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Related papers: Extracting Breast Cancer Phenotypes from Clinical …

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Both medical care and observational studies in oncology require a thorough understanding of a patient's disease progression and treatment history, often elaborately documented in clinical notes. Despite their vital role, no current oncology…

Computation and Language · Computer Science 2024-03-18 Madhumita Sushil , Vanessa E. Kennedy , Divneet Mandair , Brenda Y. Miao , Travis Zack , Atul J. Butte

The recent adoption of Electronic Health Records (EHRs) by health care providers has introduced an important source of data that provides detailed and highly specific insights into patient phenotypes over large cohorts. These datasets, in…

Accurate extraction of breast cancer patients' phenotypes is important for clinical decision support and clinical research. Current models do not take full advantage of cancer domain-specific corpus, whether pre-training Bidirectional…

Information Retrieval · Computer Science 2022-03-10 Sicheng Zhou , Liwei Wang , Nan Wang , Hongfang Liu , Rui Zhang

The digitalization of stored information in hospitals now allows for the exploitation of medical data in text format, as electronic health records (EHRs), initially gathered for other purposes than epidemiology. Manual search and analysis…

Large language models (LLMs) have immense potential to make information more accessible, particularly in medicine, where complex medical jargon can hinder patient comprehension of clinical notes. We developed a patient-facing tool using…

Unstructured notes within the electronic health record (EHR) contain rich clinical information vital for cancer treatment decision making and research, yet reliably extracting structured oncology data remains challenging due to extensive…

Objective: The generalizability of clinical large language models is usually ignored during the model development process. This study evaluated the generalizability of BERT-based clinical NLP models across different clinical settings…

Computation and Language · Computer Science 2023-03-16 Sicheng Zhou , Nan Wang , Liwei Wang , Ju Sun , Anne Blaes , Hongfang Liu , Rui Zhang

Background: Structured information extraction from unstructured histopathology reports facilitates data accessibility for clinical research. Manual extraction by experts is time-consuming and expensive, limiting scalability. Large language…

Cancer stage classification is important for making treatment and care management plans for oncology patients. Information on staging is often included in unstructured form in clinical, pathology, radiology and other free-text reports in…

Computation and Language · Computer Science 2024-09-04 Chia-Hsuan Chang , Mary M. Lucas , Grace Lu-Yao , Christopher C. Yang

Objective: There is a lot of information about cancer in Electronic Health Record (EHR) notes that can be useful for biomedical research provided natural language processing (NLP) methods are available to extract and structure this…

Quantitative Methods · Quantitative Biology 2019-04-04 Surabhi Datta , Elmer V Bernstam , Kirk Roberts

The unstructured nature of clinical notes within electronic health records often conceals vital patient-related information, making it challenging to access or interpret. To uncover this hidden information, specialized Natural Language…

Chemotherapy for cancer treatment is costly and accompanied by severe side effects, highlighting the critical need for early prediction of treatment outcomes to improve patient management and informed decision-making. Predictive models for…

Accurate extraction of Alzheimer's Disease and Related Dementias (ADRD) phenotypes from electronic health records (EHR) is critical for early-stage detection and disease staging. However, this information is usually embedded in unstructured…

Artificial Intelligence · Computer Science 2026-03-17 Mingchen Shao , Yuzhang Xie , Carl Yang , Jiaying Lu

Computational text phenotyping is the practice of identifying patients with certain disorders and traits from clinical notes. Rare diseases are challenging to be identified due to few cases available for machine learning and the need for…

Radiology reports capture crucial longitudinal information on tumor burden, treatment response, and disease progression, yet their unstructured narrative format complicates automated analysis. While large language models (LLMs) have…

Computation and Language · Computer Science 2026-03-12 Luc Builtjes , Alessa Hering

Clinical oncology generates vast, unstructured data that often contain inconsistencies, missing information, and ambiguities, making it difficult to extract reliable insights for data-driven decision-making. General-purpose large language…

Computation and Language · Computer Science 2025-03-12 Morteza Rohanian , Tarun Mehra , Nicola Miglino , Farhad Nooralahzadeh , Michael Krauthammer , Andreas Wicki

Manual chart review remains an extremely time-consuming and resource-intensive component of clinical research, requiring experts to extract often complex information from unstructured electronic health record (EHR) narratives. We present a…

Although supervised machine learning is popular for information extraction from clinical notes, creating large annotated datasets requires extensive domain expertise and is time-consuming. Meanwhile, large language models (LLMs) have…

Computation and Language · Computer Science 2024-01-26 Madhumita Sushil , Travis Zack , Divneet Mandair , Zhiwei Zheng , Ahmed Wali , Yan-Ning Yu , Yuwei Quan , Atul J. Butte

Objective: This review aims to analyze the application of natural language processing (NLP) techniques in cancer research using electronic health records (EHRs) and clinical notes. This review addresses gaps in the existing literature by…

Computation and Language · Computer Science 2025-02-05 Muhammad Bilal , Ameer Hamza , Nadia Malik

Recent rapid increase in the generation of clinical data and rapid development of computational science make us able to extract new insights from massive datasets in healthcare industry. Oncological clinical notes are creating rich…

Artificial Intelligence · Computer Science 2018-09-24 Marjan Najafabadipour , Juan Manuel Tuñas , Alejandro Rodríguez-González , Ernestina Menasalvas
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