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Identifying complex neural circuitry from electron microscopic (EM) images may help unlock the mysteries of the brain. However, identifying this circuitry requires time-consuming, manual tracing (proofreading) due to the size and intricacy…

Quantitative Methods · Quantitative Biology 2014-09-04 Stephen M. Plaza

Due to the inherent flexibility of prompting, foundation models have emerged as the predominant force in the fields of natural language processing and computer vision. The recent introduction of the Segment Anything Model (SAM) signifies a…

Image and Video Processing · Electrical Eng. & Systems 2024-01-09 Yichi Zhang , Zhenrong Shen , Rushi Jiao

Quantitative microstructural characterization is fundamental to materials science, where electron micrograph (EM) provides indispensable high-resolution insights. However, progress in deep learning-based EM characterization has been…

Computer Vision and Pattern Recognition · Computer Science 2025-08-25 Nan wang , Zhiyi Xia , Yiming Li , Shi Tang , Zuxin Fan , Xi Fang , Haoyi Tao , Xiaochen Cai , Guolin Ke , Linfeng Zhang , Yanhui Hong

In the domain of scientific imaging, interpreting visual data often demands an intricate combination of human expertise and deep comprehension of the subject materials. This study presents a novel methodology to linguistically emulate and…

Machine Learning · Computer Science 2023-09-27 Abdulelah S. Alshehri , Franklin L. Lee , Shihu Wang

Segment Anything Model (SAM) has revolutionized the way of segmentation. However, SAM's performance may decline when applied to tasks involving domains that differ from natural images. Nonetheless, by employing fine-tuning techniques, SAM…

Computer Vision and Pattern Recognition · Computer Science 2023-06-27 Lin Wang , Xiufen Ye , Liqiang Zhu , Weijie Wu , Jianguo Zhang , Huiming Xing , Chao Hu

Recent transformer-based architectures have shown impressive results in the field of image segmentation. Thanks to their flexibility, they obtain outstanding performance in multiple segmentation tasks, such as semantic and panoptic, under a…

Computer Vision and Pattern Recognition · Computer Science 2024-05-07 Niccolò Cavagnero , Gabriele Rosi , Claudia Cuttano , Francesca Pistilli , Marco Ciccone , Giuseppe Averta , Fabio Cermelli

The integration of scanning tunneling microscopy (STM) and electron spin resonance (ESR) spectroscopy has emerged as a powerful and innovative tool for discerning spin excitations and spin-spin interactions within atoms and molecules…

Mesoscale and Nanoscale Physics · Physics 2024-11-04 Lyuzhou Ye , Xiao Zheng , Xin Xu

Transmission electron microscopy (TEM) is a powerful imaging tool that has found broad application in materials science, nanoscience and biology(1-3). With the introduction of aberration-corrected electron lenses, both the spatial…

While electron microscopy offers crucial atomic-resolution insights into structure-property relationships, radiation damage severely limits its use on beam-sensitive materials like proteins and 2D materials. To overcome this challenge, we…

Computer Vision and Pattern Recognition · Computer Science 2025-07-18 Zifei Wang , Zian Mao , Xiaoya He , Xi Huang , Haoran Zhang , Chun Cheng , Shufen Chu , Tingzheng Hou , Xiaoqin Zeng , Yujun Xie

Comprehensive, synapse-resolution imaging of the brain will be crucial for understanding neuronal computations and function. In connectomics, this has been the sole purview of volume electron microscopy (EM), which entails an excruciatingly…

Image and Video Processing · Electrical Eng. & Systems 2023-03-03 Yicong Li , Yaron Meirovitch , Aaron T. Kuan , Jasper S. Phelps , Alexandra Pacureanu , Wei-Chung Allen Lee , Nir Shavit , Lu Mi

Microscopy has been key to tremendous advances in science, technology, and medicine, revealing structure and dynamics across time and length scales. However, combining high spatial and temporal resolution in a non-invasive, label-free…

Environmental microorganisms (EMs) are ubiquitous around us and have an important impact on the survival and development of human society. However, the high standards and strict requirements for the preparation of environmental…

Computer Vision and Pattern Recognition · Computer Science 2022-04-26 Peng Zhao , Chen Li , Md Mamunur Rahaman , Hao Xu , Pingli Ma , Hechen Yang , Hongzan Sun , Tao Jiang , Ning Xu , Marcin Grzegorzek

Instance segmentation in electron microscopy (EM) volumes is tough due to complex shapes and sparse annotations. Self-supervised learning helps but still struggles with intricate visual patterns in EM. To address this, we propose a…

Computer Vision and Pattern Recognition · Computer Science 2023-09-06 Yinda Chen , Wei Huang , Xiaoyu Liu , Shiyu Deng , Qi Chen , Zhiwei Xiong

(Scanning) transmission electron microscopy ((S)TEM) has significantly advanced materials science but faces challenges in correlating precise atomic structure information with the functional properties of devices due to its time-intensive…

High-fidelity numerical methods that model the physical layout of a device are essential for the design of many technologies. For methods that characterize electromagnetic effects, these numerical methods are referred to as computational…

Coherent spin resonance techniques, such as nuclear and electron spin resonance spectroscopy, have revolutionized non-invasive imaging by providing spectrally resolved information about spin dynamics. Motivated by the recent emergence of…

Quantum Physics · Physics 2026-02-25 Santiago Beltrán-Romero , Stefan Löffler , Dennis Rätzel , Philipp Haslinger

Transmission electron microscopy (TEM) is carried out in vacuum to minimize the interaction of the imaging electrons with gas molecules while passing through the microscope column. Nevertheless, in typical devices, the pressure remains at…

Mesoscale and Nanoscale Physics · Physics 2019-01-25 Gregor T. Leuthner , Stefan Hummel , Clemens Mangler , Timothy J. Pennycook , Toma Susi , Jannik C. Meyer , Jani Kotakoski

This paper presents a novel approach towards creating a foundational model for aligning neural data and visual stimuli across multimodal representationsof brain activity by leveraging contrastive learning. We used electroencephalography…

Computer Vision and Pattern Recognition · Computer Science 2024-11-18 Matteo Ferrante , Tommaso Boccato , Grigorii Rashkov , Nicola Toschi

Central to the application of many multi-view geometry algorithms is the extraction of matching points between multiple viewpoints, enabling classical tasks such as camera pose estimation and 3D reconstruction. Many approaches that…

Computer Vision and Pattern Recognition · Computer Science 2021-10-15 Alexander Mai , Allen Yang , Dominique E. Meyer

Foundation models, often pre-trained with large-scale data, have achieved paramount success in jump-starting various vision and language applications. Recent advances further enable adapting foundation models in downstream tasks efficiently…

Computer Vision and Pattern Recognition · Computer Science 2023-06-19 Dequan Wang , Xiaosong Wang , Lilong Wang , Mengzhang Li , Qian Da , Xiaoqiang Liu , Xiangyu Gao , Jun Shen , Junjun He , Tian Shen , Qi Duan , Jie Zhao , Kang Li , Yu Qiao , Shaoting Zhang