We present scPilot, the first systematic framework to practice omics-native reasoning: a large language model (LLM) converses in natural language while directly inspecting single-cell RNA-seq data and on-demand bioinformatics tools. scPilot…

Artificial Intelligence · Computer Science 2026-02-13 Yiming Gao , Zhen Wang , Jefferson Chen , Mark Antkowiak , Mengzhou Hu , JungHo Kong , Dexter Pratt , Jieyuan Liu , Enze Ma , Zhiting Hu , Eric P. Xing

Performing inference on large volumes of samples with large language models (LLMs) can be computationally and financially costly in industry and real-world use. We propose batch prompting, a simple yet effective prompting approach that…

Computation and Language · Computer Science 2023-10-25 Zhoujun Cheng , Jungo Kasai , Tao Yu

While large language models (LLMs) such as ChatGPT and PaLM have demonstrated remarkable performance in various language understanding and generation tasks, their capabilities in complex reasoning and intricate knowledge utilization still…

Computation and Language · Computer Science 2023-10-11 Haodi Zhang , Min Cai , Xinhe Zhang , Chen Jason Zhang , Rui Mao , Kaishun Wu

Single-cell RNA-seq data allow the quantification of cell type differences across a growing set of biological contexts. However, pinpointing a small subset of genomic features explaining this variability can be ill-defined and…

Machine Learning · Statistics 2022-07-29 Nabeel Sarwar , Wilson Gregory , George A Kevrekidis , Soledad Villar , Bianca Dumitrascu

Recent advances in Large Language Models (LLMs) have significantly improved table understanding tasks such as Table Question Answering (TableQA), yet challenges remain in ensuring reliability, scalability, and efficiency, especially in…

Computation and Language · Computer Science 2026-04-22 Sieun Hyeon , Jusang Oh , Sunghwan Steve Cho , Jaeyoung Do

Large language models (LLMs) are widely used in retrieval-augmented generation (RAG) to incorporate external knowledge at inference time. However, when retrieved contexts are noisy, incomplete, or heterogeneous, a single generation process…

Computation and Language · Computer Science 2026-04-22 Xingchen Xiao , Heyan Huang , Runheng Liu , Jincheng Xie

Can post-trained large language models (LLMs) further improve themselves using only unlabeled prompts, without external teachers or feedback from tools? We study this setting starting only from unlabeled seed questions with no ground-truth…

Computation and Language · Computer Science 2026-05-27 Tony Lee , Percy Liang

Computational methods to aid journalists in the task often require adapting a model to specific domains and generating explanations. However, most automated fact-checking methods rely on three-class datasets, which do not accurately reflect…

Computation and Language · Computer Science 2024-10-08 Jing Yang , Anderson Rocha

Efficient processing of tabular data is important in various industries, especially when working with datasets containing a large number of columns. Large language models (LLMs) have demonstrated their ability on several tasks through…

Machine Learning · Computer Science 2024-08-22 Ashlesha Akella , Abhijit Manatkar , Brij Chavda , Hima Patel

With the widespread adoption of pre-trained Large Language Models (LLM), there exists a high demand for task-specific test sets to benchmark their performance in domains such as healthcare and biomedicine. However, the cost of labeling test…

Computation and Language · Computer Science 2026-03-23 Aashish Anantha Ramakrishnan , Ardavan Saeedi , Hamid Reza Hassanzadeh , Fazlolah Mohaghegh , Dongwon Lee

We present SynCABEL (Synthetic Contextualized Augmentation for Biomedical Entity Linking), a framework that addresses a central bottleneck in supervised biomedical entity linking (BEL): the scarcity of expert-annotated training data.…

Computation and Language · Computer Science 2026-05-19 Adam Remaki , Christel Gérardin , Eulàlia Farré-Maduell , Martin Krallinger , Xavier Tannier

Combining multiple object detection datasets offers a path to improved generalisation but is hindered by inconsistencies in class semantics and bounding box annotations. Some methods to address this assume shared label taxonomies and…

Computer Vision and Pattern Recognition · Computer Science 2025-06-09 Mikhail Kennerley , Angelica Aviles-Rivero , Carola-Bibiane Schönlieb , Robby T. Tan

Large-scale single-cell and Perturb-seq investigations routinely involve clustering cells and subsequently annotating each cluster with Gene-Ontology (GO) terms to elucidate the underlying biological programs. However, both stages,…

Large language models (LLMs) face significant challenges when processing complex rule systems, as they typically treat interdependent rules as unstructured textual data rather than as logically organized frameworks. This limitation results…

Automated text annotation is a compelling use case for generative large language models (LLMs) in social media research. Recent work suggests that LLMs can achieve strong performance on annotation tasks; however, these studies evaluate LLMs…

Computation and Language · Computer Science 2024-09-24 Nicholas Pangakis , Samuel Wolken